1,721,594 research outputs found

    Accuracy of New CT Scanner in the Diagnosis of Coronary In-Stent Restenosis [Response]

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    Comment on: D. Andreini, G. Pontone, S. Mushtaq, A.L. Bartorelli, E. Bertella, D. Trabattoni, P. Montorsi, S. Galli, C. Foti, A. Annoni et al., Coronary in-stent restenosis: assessment with CT coronary angiography. Radiology 2012 Nov; 265(2):410-7. J. Ding, M. Li, G. Sun, Accuracy of new CT scanner in the diagnosis of coronary in-stent restenosis. Radiology. 2013 Apr; 267(1):315-6

    Reply

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    Comment on: D. Andreini, G. Pontone, S. Mushtaq, A.L. Bartorelli, E. Bertella, L. Antonioli, A. Formenti, S. Cortinovis, F. Veglia, A. Annoni, et al., A long-term prognostic value of coronary CT angiography in suspected coronary artery disease, JACC Cardiovasc Imaging. 2012 Jul; 5(7):690-701. P. Goncalves, M.M. Garcia-Garcia, Prognostic value of coronary CT angiography, JACC Cardiovasc Imaging. 2013 Jan; 6(1):127-8

    DIAGNOSTIC ACCURACY OF COMPUTED TOMOGRAPHY CORONARY ANGIOGRAPHY FOR EVALUATION OF CORONARY ARTERY DISEASE IN HIGH RISK PATIENTS: A COMPARISON BETWEEN HIGH (0.23 MM) VERSUS STANDARD (0.625 MM) SPATIAL RESOLUTION SCANNER

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    Purpose: To compare the image quality, evaluability, diagnostic accuracy and radiation exposure of high spatial resolution computed tomographic coronary angiography (HD-CCTA) versus standard spatial resolution 64-slice scanner (SD-CCTA) in high-risk patients for coronary artery disease (CAD) by using invasive coronary angiography (ICA) as the reference method. Material and Methods: Written informed consent was obtained from all patients and the study protocol was approved by the institutional ethical committee. One-hundred-eighty-four consecutive high risk patients for CAD and scheduled for ICA were randomly studied by SD-CCTA (n=91) or HD-CCTA (n=93) before ICA. To compare the two groups, Student’s test or Wilcoxon’s test were used to evaluate differences of continuous variables, the Chi-square test or Fisher’s exact test when appropriate were used regarding to categorical data and McNemar’s test was used to compare the diagnostic performance of CCTA versus ICA in each group. Results: HD-CCTA showed a higher image quality score (3.7 vs 3.4, p:0.0001) and evaluability (97% vs 92%, p<0.002). In a segment-based analysis, HD-CCTA showed a higher specificity, positive predictive value and accuracy in comparison with SD-CCTA (98%, 91% and 99% vs 95%, 80% and 95%, respectively, p<0.0001). Moreover, HD-CCTA showed a better agreement versus ICA for calcified plaques in comparison with SD-CCTA (83% vs 53%, p<0.0001). In a patient-based analysis HD-CCTA showed a higher specificity and accuracy in comparison with SD-CCTA (91% and 98% vs 46% and 92%, respectively, p<0.01). No differences were found in terms of radiation exposure between the two groups. Conclusions: Improved evaluability and accuracy mainly is seen in calcified coronary artery lesions in HD-CCTA in comparison with SD-CCTA suggesting a potential role of this technology in high-risk CAD patients

    Aspirin worsens exercise performance and pulmonary gas exchange in patients with heart failure who are taking angiotensin-converting enzyme inhibitors

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    Pulmonary function abnormalities participate in causing exercise disability in patients with congestive heart failure (CHF). Impaired pulmonary gas transfer is one of these abnormalities. Angiotensin-converting enzyme (ACE) inhibitors improve diffusion for carbon monoxide and exercise capacity, an effect that is seemingly mediated through prostaglandin activation because it is inhibited by cyclooxygenase blockade with aspirin. This suggests the possibility that aspirin may disturb the pulmonary function and exercise ability in CHF, at least in those patients who are taking ACE inhibitors. This study was aimed at probing this hypothesis

    Ruolo dell’imaging multimodale nei pazienti candidati ad impianto di valvola aortica percutanea

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    Aortic stenosis is a common disorder. Aortic valve replacement is indicated for symptomatic patients with severe aortic stenosis, as the prognosis of untreated patients is poor. However, despite aortic valve replacement can produce dramatic benefit in the setting of aortic stenosis, morbidity and mortality associated with surgery has fostered a search for alternatives. Transcatheter aortic valve replacement is a novel method to treat selected high-risk patients with aortic stenosis. Patient screening and anatomic measurements of the aortic root, aortic cusp heights, and the distance between aortic annulus and coronary ostia, as well as the evaluation of coronary arteries and peripheral arterial disease are of great importance to ensure procedural success . This review outlines the evolving role of noninvasive multimodality imaging, including echocardiography, multidetector computed tomography and cardiac magnetic resonance, in support of transcatheter aortic valve implantation, and describes how the multimodality imaging approach is crucial in this clinical setting

    An unusual case of coronary fistula diagnosed by multidetector computed tomography

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    We present a case of a 82-year-old hypertensive woman who underwent multidetector computed tomography angiography because of chest pain, with detection of a large coronary fistula that originated from the anastomosis between left anterior descending coronary artery and posterior descending artery, in correspondence with the left ventricular apex, and drained into the right atrium and the proximal portion of the right coronary arter
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