2,515 research outputs found
CORRECTION: The substrate-binding protein imposes directionality on an electrochemical sodium gradient-driven TRAP transporter (vol 106, pg 1778, 2009)
No full textBIOCHEMISTRY Correction for “The substrate-binding protein imposes directionality on an electrochemical sodium gradient-driven TRAP transporter,” by Christopher Mulligan, Eric R. Geertsma, Emmanuele Severi, David J. Kelly, Bert Poolman, and Gavin H. Thomas, which appeared in issue 6, February 10, 2009, of Proc Natl Acad Sci USA (106:1778–1783; first published January 28, 2009; 10.1073/pnas.0809979106).The authors note that due to a printer's error, on page 1782, the equations in Fig. 5 were missing the F constant. The corrected figure and its legend appear below.Fig. 5.Download figure Open in new tab Download powerpointFig. 5.Model of Na+-dependent transport of sialic acid by SiaPQM. The Upper image (Import Cycle) shows the uptake of sialic acid (denoted as asterisk), driven by a (electro)chemical Na+ gradient (ΔμNa + FΔΨ; F, Faraday constant). After binding of sialic acid (asterisk) to SiaP, the liganded complex docks onto SiaQM. A minimum of two sodium ions (black dots) bind to the complex and drive the translocation of sialic acid across the membrane; the sodium ions are cotransported with sialic acid, after which the system relaxes back to the initial conformation. The Lower image (Export Cycle) shows the efflux of sialic acid under conditions that an excess of unliganded SiaP is available. The critical point is that efflux of sialic acid only occurs when unliganded SiaP docks onto SiaQM with bound substrate. Assuming tight coupling in the transport reaction, two or more Na+ ions will be exported together with sialic acid
Ahead of others in the authorship order: names with middle initials appear earlier in author lists of academic articles in psychology
Full text linkMiddle name initials are often used by people in contexts where intellectual performance matters. Given this association, middle initials in people’s names indicate intellectual capacity and performance (Van Tilburg and Igou, 2014). In the current research, we examined whether middle initials are associated with a typical academic indicator of intellectual performance: authorship order of journal articles. In psychology, authorship early in the author list of an article should correspond with greater contribution to this intellectual endeavor compared to authorship appearing later in the author list. Given that middle initials indicate intellectual capacity and performance, we investigated whether there would be a positive relationship between middle initials in author names and early (vs. late) appearance of names in author lists of academic journal articles in psychology. In two studies, we examined the relationship between amount of authors’ middle initials and authorship order. Study 1 used a sample of 678 articles from social psychology journals published in the years 2006 and 2007. Study 2 used a sample of 696 articles from journals of multiple sub-disciplines in psychology published in the years from 1970 to 2013. Middle initials in author names were overrepresented early (vs. late) in author lists. We discuss implications of our findings for academic decisions on authorship orders, potential avenues of further investigation, and applications
An occupational survey to determine the entry level CAD skills and competencies required by employers of civil engineering technicians in the Northeast Wisconsin Technical College district
Full text linkIncludes bibliographical references.The purpose of this study was to identify the CAD related technical skills and
competencies that are required for employability at an entry-level position as a civil engineering technician. The majority of employers represented in this study are civil engineering firms, governmental agencies, and surveying firms. Overall, civil engineering firms along with governmental agencies employ the greatest number of drafters. Civil drawings, survey maps, and topographical drawings are the most commonly prepared drawings by the respondents. Other reported drawing types include architectural, electrical/electronic, landscaping, structural, and technical illustrations. Almost all of the respondents use a CAD system for drafting functions. AutoCAD is
the primary CAD platform used. MicroStation is also used, but to a much lesser extent. Of the employers that use CAD software, most use at least one collaborative software package with their primary CAD platform. Eagle Point is the most common collaborative software utilized. AutoCAD Land Development Desktop (ALDD) was noted to be the next commonly used collaborative software. Out of the 24 basic CAD skills that were listed on the survey, 14 were considered to be valid curriculum items and will be either retained or added to the program curriculum. Six of the 24 items will be reviewed for being valid curriculum items, and four of the items will not be included in the curriculum. Overall, most basic CAD skills were performed frequently or considered important. Out of the 29 advanced CAD skills that were listed on the survey, none were considered to be valid curriculum items. Sixteen of the 29 items will be reviewed for being valid curriculum items, and 13 of the items will not be included in the curriculum. Overall, most advanced CAD skills were not performed frequently nor considered important. Out of the 15 basic architectural drawing skills that were listed on the survey, none were considered to be valid curriculum items. Eight of the 15 items will be reviewed for being valid curriculum items, and seven of the items will not be included in the curriculum. Overall, most basic architectural drawing skills were not performed frequently nor considered important. None of the six basic structural drawing skills that were listed on the survey were considered to be valid curriculum items. One of the six items will be reviewed for being a valid curriculum item, and five of the items will not be included in the curriculum. Overall, most basic structural drawing skills were not performed frequently nor considered important
Vrioco(r)nium and Deva
No full textThe author restores the ancient name of Wroxeter, given as Viroconium in most sources, with the form Vrioconium [Cornovium]. The first element wrio-is an Indo-european name for “ stronghold”, attested in Thracian (Bria), Messapic (Uria), Tokharian (A ri, B, riye) ; any connection with Mycenian ri-jo-seems problematic.L’auteur restitue le nom antique de Wroxeter, le plus souvent Viroconium dans les sources, sous la forme Vrioconium [Cornovium]. Il dégage dans * wrio-un nom indo-européen de la forteresse, attesté en thrace (Bria), messapien (Uria), tokharien (A ri, B, riye), mais un rapport avec mycénien ri-jo-paraît problématique.Hamp Eric P. Vrioco(r)nium and Deva. In: Etudes Celtiques, vol. 36, 2008. pp. 69-74
ODF Landscape Resiliency Program : implementation and outcomes
Full text linkNaomi Serio, Michael R. Coughlan, Heidi Huber-Stearns, Anna Santo, Andy McEvoy, and Eric M. White.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references.Funding provided by the Oregon Department of Forestry (Agreement number M0177, Task order #5).Mode of access: Internet from the Oregon Government Publications Collection.Text in English
First in the Nation in Education : Final Report,1984.
No full textThis report is one step in an ongoing process of change and is a plea for commitment for high standards in education in Iowa. Contains the final reports of the six subcommittees as adopted by the Excellence in Education Task Force, and the five recommendations made by the Task Force
Review of Eric S. Nelson, ed. Interpreting Dilthey: Critical Essays (Cambridge: Cambridge University Press, 2019)
No full textThis wide-ranging, authoritative collection, edited by Eric S. Nelson, has the format of a Companion. It isn't labeled such since Wilhelm Dilthey has not yet attained the status of a canonized philosopher, perhaps due to the dearth of English translations of his writings, and even more to their intricacy. There is now, however, the landmark six-volume translation of Dilthey's major work, edited by Rudolf Makkreel and Frithjof Rodi (Princeton University Press, 1989-2019). Given the translation, this collection may well turn attention to Dilthey's work. This may happen soon given the emerging perception that philosophy is about both research and innovation, for Dilthey was indeed the author of quite well constructed and well pursued innovative philosophical strategies. Although it dates back to the turn of the twentieth century, Dilthey's work remains enormously relevant to current debates about science policy, art and literature, the biographical and autobiographical self, knowledge, language, science, culture, history, society, psychology, and the embodied self
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Supplementary information for section 5 of the book-chapter “Did seismic activity lead to the rise of religions?”
No full textSupplementary information for section 5 of Chapter 2, “Did seismic activity lead to the rise of religions?” by Jeanet Sinding Bentzen and Eric R. Force. Chapter published in The Economics of Religion (ed. Robert M. Sauer). World Scientific Publishing, June 2023. Book DOI: https://doi.org/10.1142/13328. Chapter DOI: https://doi.org/10.1142/9789811273148_0002.Unpublished supplementary information originally made available under bepress' Selected Works service. Added to UA Campus Repository after author received notification of bepress discontinuing the Selected Works service.This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]
Influence of CO2 on fishes in flowing water environments: implications for a non-physical barrier to movement
Full text linkSilver carp (Hypophthalmichthys molitrix) and bighead carp (H. nobilis) are invasive species that have become established in the upper reaches of the Illinois River, and are nearing the connection into Lake Michigan. To prevent the spread of these carp, as well as other fish, carbon dioxide (CO2) is being investigated as a potential nonphysical barrier. However, to date, most research on the effects of CO2 on fish behavior has occurred in static water conditions. Additionally, little is known about how elevated CO2 may affect swimming performance. Here, we investigate the effects that varying levels of dissolved CO2 will have on fish behavior and swimming performance in flowing water. Chapter 1 aims to identify threshold levels of CO2 required to elicit significant behavioral responses from the native surrogate species used (bluegill, Lepomis macrochirus, and largemouth bass, Micropterus salmoides). When exposed to a range of CO2 partial pressure (pCO2; < 400 μatm [ambient], 25,000 μatm, 50,000 μatm and 100,000μatm), bluegill showed a significant increase in activity at 25,000 μatm, whereas largemouth bass activity significantly increased at 100,000 μatm. Fish were also exposed to 50,000 μatm pCO2 in five successive bursts to investigate the effects of repeated exposure to CO¬2 on fish behavior. Both species displayed a significant increase in activity during the first exposure, but then successive exposures did not change activity levels relative to baseline (at ambient pCO2). Chapter 2 aims to quantify the effects of elevated CO2 on sustained (aerobic) and burst (anaerobic) swimming performance in largemouth bass. We found that sustained swimming performance significantly decreased at 100,000 μatm pCO2 and that burst swimming was unaffected by CO2. Additionally, ~15% of fish lost equilibrium during both sustained and burst swimming tests at 50,000 μatm, and nearly 70% of fish lost equilibrium during both sustained and burst swimming tests at 100,000 μatm, showing that the rate of loss of equilibrium significantly increased as pCO2 increased. These novel findings fill a knowledge gap regarding fish behavior and performance during exposure to elevated CO2 in flowing water, and also inform the development and deployment strategies of the proposed CO2 fish barriers.Submission published under a 24 month embargo labeled 'U of I Access', the embargo will last until 2019-08-01The student, Eric Schneider, accepted the attached license on 2017-06-22 at 10:28.The student, Eric Schneider, submitted this Thesis for approval on 2017-06-22 at 10:33.This Thesis was approved for publication on 2017-07-03 at 15:16.DSpace SAF Submission Ingestion Package generated from Vireo submission #11247 on 2017-09-29 at 10:45:59Made available in DSpace on 2017-09-29T17:45:25Z (GMT). No. of bitstreams: 2
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High-throughput cloning and expression in recalcitrant bacteria
Full text linkWe developed a generic method for high-throughput cloning in bacteria that are less amenable to conventional DNA manipulations. The method involves ligation-independent cloning in an intermediary Escherichia coli vector, which is rapidly converted via vector-backbone exchange (VBEx) into an organism-specific plasmid ready for high-efficiency transformation. We demonstrated VBEx proof of principle for Lactococcus lactis, but the method can be adapted to all organisms for which plasmids are available
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