4,722 research outputs found
Early Detection of Central Visual Function Decline in Cone-Rod Dystrophy by the Use of Macular Focal Cone Electroretinogram
No full textPURPOSE. To evaluate macular focal cone ERG (fERG) as a tool for reliable and early detection
of central retinal function decay in cone–rod dystrophy (CRD).
METHODS. A retrospective study of the time course of fERG amplitude and its relation to visual
acuity alterations was performed in 47 CRD patients followed yearly for 6.0 6 3.1 years.
Macular focal cone ERG was evoked by a flickering uniform red field overlaying the central
188 of visual field.
RESULTS. Macular focal cone ERG follow-up allowed a clear-cut identification of CRD patients
as stationary or progressive, in agreement with visual acuity follow-up. In all progressive
patients, fERG declined whenever visual acuity declined, and—in 50% of the cases—fERG loss
anticipated acuity loss of several years.
CONCLUSIONS. Macular focal cone ERG represents a sensitive assay to detect, categorize, and
follow the progression of central retinal dysfunction in CRD. Its use as a diagnostic tool in
CRD may help anticipate, for an individual patient, the likelihood and rate of further disease
progression before visual acuity loss has occurred
The spatial order of horizontal cells is not affected by massive alterations in the organization of other retinal cells.
No full textLa tragedia di uno schiavo in un discorso di Metello Scipione (Ascon. 35,7—11 = ORF 154, F2 Manuwald)
No full textL’articolo si propone di ricostruire un episodio attestato unicamente nel discorso pronunciato in senato verso il 18 febbraio 52 a. C. da Quinto Metello Scipione, che noi conosciamo attraverso una sintesi di Asconio (35,7–10). Secondo la ricostruzione presentata nell’articolo, Scipione avrebbe attribuito a Milone, del quale sottolineava la fredda ferocia, l’intento di uccidere il figlio bambino di Clodio; nel tentativo di trovarlo, Milone avrebbe fatto sottoporre ad un violentissimo interrogatorio lo schiavo che si prendeva cura del bambino, ma questi, pur di non tradire i suoi padroni, sarebbe morto sotto le torture. L’episodio veniva sfruttato da Scipione a scopo patetico, per suscitare indignazione contro Milone e ammirazione per lo schiavo fedele del quale, eccezionalmente, era fornito anche il nome. Non è possibile pronunciarsi sull’attendibilità di questa vicenda, testimoniata da un’unica fonte molto tendenziosa, ma è significativo che Asconio non la includa nella propria versione dei fatti.
This article aims to reconstruct an episode recorded only in the speech delivered by Quintus Metellus Scipio in the Senate on 18 February 52 BC; Scipio’s speech is known to us from a summary by Asconius (35,7–10). According to the reconstruction presented in the article, Scipio attributed to Milo – whose cold ferocity was emphasised – the intention of killing Clodius’ young son. Milo was said to have violently interrogated the slave responsible for looking after the child in an attempt to find the boy, but the slave died under torture rather than betray his masters. Scipio exploited the episode for emotional effect, aiming to arouse indignation against Milo and admiration for the loyal slave, whose name, exceptionally, was also recorded. The reliability of this story, which comes from a highly biased source, is impossible to verify, but notably, Asconius did not include it in his own account of the facts
‘Nisi probrum’ (Accius, ‘Hellenes’ 384 R.3 e Cic. ‘rep.’ 4. 4)
No full textComparing Accius, v. 384 R.3 (from Hellenes) with Cic. rep. 4, 4, we can find a reference to Spartan sexual habits, more specifically to paederasty
Una lacuna nell’esordio della ‘pro Milone’? Nota al testo di Cic. ‘Mil.’ 2
No full textThis paper argues for the resumption of a conjecture by Garatoni in Cic. Mil. 2 (nec illa praesidia instead of non illa praesidia), as well as for the omission of terroris; and for the revaluation of Birt’s hypothesis of a loss of some lines in our tradition
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