1,721,189 research outputs found
Gamma Knife surgery in ophthalmologic disorders: uveal melanoma. (Abstract). Scientific Program and Schedule of Events (Abstract Book).
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Cerebral gliomas : proceedings of the International Workshop on Brain Tumors, held in Santa Margherita Ligure, Italy, 20-22 June 1988
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Comments on "Role of radiosurgery in the management of cerebral arteriovenous malformations in the pediatric age group: Data from a 100-patient series".
No full textVM-26 monochemotherapy trial in the treatment of recurrent supratentorial gliomas: preliminary report
No full textTwenty-five adults with recurrent supratentorial malignant gliomas were treated with VM-26 in a monochemotherapy schedule, the antiblastic region covering a period of 24 weeks. Five cases were excluded from the final evaluation, 4 because of protocol violations and 1 due to intolerance to the drug. In the group of 20 patients who met the criteria for evaluation, 7 (35\%) showed a partial or complete response, with clinical or radiological tumor aggression, and the conditions of 7 (35\%) were unchanged at the end of the chemotherapy courses. The progression-free intervals turned out to be 10.4 months and 8.5 months, respectively. Six patients (30\%) complained of tumor progression despite the treatment. Most of the patients are still alive, and the actuarial survival rate is encouraging. Toxicity was mainly hematologic, but usually moderate and easily reversible
Intracranial arterio-venous malformations. Gamma Knife radiosurgery as a primary therapeutic option.
No full textCSF levels of cyclic nucleotides in primary intracranial neoplasms: a preliminary report
No full textRecent evidence indicates that cyclic nucleotides are of importance for general and neurosurgical oncology, especially with respect to the contact-inhibition mechanisms and tumour cell growth. This preliminary report deals with the CSF levels of c-AMP and c-GMP in primary neoplasms in children and to problems related to the blood-brain barrier. Some cases of medulloblastoma were studied as well as a few cases of brain stem glioma and cystic astrocytoma. The importance of some rather unusual findings seems undebatable, i.e., the marked increase in c-GMP values usually observed in medulloblastoma and the decrease of c-AMP, that is fairly common in all malignant neoplasms. The main changes in the c-AMP/c-GMP ratio are also discussed
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