29 research outputs found
ROUTINE INVASIVE VERSUS CONSERVATIVE STRATEGY FOR ELDERLY PATIENTS AGED>75 YEARS WITH NON-ST ELEVATION ACUTE CORONARY SYNDROME (NSTE-ACS): A META-ANALYSIS OF RANDOMIZED CONTROLLED TRIALS
No full textCOMPARISON OF IN-HOSPITAL OUTCOMES OF TRANSCATHETER AORTIC VALVE REPLACEMENT IN MEN AND WOMEN
No full textHyperkalemia among hospitalized patients and association between duration of hyperkalemia and outcomes.
No full textINTRODUCTION: The aim of the study was to investigate predictors of mortality in patients hospitalized with hyperkalemia.
MATERIAL AND METHODS: Data among hospitalized patients with hyperkalemia (serum potassium ≥ 5.1 mEq/l) were collected. Patients with end-stage renal disease on dialysis were excluded.
RESULTS: Of 15,608 hospitalizations, 451 (2.9%) episodes of hyperkalemia occurred in 408 patients. In patients with hyperkalemia, chronic kidney disease, hypertension, diabetes, coronary artery disease and heart failure were common comorbidities. Acute kidney injury (AKI) and metabolic acidosis were common metabolic abnormalities, and 359 patients (88%) were on at least one drug associated with hyperkalemia. Mean duration to resolution of hyperkalemia was 12 ±9.9 h. Nonsteroidal anti-inflammatory drugs (HR = 1.59), highest potassium level (HR = 0.61), tissue necrosis (HR = 0.61), metabolic acidosis (HR = 0.77), and AKI (HR = 0.77) were significant independent determinants of duration prior to hyperkalemia resolution. Tissue necrosis (OR = 4.55), potassium supplementation (OR = 5.46), metabolic acidosis (OR = 4.84), use of calcium gluconate for treatment of hyperkalemia (OR = 4.62), AKI (OR = 3.89), and prolonged duration of hyperkalemia (OR = 1.06) were significant independent predictors of in-hospital mortality.
CONCLUSIONS: Tissue necrosis, potassium supplementation, metabolic acidosis, calcium gluconate for treatment of hyperkalemia, AKI and prolonged duration of hyperkalemia are independent predictors of in-hospital mortality
A View of the Restaurant Script Through the Lens of Hierarchical Planning
No full textThe flexible nature of human cognition and of the structures it uses is well known, as is the difficulty of building cognitive systems that exhibit transfer and use the same structures for radically different tasks. In this paper, we perform a close examination of Schank-Abelsonian scripts, picking apart the goal- and plan- oriented nature of low-level acts and high-level reasoning inherent in them. We then view scripts through the lens of hierarchical planning systems and construct the well-known restaurant script as a hierarchical goal network planning domain. These are evidence in support of a claim that some, if not all, scripts are deeply hierarchical and are plan- and goal-oriented. The continuum that results from this representational unification may provide flexible knowledge structures which may be reused across a broad variety of tasks in language understanding, planning, and tasks requiring both, such as explanation and plan-based understanding of natural language
A rare concurrence: nonischemic cardiomyopathy and multiple myeloma without amyloidosis.
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Staged versus index procedure complete revascularization in ST-elevation myocardial infarction: A meta-analysis.
No full textBACKGROUND: Complete revascularization of patients with ST-elevation myocardial infarction and multivessel coronary artery disease reduces adverse events compared to infarct-related artery only revascularization. Whether complete revascularization should be done as multivessel intervention during index procedure or as a staged procedure remains controversial.
METHOD: We performed a meta-analysis of randomized controlled trials comparing outcomes of multivessel intervention in patients with ST-elevation myocardial infarction and multivessel coronary artery disease as staged procedure versus at the time of index procedure. Composite of death or myocardial infarction was the primary outcome. Mantel-Haenszel risk ratios were calculated using random effect model.
RESULTS: Six randomized studies with a total of 1126 patients met our selection criteria. At a mean follow-up of 13 months, composite of myocardial infarction or death (7.2% vs 11.7%, RR: 1.66, 95%CI: 1.09-2.52, P = 0.02), all cause mortality (RR: 2.55, 95%CI: 1.42-4.58, P \u3c 0.01), cardiovascular mortality (RR: 2.8, 95%CI: 1.33-5.86, P = 0.01), and short-term (
CONCLUSION: In patients with ST-elevation myocardial infarction and multivessel coronary artery disease, a strategy of complete revascularization as a staged procedure compared to index procedure revascularization results in reduced mortality without an increase in repeat myocardial infarction or need for repeat revascularization
Staged versus index procedure complete revascularization in ST-elevation myocardial infarction: A meta-analysis
No full textSafety and Efficacy of Dual Versus Triple Antithrombotic Therapy in Patients Undergoing Percutaneous Coronary Intervention
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