3 research outputs found

    Presence of thyroid-associated ophthalmopathy in Hashimoto’s thyroiditis

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    AIM:To determine the prevalence of ophthalmopathy in Hashimoto’s patients and to make a comparison in subgroups of patientsMETHODS:The study involved 110 Hashimoto’s thyroiditis patients and 50 control subjects attending to the endocrinology department of the hospital. Subgroup classification of patientswas made as euthyroid, subclinic and clinic in Hashimato’s thyroiditis. All patients were evaluated by a single experienced ophthalmologist for the prevalence and characteristics of eye signs.RESULTS: The overall prevalences of eye changes were 22.7% (25 patients) in patients and 4% (2 persons) in control subjects respectively (P=0.002). In patients the most common symptom was retrobulbar eye pain with or without any eye movement. Thirteen patients had significant upper eyelid retraction (11.8%). Six patients had eye muscle dysfunction as reduced eye movements in up gaze. In control patients one person had proptosis and another had lid retraction. The clinical activity score and classification of the ophthalmopathy did not show any significant differences among subgroups.CONCLUSION:The eye signs were mostly mild (22.7%) and the most common eye sign was the presence of upper eyelid retraction (11.8%). Additionally six patients had eye muscle dysfunction as reduced eye movements in up gaze. Therefore we recommend to make a routine ophthalmic examination in Hashimoto’s thyroiditis patients in order not to omit the associated ophthalmopathy

    Effect of drainage conditions on CPT resistance of silty sand: physical model and field tests

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    The influence of drainage conditions on cone penetration test (CPT) resistance and the excess pore pressure during cone penetration in sand and silty sand are examined using field and physical model tests. Drainage can generally occur in saturated clean sand and silty sand under certain conditions. This work aims to understand and explain the effect of sand and silty sand drainage conditions on CPT resistance and pore pressure through the coefficient of consolidation (c h) and penetration rate (v). The physical model test results indicate the significant effect of excess pore pressures and their dissipation rates, depending on the coefficient of consolidation (silt content) and the penetration rate on cone resistance. For the same relative density, normalized CPT resistance decreases as there is a reduction in c h (or an increase in silt content) or an increase in penetration rate. The difference in CPT resistance in silty sand is attributed to drainage conditions. Finally, the results revealed in this study and the field test data reported in the literature were combined to develop an equation for the effect of drainage conditions on excess pore water pressure and CPT resistance. © 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature

    The mid-Cenozoic succession and evolution of the Mut basin, southern Turkey, and its regional significance

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    The hitherto poorly known Mut basin occupies a position that is critical to our understanding of the later Cenozoic history of south central Turkey. The biostratigraphic and sedimentological study reported here reveals an extended and complex pattern of basin evolution and enables the history of this basin to be compared in detail with that of adjacent south Turkish basins. The oldest basin fill deposits are demonstrated to be Oligocene to earliest Miocene in age and comprise alluvial redbeds, thick lacustrine deposits and thin lagoonal sediments mainly supplied from northern (Tauride) sources This mainly terrestrial megasequence resulted from an early Oligocene phase of crustal extension, leading to rapid "trap-door" subsidence and the formation of narrow E-W trending troughs. This phase was terminated by a minor marine incursion and through reactivation of basement faults during renewed extension in the earliest Miocene. The overlying Miocene succession, thus, rests wit h local angular discordance upon tilted and gently deformed Oligocene (and older) rocks. Subsequent subaerial erosion created an irregular pre-Burdigalian palaeotopography that strongly influenced the nature, thickness and distribution of the early Miocene basin fill. In palaeotopographic depressions, the Miocene sequence commences with alluvial fan, braidplain and meander belt redbeds formed in river systems that flowed mainly south and southeast. These pass up (and laterally) into more extensive lagoonal and shallow marine mixed clastic/carbonate units yielding late Burdigalian to early Langhian microfaunas, marking the inception of the main Miocene marine transgression in this area. Episodic northwards marine advance led to isolation of the northerly source of siliciclastic detritus and resulted in periodic onlap of mid- to inner-shelf fine-grained carbonates (with thin clastic intercalations) that include isolated coralgal build-ups, calcarenite mounds and sand-waves. At the peak of Miocene transgression (mid-Serravallian), thick reefal limestones were deposited far to the north and also formed on top of basement highs forming the southern and eastern flanks of the basin. Significant influxes of coarse and fine siliciclastics from the north attest to periodic progradational events that are more conspicuous and protracted in the late Serravallian and Tortonian. However, muddy deeper shelf conditions prevailed throughout the middle Miocene in the central part of the basin, while stronger currents and unstable slopes characterise the constricted marine strait in the southeast of the basin near Silifke. In terms of their sequentia l arrangement, palaeoenvironmental and tectonic evolution the Oligo-Miocene sediments of the Mut basin closely resemble coeval sequences in the adjacent Ecemis-Aktoprak and Karsanti-northern Adana basins and share a similar history, involving complex interplay between regional tectonics and eustasism. Deeper water Oligo-Miocene sequences in the 'outboard troughs', such as the southern Adana basin and the Kyrenia-Misis-Andirin complex, yield more subtle signatures of these tectonic and eustatic events. The differences between these basins are attributable to the influence of regional kinematic elements generated during the reorganisation of plate boundaries in the northeast Mediterranean that followed final suturing of the Arabian and Anatolide plates in the mid-Cenozoic. © 2004 Elsevier B.V. All rights reserved.The first author is grateful for financial support provided by the Research Fund of Cukurova University and for logistical assistance by members of Maden Tetkik ve Arama Genel Mudurluğu, Ankara. Thanks are due to Peter Greatbatch and David Wilde (Keele University) for their help in preparing diagrams. We are also grateful to Prof. Dr. E. Gökten, Dr. G. A. George and Prof. S. Burley who provided important and constructive comments on earlier versions of this paper
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