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    Clinical approach in periodontal diseases associated with oral diseases

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    Periodontal diseases may have non bacterial causes, such as several systemic diseases or adverse drug reactions. When those diseases involve periodontal tissues, oral hygiene usually becomes difficult and individual inflammatory reaction against plaque may be affected. Aim of this study is to analyse pathogenetical and clinical peculiarities of some diseases frequently encountered in clinical practice. Relationships between systemic diseases and associated periodontal diseases are also outlined. The management of medical therapies combined with specific periodontal therapy complete the exposure. Finally the Authors stress the importance of controlling acute inflammation and of a strict periodontal follow-up to achieve an adequate clinical contro

    Uso della Claritromicina RM in chirurgia orale : studio comparativo

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    Polymicrobial oral infections are influenced by anatomy and histology of oral cavity, interactions with external environment and mutual relationships among resident microbial species. The knowledge of pathological mechanisms, pathogens location and epidemiological data about antibiotic resistance may support empirical planning of antibiotic therapy. A wide spectrum together with favourable pharmacokinetics, oral tissue tropism and good tolerance are the main selective criteria to choose antibacterial drugs. Aim of this preliminary study is a retrospective evaluation of wound healing and tolerance in three groups of patients submitted to oral biopsies. Patients were divided according to their risk (systemic, local, operative) and the therapeutic effects of clarithromycin RM were compared with amoxicillin-clavulanic acid and a placebo. The preliminary results showed good tolerance and considerable improvement in wound healing in the clarithromycin RM group. Clinical implications of these data suggest a widening of antibacterial drug options facing increasing bacterial resistance and individual sensibilization to antibiotics

    Parodontopatie correlate a patologie orali : approcci clinico-terapeutici

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    Periodontal diseases may have non bacterial causes, such as several systemic diseases or adverse drug reactions. When those diseases involve periodontal tissues, oral hygiene usually becomes difficult and individual inflammatory reaction against plaque may be affected. Aim of this study is to analyse pathogenetical and clinical peculiarities of some diseases frequently encountered in clinical practice. Relationships between systemic diseases and associated periodontal diseases are also outlined. The management of medical therapies combined with specific periodontal therapy complete the exposure. Finally the Authors stress the importance of controlling acute inflammation and of a strict periodontal follow-up to achieve an adequate clinical control

    Accuratezza diagnostica della Cone Beam Computed Tomography (CBCT) nel rilevare l’invasione ossea del carcinoma orale = Diagnostic accuracy of cone beam computed tomography (CBCT) to detect bone invasion by oral carcinoma

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    Obiettivi Analizzare l’accuratezza diagnostica della Cone Beam Computed Tomography (CBCT) rispetto ad altre metodiche d’immagine nel rilevare l’invasione ossea da carcinoma squamocellulare orale (Oral Squamous Cell Carcinoma, OSCC). Materiali e metodi La revisione della letteratura è stata condotta su studi in lingua inglese indicizzati in PubMed dal 1990 al 2014. Sensibilità, specificità e rapporto di verosimiglianza positivo (RV+) e negativo (RV–) sono stati calcolati per ogni studio. Dei 61 articoli raccolti, 7 soddisfacevano i criteri di inclusione. Risultati e conclusioni I dati analitici mostrano valori di RV+ e RV–, rispettivamente, di 14,4 e 0,35 per la CT (Computed Tomography); 37,9 e 0,24 per la MRI (Magnetic Resonance Imaging); 27,8 e 0,10 per la CBCT; 25,5 e 0,06 per la SPECT (Single- Photon Emission Computed Tomography); 37,0 e 0,31 per la MSCT (Multi- Slice Computed Tomography); 4,8 e 0,36 per l’ortopantomografia (OPT). Il grado di evidenza scientifica a oggi disponibile è debole. Ulteriori studi con impostazione metodologica uniforme sono necessari per definire meglio l’impatto della CBCT sul processo decisionale clinico.OBJECTIVES. The aim of this study. generawas to analyze the diagnostic accuracy of Cone Beam Computed Tomography (CBCT) with respect other imaging methods for the detection of bone tissue invasion by Oral Squamous Cell Carcinoma (OSCC). MATERIALS AND METHODS. A literature review was carried out of English language studies in PubMed between 1990 and 2014. Sensitivity, specificity, positive (LR+) and negative (LR) likelihood ratio were calculated for each study. Of the 61 collected articles, 7 fulfilled the inclusion criteria. RESULTS AND CONCLUSIONS. The analytic data showed values of LR+ and LR of 14.4 and 0.35 for CT (Computed Tomography), 37.9 and 0.24 for MRI (Magnetic Resonance Imaging), 27.8 and 0.10 for CBCT, 25.5 and 0.06 for SPECT (Single-Photon Emission Computed Tomography), 37.0 and 0.31 for MSCT (Multi-Slice Computed Tomography), 4.8 and 0.36 for OPT (Orthopantomography), respectively. The level of scientific evidence available today is low. Further studies with uniform methodological approach are needed, to better define the impact of CBCT on clinical decision-making
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