556 research outputs found
Card from Monsignor G. Sinibaldi to Hagan
No full textHolograph card from Monsignor G. Sinibaldi, secretary to the Congregation for Seminaries and Universities, to Hagan, introducing his nephew Giacomo Modesti; asking to assist him
Correction to: A T-junction device allowing for two simultaneous orthogonal views: application to bubble formation and break-up (Microfluidics and Nanofluidics, (2018), 22, 8, (85), 10.1007/s10404-018-2101-1)
No full textThe article ‘A T-junction device allowing for two simultaneous orthogonal views: application to bubble formation and break-up’, written by Davide Caprini, Giorgia Sinibaldi, Luca Marino, Carlo Massimo Casciola was originally published electronically on the publisher’s internet portal (currently SpringerLink) on 30 July 2018 without open access
Letter from G. Palombi to Monsignor Sinibaldi
No full textHolograph letter from G. Palombi, engineer, Salita S. Nicola da Tolentino 1B, Rome, to Monsignor Sinibaldi (Rome), asking him to mediate between him and the rector of the Irish College who does not respond to his recent correspondence concerning outstanding bills. Attaching a memorandum explaining the facts (not extant); planning to inform all cardinals and rectors of colleges in that way. (Covering letter not extant.
Vascular network organization in posterior atrophic human mandible: a guide for an appropriate surgical approach
No full textBackground: The bone vascularity plays a key role for a successful surgical approach during implant placement on the posterior
atrophic lower jawbone. Although, some very old references are reported on animal studies, to the author best knowledge no
data are present in literature regarding this subject.
Aim/Hypothesis: The aim of this work was to evaluate the vascular arrangement in posterior, edentulous, atrophic mandibular
crests on humans
Explanation of the stability of thermophilic proteins based on unique micromorphology
No full textTwo mesophilic/thermophilic variants of the G-domain of the elongation factor Tu were studied via molecular dynamics simulations. By analyzing the simulation data via the Voronoi space tessellation, we have found that the two proteins have the same macromolecular packing, while the water-exposed surface area is larger for the thermophile. A larger coordination with water is probably due to a peculiar corrugation of the exposed surface of this species. From an enthalpic point of view, the thermophile shows a larger number of intramolecular hydrogen bonds, stronger electrostatic interactions, and a flatter free-energy landscape. Overall, the data suggest that the specific hydration state enhances macromolecular fluctuations but, at the same time, increases thermal stability
Swimming and rafting of E.coli microcolonies at air–liquid interfaces
No full textThe dynamics of swimming microorganisms is strongly affected by solid-liquid and air-liquid interfaces. In this paper, we characterize the motion of both single bacteria and microcolonies at an air-liquid interface. Both of them follow circular trajectories. Single bacteria preferentially show a counter-clockwise motion, in agreement with previous experimental and theoretical findings. Instead, no preferential rotation direction is observed for microcolonies suggesting that their motion is due to a different physical mechanism. We propose a simple mechanical model where the microcolonies move like rafts constrained to the air-liquid interface. Finally, we observed that the microcolony growth is due to the aggregation of colliding single-swimmers, suggesting that the microcolony formation resembles a condensation process where the first nucleus originates by the collision between two single-swimmers. Implications of microcolony splitting and aggregation on biofilm growth and dispersion at air-liquid interface are discussed
A new tumour associated antigen of non-small cell lung cancer: Tumour liberated proteins (TLP) - A possible new tumor marker
No full textTLP (Tumour Liberated Proteins) is a 214 kDa protein, isolated from lung cancer tissue and synthetic nonapeptide CSH-275 is a major epitope identified on a 100 kDa TLP fragment and used to create antibodies in rabbit (antiserum termed CSH-419). CSH-419 antiserum, labelled or conjugated as necessary, was used to detect TLP on sera from NSCLC patients by a new ELISA test set up as a 1 step sandwich format test. this ELISA was performed on sera from 534 individuals. TLP was detected in 53.1% of NSCLC patients, with a 0% response in patients with cancers other than NSCLC, 7.6% response in unknown blood donors, and 17.4% response in patients with chronic lung diseases correlated with an elevated risk for lung cancer. TLP was particularly present in early stages of disease: 75% in stage I, 56% in stage II and II and 45% in stage IV. The presence of TLP antigen in sera from NSCLC patients indicates that TLP could represent an useful tumour marker
Activity and mechanism of the antioxidant properties of cyanidin-3-O-beta-glucopyranoside
No full textIn the present study, the antioxidant activity the interaction with reactive oxygen species and the redox potential of cyanidin-3-O-beta-glucopyranoside (C-3-G), the main anthocyanin present in juice of pigmented oranges, were evaluated in detail. C-3-G effects on low density lipoproteins (LDL) oxidation induced by 40 muM Cu2+ at a pH of 7.4 were compared with those of resveratrol and ascorbic acid, two other natural antioxidants. All cyanidin-3-O-beta-glucopyranoside concentrations used (1, 2, 5, 10, 20, 50, 100 and 200 muM) inhibited malondialdehyde (MDA) generation (an index of lipid peroxidation), the inhibition being significantly higher than that obtained with equal concentrations of resveratrol and ascorbic acid (IC50=6.5 muM for C-3-G, 34 muM for resveratrol and 212 muM for ascorbic acid). Experiments of LDL oxidation performed at a pH of 5.0 or 6.0 showed that C-3-G antioxidant activity is not influenced by pH variations between 5.0 and 7.4. This suggests that metal chelation, exerted by C-3-G through the eventual dissociation of its phenolic groups, plays a minor role in its protective mechanism. The presence of C-3-G produced significantly higher protective effects of pigmented orange juice (obtained from Moro cultivar) with respect to blond orange juice, when tested on copper-induced LDL oxidation. The evaluation of the direct interaction with reactive oxygen species (H2O2, O--(2), OH.), demonstrated that C-3-G is quickly oxidized by these compounds and it is, therefore, a highly efficient oxygen free radical scavenger. The powerful C-3-G antioxidant activity is in excellent agreement with the very negative redox potential (-405 mV), determined through direct current cyclic voltammetry measurements. On the basis of these results, C-3-G should be considered as one of the most effective antioxidants that can be assumed with dietary plants; therefore, pigmented oranges represent a very relevant C-3-G source because of the high content of this anthocyanin in their juice
"Thin layer chromatographic and "in situ" spectrophotometric determination of products in solid-solid thermal reaction"
No full text"Preparation and characterization of cobalt(III)bipyridine and phenantrholine complexes"
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