88,782 research outputs found

    F. Giardina, La condizione giuridica del minore

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    F. Giardina, La condizione giuridica del minore. In: Revue internationale de droit comparé. Vol. 37 N°2, Avril-juin 1985. p. 474

    F. Giardina, La condizione giuridica del minore

    No full text
    F. Giardina, La condizione giuridica del minore. In: Revue internationale de droit comparé. Vol. 37 N°2, Avril-juin 1985. p. 474

    Discussion sur la communication d’Andrea Giardina

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    [La communication d’A. Giardina, “L’Italia nel sistema imperiale: tra economiae politica” n’a pas été insérée dans ce volume à la demande de l’auteur, qui a cependant revu sa réponse aux interventions de F. Coarelli, D. Foraboschi et E. Lo Cascio lors de la discussion] F. COARELLI: La relazione di Giardina pone problemi un po’più ampi, trattandosi di una relazione diciamo metodologica, in cui è inevitabile affrontare punti che sono emersi un po’da tutto il dibattito precedente. Mi pare import..

    Protein dynamics in minimyoglobin: is the central core of myoglobin the conformational domain?

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    The kinetics of CO binding to the horse myoglobin fragment Mb-(32-139), the so-called "mini-Mb," were investigated by laser flash photolysis in 0.1 M phosphate buffer and in buffer with 75\% (vol/vol) glycerol. The reaction displays complex time courses that can be approximated satisfactorily only with a sum of five exponentials. The features of the kinetic components and a comparison of the deoxy-minus-carbonyl difference spectra of mini-Mb and horse Mb obtained under equilibrium conditions, with the kinetic difference spectra resulting from the global analysis of the traces recorded between 400 and 450 nm, show that CO binding to mini-Mb is accompanied by large structural changes. In view of the fact that mini-Mb is an approximation of the Mb-(31-105) fragment encoded by the central exon of the Mb gene, this finding is particularly relevant. On the basis of our data and previous reports [De Sanctis, G., Falcioni, G., Giardina, B., Ascoli, F. & Brunori, M. (1988) J. Mol. Biol. 200, 725-733; De Sanctis, G., Falcioni, G., Grelloni, F., Desideri, A., Polizo, F., Giardina, B., Ascoli, F. & Brunori, M. (1992) J. Mol. Biol. 222, 637-643], we propose that the protein fragment encoded by the central exon of the Mb gene is the domain responsible for ligand-linked conformational transitions, while the two terminal fragments dampen the amplitude of the structural changes that accompany ligand binding, thus rendering the protein stable and kinetically more efficient in its physiological function

    Atmospheric dry deposition processes of particles on urban and suburban surfaces: Modelling and validation works

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    Dry deposition process is one of the important pathways for the removal of particles from atmosphere. It is the result of a combination of different environmental and physical factors as atmospheric conditions, particle properties, characteristics of the canopy. For this latter factor, urban canopy represents unevenly combinations of different types of surface elements that increases the complexity of deposition process phenomena. Therefore, particle dry deposition on urban surfaces is not easy to configure and, although empirical or semi-empirical models in literature have been developed to address this aspect, there is not standardized and commonly accepted criteria, especially for submicron particles. In this paper, comparisons of different dry deposition models and measurement data by experimental campaigns, covering for different surface roughness conditions, i.e. from four Italian cities and urban environments of other countries, are performed. Giardina et al. (2017b) model, by using a Brownian diffusion resistance as proposed in this paper, seems to capture the main dry deposition processes for the examined contexts

    Di chi sono i geni? Guida per i perplessi

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    Il problema del riconoscimento e della allocazione dei diritti sull’informazione genetica è affrontato per mezzo di una serie di distinzioni: tra materiale genetico, come unità minima di significato biologico, e le informazioni estratte dalla sua manipolazione; tra materiale genetico modificato e non modificato; tra genoma umano e non umano; tra informazione genetica primaria e secondaria. Il saggio illustra i regimi giuridici e le problematiche anesse alle diverse tipologie di informazione, soffermandosi in particolare sulla questione dell’uso dei dati come contenuto di un obbligo giuridico precontrattuale di condivisione dell’informazione strumentalmente coordinato a una prestazione di dare o facere, il cui inadempimento è causa legittima di rifiuto di stipulare il contratto di assicurazione, ovvero d’invalidità o recesso dal contratto stipulato
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