1,721,318 research outputs found
Letter to the Editor Re: Coronavirus disease 2019: The harms of exaggerated information and non‐evidence‐based measures
No full textMisinformation led to an erroneous perception of risk in some cases with the consequent lack of adoption of preventive interventions and in others to unmotivated and irrational behaviour (eg panic shopping, shortage of supplies for personal protection such as face masks). Certainly, there is a need to acquire and/or deepen our scientific knowledge on this pandemic, since we know little about many aspects (eg immune response, duration of immune protection and effectiveness of adopted interventions), but we cannot prevent to adopt those measures that, although important and limiting personal freedoms, can avoid further and worse issues, in order to contain the spreading of the virus, and to reactivate as soon as possible the national economic system before its disruption
Ongoing Threats for Older Europeans: Diphtheria, Pertussis and Tetanus
No full textDiphtheria, tetanus and pertussis represent an ongoing health threat across the world, and long-term immune protection does not exist for these diseases. Tetanus is the only non-communicable vaccine-preventable disease (VPD). It occurs mainly in older patients, during the warmer months when outdoor activity is higher, and its current epidemiology in Europe may be explained by lack of vaccination or waning immunity. Despite the low number of cases, tetanus is severe with high mortality, and thus, maintaining high vaccination coverage is important. Diphtheria is a potentially acute disease caused by exotoxin-producing Corynebacterium diphtheriae. It is affected by waning immunity, although the majority of reported cases are in unvaccinated adults or those with unknown vaccination status. It is therefore important to maintain high coverage rates as immunisation is the only effective method of preventing this toxin-mediated disease. Particular attention should also be given to revaccination of healthcare and social workers due to waning immunity. Finally, pertussis continues to represent a major cause of death in infants worldwide despite high vaccination coverage, whereas the clinical presentation of pertussis in adolescents and adults can be mild and often goes unrecognised. Indeed, reported pertussis incidence has increased markedly in recent years in almost all European countries, despite sustained high vaccine coverage, again highlighting the effect of waning vaccine immunity. Outbreaks in areas of high vaccination coverage highlight that vaccination strategies may need to be revisited and that consideration should be given to adolescent and adult boosters
Possible pitfalls of the 2017 ECIL guidelines
No full textCommentary on 2017 European Conference on Infections in Leukaemia (ECIL) guidelines for vaccination of haemopoietic stem-cell transplant (HSCT) recipients and ECIL guidelines for vaccination of patients with haematological malignancies
Trends in Hospital Admissions for Pertussis Infection: A Nationwide Retrospective Observational Study in Italy, 2002-2016
No full textBackground: Pertussis is a highly contagious infectious disease which continues to be an important public-health issue despite the high immunization coverage rates achieved. However, evidence of increased circulation of pertussis among adolescents and adults due to waning immunity and atypical clinical manifestations seem to be the main reasons for its resurgence. The aim of this study was the analysis of the epidemiological trend for pertussis-related hospitalizations in Italy, in relation with vaccination coverage and information from laboratory confirmed cases of pertussis.Methods: A retrospective observational study investigating hospitalizations for pertussis from 2002 to 2016 in Italy was conducted. Frequencies and rates of hospitalization were analyzed and hospitalization data were compared with a series of already published laboratory confirmed data. Results: This study highlighted a rising trend for pertussis hospitalizations in Italy since 2008. Infants aged <1 year showed the highest frequencies (63.39%) and average rates (74.60 × 100000 infants) of hospitalization despite an extremely high vaccination coverage (95.89%). An increasing trend of hospitalization frequency emerged for the age group with levels of IgG antibodies to pertussis toxin compatible with pertussis infection within the last year (20-29 years old age group). Conclusions: The rising trend for pertussis hospitalizations and the greater involvement of infants aged <1 year require an integrated approach, including the implementation of booster doses administration in adolescence and adulthood, the vaccination of pregnant women and the cocoon strategy
CENTRO NAZIONALE OMS PER L'INFLUENZA: SORVEGLIANZA VIROLOGICA DELL'INFLUENZA IN ITALIA (STAGIONE 2005-2006)
No full textComparative survival of fecal and human contaminants and use of Staphylococcus aureus as an effective indicator of human pollution
No full textGROUNDWATER QUALITY IN THE PROVINCE OF LECCE : CRITICAL REVISION OF THE HISTORICAL DATE.
No full textPrevalenza degli anticorpi verso il Toxoplasma Gondii. Studio su un campione di popolazione genovese
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