101,123 research outputs found

    Five-year follow-up of a food-based vitamin A intervention in Tanzania

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    <p>Kidala D, Greiner T, Gebre-Medhin M. Five-year follow-up of a food-based vitamin A intervention in Tanzania. Public Health Nutrition 3:425-431, 2000.</p

    Letter, [Author unclear] to Paulina T. Merritt

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    Handwritten letter to Paulina Merritt from an unknown author, October 1, 1876.

    Supplementing lactating women with puréed papaya and grated carrots improved vitamin A status in a placebo-controlled trial

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    <p>Ncube TN, Greiner T, Malaba LC, and Gebre-Medhin M. Supplementing lactating women with puréed papaya and grated carrots improved vitamin A status in a placebo-controlled trial. Journal of Nutrition 131:1497-1502, 2001.</p

    Relationships between vitamin A, iron status and helminthiasis in Bangladeshi school children

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    <p>Persson V, Ahmed F, Gebre-Medhin M and Greiner T. Relationships between vitamin A, iron status and helminthiasis in Bangladeshi school children. Public Health Nutrition 3(1):83-89, 2000.</p

    Blindness is in the eye of the beholder. Reply to NL Sloan and NW Solomons

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    <p>Greiner T, Gebre-Medhin M, and Persson V. Blindness is in the eye of the beholder. Reply to NL Sloan and NW Solomons. Food and Nutrition Bulletin 20:367-9, 1999.</p> <p>In this letter we defend our stance that the Helen Keller Food Frequency Method of assessing community vitamin A status underestimates vitamin A status when breastfeeding is prolonged--as it is in South Asia where a substantial proportion of the world's severe vitamin A deficiency is located. </p

    Information and socioeconomic factors associated with early breastfeeding practices in rural and urban Morogoro

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    <p>Shirima R, Gebre-Medhin M and Greiner T. Information and socioeconomic factors associated with early breastfeeding practices in rural and urban Morogoro, Tanzania. Acta Paediatrica 90:936-942, 2001.</p> <p>Exclusive breastfeeding is a traditional behavior (the norm within living memory) virtually nowhere. In this sample of women from both an urban and a rural area of Tanzania, this was reflected in the fact that the only factor correlated with the duration of exclusive breastfeeding was knowledge about it. </p

    Exclusive breastfeeding is rarely practiced in rural and urban Morogoro, Tanzania

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    <p>Shirima R, Greiner T, Kylberg E, and Gebre-Medhin M. Exclusive breastfeeding is rarely practiced in rural and urban Morogoro, Tanzania. Public Health Nutrition 4(2):147-154, 2001.</p> <p>Early infant feeding practices were found to be better in the urban than in the near by rural sample but few mothers exclusively breast fed in either. </p

    The Helen Keller International Food Frequency Method may underestimate vitamin A intake where milk is a normal part of the young child diet

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    <p>Persson V, Greiner T, Bhagwat IP, and Gebre-Medhin, M. The Helen Keller International Food Frequency Method may underestimate vitamin A intake where milk is a normal part of the young child diet. Ecology of Food and Nutrition.38:57-69, 1999.</p

    Handwritten biographical information on Paulina T. McClung Merritt

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    A handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.

    Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.

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    IFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
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