57 research outputs found
Formazione e presenza di trialometani (THM) nelle acque di piscina
No full textnel lavoro vengono descritti gli effetti derivanti dalla disinfezione con composti del cloro nelle acqu
A procedure for determining plasmatic trichloroacetic acid in human subjects exposed to chlorinated solvents at environmental levels
No full textAn improved gas-chromatographic procedure was developed and tested for evaluating plasmatic trichloroacetic acid (TCA), a terminal metabolite of trichloroethylene and tetrachloroethylene, pollutants widely diffused in the environment. It determines the chloroform produced by TCA thermal decarboxylation. The specificity, sample preservation, decarboxylation phase, qualitative and quantitative analysis of chloroform in the static head space have been discussed and documented. The sensitivity of the procedure (2 μg/L plasma) is adequate to the environmental exposure. Good accuracy and precision is possible
Human environmental exposure to trichloro- and tetrachloroethylene from water and air in Milan, Italy
No full textAnnual consumption of trichloro- (TRI) and tetrachloroethylene (PER) in the Milan city area is estimated to be between 1,500 and 2,000 tons. Improper use and disposal of TRI and PER for many years have led to a serious pollution of groundwater, which is used untreated by 1,750,000 inhabitants through the municipal aqueduct. Two separate sub-areas of the city were considered, namely zone A (TRI and PER concentrations: 80 and 20 μg/L, respectively) and zone B (12 and 4 μg/L). Trento, a 70,000 inhabitants town of northern Italy, supplied with drinking water not contaminated with TRI and PER, was chosen as a control (zone C). Atmospheric levels of TRI and PER were also measured: TRI concentrations were similar in zones A and B (7.6 and 7.1 mg/m3), but higher levels of PER were found in zone A (14.8 vs 9.5 μg/m3), where many dry-cleaning laundries are located. In human subjects from the three zones, the total exposure to TRI and PER was biologically evaluated by measuring the plasmatic level of their metabolite trichloroacetic acid (TCA). Median plasmatic TCA levels were 38.2 μg/L in zone A, 19.0 in zone B and only 7.5 in the control zone. The observed differences were highly significant, and unrelated to sex, age, body weight, residence, and the amount of water consumption
Metabolites of chlorinated solvents in blood and urine of subjects exposed at environmental level
No full textAfter a two-level selection, 141 blood donors living in Milan, Italy, were analyzed for their content of plasma and urinary trichloroacetic acid (TCA) and trichloroethanol (TCE). Environmental levels of exposure to trichloroethylene (TRI) and tetrachloroethylene (PER) through drinking water and air were also measured. The plasma TCA levels were in the range of previously found concentrations. Relationships among plasma and urinary metabolites were found and discussed
Comparazione di metodi per la valutazione della mutagenicità delle acque potabili in Lombardia
No full textGruppo Scientifico Italiano Studi e Ricerch
Ricerche sulle mutagenicità in acque potabilizzate provenienti da due laghi del Nord Italia
No full text- …
