1,720,977 research outputs found
Optimizing aesthetic outcomes after goldilocks mastectomy: A new method of nipple reconstruction
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Il rimodellamento del solco sottomammario in seguito ad espansione cutanea post-mastectomia
No full textStudio comparativo strutturale sulla valvola di riempimento degli espansori mammari: il nostro punto di vista
No full textMicrosurgical latissimus dorsi flap in a case of breast aplasia caused by radiation therapy
No full textThe use of ionizing radiation in the breast region while a patient is at developmental age is still responsible for most monolateral hypoplasias and iatrogenic-based breast asymmetries. These alterations often involve several anatomical structures, thus causing severe hypoplasia of the breast and muscle tissues and stiffness of soft tissues, with atrophic and cicatricial skin. Reconstruction methods vary from case to case, but most of the time reconstruction with a homolateral latissimus dorsi with or without a breast implant seems most suitable. In some cases, however, this is not a viable alternative due to particular general and local conditions, making it necessary to consider other solutions. We present the case of a young prepubertal patient who came under our observation due to a radiotherapy outcome in the right breast and thoracic region; she had been previously subjected to breast reconstruction elsewhere, with the fitting of a subcutaneous prosthesis. Due to the patient's particular general and local conditions and the pathological involvement of the homolateral thoracic musculature, to improve the clinical picture, we deemed it appropriate to use the microsurgical reinnervated contralateral latissimus dorsi muscle, which so far has enabled us to obtain considerable and lasting results
Autologous micrografts and methotrexate in plantar erosive lichen planus: healing and pain control. A case report
Full text linkErosive lichen planus is an uncommon variant of lichen planus. We report a case of long-standing and refractory plantar ELPs causing disabling and opiate-resistant pain treated with 'classic' meshed skin graft combined with RigeneraVR micrografts. After approximately 9 months follow-up, no clinical recurrence or pain were observed. Erosive lichen planus (ELP) is an uncommon variant of lichen planus, involving oral cavity and genitalia and, less often plantar areas, where it usually presents with chronic erosions of the soles, along with intense, disabling pain and progressive loss of toenails. An abnormal immune cellular response (CD8+ lymphocytes and macrophages) and the consequent altered production of multiple mediators (interleukin-12, interferon-gamma, tumor necrosis factor-alpha, RANTES and MMP-9), seem to play a crucial role in the pathogenesis, although the etiology remains uncertain. From a histological point of view, ELP shows keratinocyte apoptosis, intense inflammatory response and basal epithelial keratinocytes TNF-alpha overexpression. Several therapies have been proposed, with variable and controversial results. While topical corticosteroids and topical calcineurin inhibitors are the treatments of choice for localized forms, short pulses of systemic glucocorticoids, phototherapy, and systemic immunosuppressants are recommended for generalized cases. Surgery has been reported as a possible therapeutic option in refractory and stable cases with localized lesions, either alone or with cyclosporine. Herein, we report a case of longstanding and refractory plantar ELPS causing disabling and opiate-resistant pain treated with 'classic' meshed skin graft combined with RigeneraVR micrografts
An easy and cheap way of staining the arterial supply of the face: a preclinical study of visualization of facial vascular territories in human cadavers
No full textINTRODUCTION:
A cadaver study in preparation of a facial allograft transplantation in humans requires accurate dissection of the arterial, venous and nerve pedicles. A simple and cheap method for the use of arterial tree mapping in cadaver soft tissue is presented.
MATERIALS AND METHODS:
Eight fresh cadavers aged 55-89 years at the time of death were studied. Five were female and three were male. All injections were performed within four post-mortem days.
RESULTS:
Our method determined the perfusion territories of the human face without risk of spillage of the dye from capillary structures and showed the arteries very clearly. Vascular patterns of the face were interpreted after dyed gel mixture injection.
CONCLUSION:
This study confirms the current reconstructive procedures on the face, but also helps and allows the anatomical dissection to be carried out in an effective and safe manner. The dyed gel mixture represents a valid, cheap and alternative tool for delineating the vascular structures, without leakage and spillage during the anatomical dissection
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