56 research outputs found
Video assisted anal fistula treatment (VAAFT): Analysis of the results achieved in the Mendrisio hospital
No full text
Pure H2 production by methane oxy-reforming over Rh-Mg-Al hydrotalcite-derived catalysts coupled with a Pd membrane
No full textRh-Mg-Al hydrotalcites were synthesized by coprecipitation, then calcined and reduced to obtain catalysts active in the oxy-reforming of methane. In particular, it was shown that an increased activity can be obtained by reducing the Mg/Al ratio or increasing the Rh amount. In addition, the influence of pellet dimension and catalyst amount at same contact time was demonstrated to be negligible thanks to the characteristics of oxy-reforming which allows to work at low contact times without a sharp temperature rise. Moreover, a newly developed thermal treatment of the synthesized hydrotalcite was able to provide an active catalyst with an increased amount of reduced Rh over its surface, which provided very good performances. Finally, a hydrogen-selective Pd-membrane was integrated after the oxy-reforming and was able to separate H2 from the outlet mixture providing pure hydrogen in different conditions with high recoveries
Methane oxy-reforming coupled with a water gas shift membrane reactor for pure hydrogen production
No full textA study of CO2 hydrogenation over Ni-MgAlOx catalysts derived from hydrotalcite precursors
No full textNi/Mg/Al mixed oxides have been prepared by decomposing corresponding layered double hydroxides of the hydrotalcite family. XRD, FTIR and UV–vis–NIR analyses show that prepared materials are constituted by a rock-salt type Mg1−xNixO solid solution with Al3+ in tetrahedral interstices of the cube close packing of oxide anions. When activated at sufficiently high temperature, they convert into optimal size supported Ni metal catalysts which show very active and selective for CO2 methanation. Catalytic data show that these materials are more active at low temperature than Ni/γ-Al2O3 catalysts, with a comparable enhanced activity with respect to Ni/La2O3-Al2O3 ones. A role of basic oxides as activating components can be envisaged and related to the strength of the adsorption of CO2 on the “support” likely forming surface (bi)carbonates as active species. Activation energies and reactions orders have been calculated by flow reactor studies in differential reactor conditions. IR spectroscopy data show that carbon dioxide adsorbs on the reduced catalyst in the form of hydroxycarbonates, that convert at higher temperature in carbonates and strongly adsorbed linear and bridging carbonyl species on metallic nickel. The formation of surface CHx species is also evident
Video-Assisted Anal Fistula Treatment (VAAFT) for complex anorectal fistula: efficacy and risk factors for failure at 3-year follow-up
No full textBackground: The aim of this study was to assess the 3-year objective and subjective outcomes of patients with complex anorectal fistula treated with Video-Assisted Anal Fistula Treatment (VAAFT). Furthermore, we evaluated the risk factors associated with recurrence. Methods: All consecutive patients with complex anorectal fistula who underwent VAAFT in Beata Vergine Hospital of Mendrisio, Switzerland, from January 2013 to January 2016, were enrolled. Patients with suspicion or diagnosis of Crohn’s disease, malignancy, previous history of radiotherapy or radical pelvic surgery were excluded. Preoperative clinical assessment based upon medical history, physical examination and endosonography, was performed in all patients. Data regarding subjective outcomes (the Patient Global Impression of Improvement, patient satisfaction scores and Wexner score), objective cure rate (absence of fistula at clinical examination), and adverse events were collected during follow-up. Uni and multivariate analysis were performed to investigate outcomes. Results: One hundred and four patients had VAAFT. At 3-year follow-up, 96 patients (92.3%) were available for the evaluation. At 3 years after surgery, 81 of 96 patients (84.4%) declared themselves cured (p = 0.60). Similarly, at 3-year evaluation, 80 of 96 patients (83.3%) were objectively cured (p = 0.52). No serious intraoperative or postoperative complications were reported. All recurrences were treated with a repeat VAAFT procedure resulting in a complete healing. Uni and multivariate analysis of variables potentially involved in the failure of VAAFT showed that age ≥ 50 years was the only factor associated at risk of recurrence. Conclusions: VAAFT is a highly effective safe procedure for the treatment of anorectal fistula, with a low recurrence rate at 3-year follow-up. However, our study demonstrated that age ≥ 50 years is a risk factor for failure of VAAFT
Nocturnus (CIL V, 4287) : il doppio Attis-Plutone e Noctulius suo doppio
No full textDepto. de Filología ClásicaFac. de FilologíaTRUEpu
Video Assisted Anal Fistula Treatment (VAAFT) for Treating a Complex Posttraumatic Anal Fistula: Case Report
No full textSchwann cells synthesize alpha 7 beta 1 integrin which is dispensable for peripheral nerve development and myelination
No full textDefects in laminins or laminin receptors are responsible for various neuromuscular disorders, including peripheral neuropathies. Interactions between Schwann cells and their basal lamina are fundamental to peripheral nerve development and successful myelination. Selected laminins are expressed in the endoneurium, and their receptors are developmentally regulated during peripheral nerve formation. Loss-of-function mutations have confirmed the importance and the role of some of these molecules. Here we show for the first time that another laminin receptor, alpha7beta1 integrin, previously described only in neurons, is also expressed in Schwann cells. The expression of alpha7 appears postnatally, such that alpha7beta1 is the last laminin receptor expressed by differentiating Schwann cells. Genetic inactivation of the alpha7 subunit in mice does not affect peripheral nerve formation or the expression of other laminin receptors. Of note, alpha7beta1 is not necessary for basal lamina formation and myelination. Nonetheless, these data taken together with the previous demonstration of impaired axonal regrowth in alpha7-null mice suggest a possible Schwann cell-autonomous role for alpha7 in nerve regeneration
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