3,701 research outputs found

    Reversal of brain metabolic abnormalities following treatment of AIDS dementia complex with 3'-azido-2',3'-dideoxythymidine (AZT, zidovudine): a PET-FDG study.

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    Brain glucose metabolism was evaluated in four patients with acquired immunodeficiency syndrome (AIDS) dementia complex using [18F]fluorodeoxyglucose (FDG) and positron emission tomography (PET) scans at the beginning of therapy with 3'-azido-2',3'-dideoxythymidine (AZT, zidovudine), and later in the course of therapy. In two patients, baseline, large focal cortical abnormalities of glucose utilization were reversed during the course of therapy. In the other two patients, the initial PET study did not reveal pronounced focal alterations, while the post-treatment scans showed markedly increased cortical glucose metabolism. The improved cortical glucose utilization was accompanied in all patients by immunologic and neurologic improvement. PET-FDG studies can detect cortical metabolic abnormalities associated with AIDS dementia complex, and may be used to monitor the metabolic improvement in response to AZT treatment

    Pituitary microadenomas: a PET study.

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    Twenty cases of surgically verified pituitary microadenoma (17 with Cushing disease and three with acromegaly) were studied with positron emission tomography (PET) with use of fluorine-18-2-fluorodeoxyglucose (FDG). The diagnostic results were compared with those of other modalities, namely, computed tomography (CT), magnetic resonance (MR) imaging, and, in the cases of Cushing disease, simultaneous bilateral inferior petrosal sinus sampling (SIPS). The PET results showed 12 positive readings and one questionable reading, compared with seven positive readings and one questionable reading for CT (18 cases studied) and 13 positive and two questionable MR imaging readings. PET complemented MR imaging, in the sense that five of the positive PET readings were negative or questionable at MR imaging. PET studies of 20 healthy control subjects showed no false-positive cases, whereas other studies of healthy subjects with contrast material-enhanced CT and MR imaging have yielded, respectively, 20% and 15% positive readings, with findings suggestive of silent or occult adenomas

    Self-compression of 4.9 µm pulses to sub-40 fs with 2 mJ energy in Zinc Sulfide

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    Nonlinear self-compression of few-cycle multi-mJ pulses at 4.9 µm in ZnS is presented. 80 fs input pulses are compressed to 37 fs with 2.1 mJ energy at a 1 kHz repetition rate. © 2024 The Author(s

    Constructing reliable parametric images using enhanced GLLS for dynamic SPECT

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    Author name used in this publication: (David) Dagan Feng2008-2009 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishedVoR allowe

    Correction to: Chamoun et al., Bacterial pathogenesis and interleukin-17: interconnecting mechanisms of immune regulation, host genetics, and microbial virulence that influence severity of infection

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    Chamoun MN, Blumenthal A, Sullivan MJ, Schembri MA, Ulett GC. 2018. Bacterial pathogenesis and interleukin-17: interconnecting mechanisms of immune regulation, host genetics, and microbial virulence that influence severity of infection. Critical Reviews in Microbiology. https://doi.org/10.1080/1040841X.2018.1426556. When the above article was first published online, the below three corrections were missed. The author ‘Antje Blumenthal’ was wrongly affiliated to the affiliation “cSchool of Chemistry and Molecular Biosciences, and Australian Infectious Disease Research Centre, The University of Queensland, Brisbane, Australia”. Now this affiliation has been removed for this author. The affiliation ‘bTranslational Research Institute, The University of Queensland Diamantina Institute, Woolloongabba, Australia’ of the author ‘Antje Blumenthal’ should read ‘bThe University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia’. In Table 3, the sentence ‘Benefit of manipulating IL-17 levels to improve immunization strategies M. tuberculosis’ should read “Benefit of manipulating IL-17 levels to improve immunization strategies against M. tuberculosis”.No Full Tex

    Non-invasive extraction of physiological parameters in quantitative PET studies using simultaneous estimation and cluster analysis

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    Author name used in this publication: Dagan FengRefereed conference paper2000-2001 > Academic research: refereed > Refereed conference paperVersion of RecordPublishedVoR allowe

    Segmentation of brain structures using PET-CT images

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    Author name used in this publication: Michael FulhamAuthor name used in this publication: Dagan FengRefereed conference paper2007-2008 > Academic research: refereed > Refereed conference paperVersion of RecordPublishedVoR allowe

    Adaptive fuzzy clustering in constructing parametric images for low SNR functional imaging

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    Author name used in this publication: Michael FulhamAuthor name used in this publication: Dagan FengRefereed conference paper2008-2009 > Academic research: refereed > Refereed conference paperVersion of RecordPublishedVoR allowe

    Development of an electronic medical report delivery system to 3G GSM mobile (cellular) phones for a medical imaging department

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    Author name used in this publication: Dagan FengAuthor name used in this publication: Michael FulhamRefereed conference paper2007-2008 > Academic research: refereed > Refereed conference paperVersion of RecordPublishedVoR allowe
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