1,721,020 research outputs found
Intractable chronic pruritus as the only manifestation of IgE hypersensitivity to Anisakis
No full textAdverse reactions to tattoos [Reazioni avverse ai tatuaggi]
No full textTattooing has been practiced for centuries in many cultures and has become increasingly popular in Western countries since the 1970s, with a parallel increase in adverse reactions. Tattoo-associated skin reactions include transient acute inflammatory reactions due to the piercing of the skin with needles and true medical complications such as allergic contact dermatitis, photodermatitis, granulomatous, lichenoid and pseudolymphomatous reactions, contact urticaria, reactions triggered by magnetic resonance imaging and laser, localization of skin cancer or other skin diseases in the tattoo. For the diagnosis of allergic contact dermatitis, patch testing with traditionally involved allergens such as mercury, chromium and cobalt are often inadequate, because the composition of tattoo inks has changed considerably and keeps changing. Moreover, in Italy the composition of tattoo inks is not regulated by law and their labeling is not compulsory. Red tattoos were and are the most frequent cause of allergic contact dermatitis. However, nowadays most reactions are not due to the traditional presence of mercury sulphide but to new organic pigments. Some of these penetrate the skin poorly, even under occlusion. Patch testing could thus be insufficient for the diagnosis and prick testing with a delayed reading may be required. Despite these difficulties, new allergens are beginning to be identified. © Monte Meru Editrice
Aquagenic urticaria [Orticaria acquagenica]
No full textAquagenic urticaria (AU) is a form of inducible urticaria characterized by whealing at the site of skin contact with water, regardless of its temperature, within minutes of exposure. Approximately sixty cases, quite heterogeneous with regard to their severity and source of elicitation, have been reported in the literature. The clinical manifestations may be triggered by different types of water in different patients. There are forms that develop after exposure to salty water, forms that develop after contact with tap water, and even forms that are triggered by sweat, tears or a damp environment. A special form of OA has recently been identified, salt-dependent aquagenic urticaria (SDAU). This is characterized by being induced exclusively or predominantly by salty water, to occur in women of child bearing age and to involve the lower facial contours. The pathogenesis of AU is obscure. The disease is considered rare but it is probably underestimated, as mild cases do not come to the attention of dermatologists or may be misinterpreted as simple irritant reactions
Lichen planus presenting with erythema-multiforme-like bullous lesions in a patient with systemic scleroderma
No full textA patient with systemic scleroderma is described who developed a cutaneous eruption of papules and vesicobullae. Over time, the latter turned into papules. The histopathological and immunofluorescence features of the papular lesions were unequivocally those of lichen planus, while those of the bullous lesions reminded of erythema multiforme. Histologically, erythema multiforme shares common features with lichenoid reactions, such as necrotic keratinocytes. Our case suggests that erythema multiforme and lichen planus may coexist or succeed each other as different stereotype immune reactions against the same antigen(s) within the epidermis
Dermato-neuro Syndrome after COVID-19 Vaccination in a Patient with Scleromyxoedema Previously Controlled with Bortezomib and Intravenous Immunoglobulins
No full textPrevalence of sensitization to methylisothiazolinone in an italian skin allergy unit
No full textAn alarming increase in the prevalence of sensitization to the preservative methylisothiazolinone (MI), alone or in combination with methylchloroisothiazolinone (MCI), has recently been reported, mainly in Northern Europe. Prevalence data from Southern Europe are scanty. We evaluated the prevalence of contact allergy to MI and MCI/MI among 1392 patients consecutively patch tested in 2012 - 2013 at the Clinica Dermatologica of San Martino Hospital, Genoa, Italy. The patients were patch tested with 2000 ppm MI aq. in addition to the Italian baseline series. The MOAHLFA index was registered for all patients. Relevant exposures to MI and/or MI/MCI were determined and the patients' clinical outcome after isothiazolinones avoidance was evaluated. The prevalence of sensitization to MI showed a steep increase of prevalence from 2.3% in 2012 to 6.9% in 2013 while sensitization to MI/MCI rose from 6.76% in 2012 to 9.04% in 2013. Hand and face dermatitis were significantly prevalent in MI allergic patients. Cosmetics, followed by household products, were the most common sources of relevant exposure to both MI and MI/MCI. Clinical improvement after avoidance of isothiazolinones containing products was reported by 85.3% of followed up patients
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