1,040 research outputs found

    Flow Visualization and Heat Transfer Characteristics of Droplet Train Obliquely Impinging on a Moving Hot Solid

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    The spray cooling of moving hot solids is widely performed in the steel industry. Understanding flow and heat transfer when droplets impinge on moving hot solids is important. By simultaneous visualization with flash photography and temperature measurement using thermography, the flow and heat transfer of a droplet train obliquely impinging on a moving solid at high temperatures was experimentally investigated. A rectangular test piece (SUS303) was heated to 500 °C at a moving velocity of 0.25–1.5 m/s. The test liquid was water at approximately 25 °C. The pre-impact droplet diameter, impact velocity, and inter-spacing between two successive droplets were 0.69 mm, 2.2 m/s, and 2.23 mm, respectively. The tilt and torsional angles were 50° and −30–60°, respectively. No coalescence of droplets was observed; the droplets deformed independently on the moving solid, even though the torsional angle generated a velocity component along the width of the solid. The surface temperature of solid after droplet impingements depended on the experimental conditions. Wavy temperature profile was obtained when the moving distance of solid was large during two successive collisions. The temperature changed continuously for the small distances. In this regard, a simple model considering droplet movement, collisional deformation behavior, and solid migration can explain this phenomenon by the overlap of the cooling regions of the droplets. Furthermore, experimental and numerical analyses show that the heat removal rate of individual droplets is constant at approximately 12.5 MW/m² and depends on the total contact time when multiple droplets collide

    Chlorpromazine cooperatively induces apoptosis with tyrosine kinase inhibitors in EGFR-mutated lung cancer cell lines and restores the sensitivity to gefitinib in T790M-harboring resistant cells

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    主査:西尾和人 教授  学内授与番号:医第1394号 Ryosuke Fujiwara, Yasuhiro Taniguchi, Shinya Rai, Yoshio Iwata, Aki Fujii, Ko Fujimoto, Takahiro Kumode, Kentaro Serizawa, Yasuyoshi Morita, J. Luis Espinoza , Hirokazu Tanaka, Hitoshi Hanamoto, Itaru Matsumura "Chlorpromazine cooperatively induces apoptosis with tyrosine kinase inhibitors in EGFR-mutated lung cancer cell lines and restores the sensitivity to gefitinib in T790M-harboring resistant cells"Biochemical and Biophysical Research Communications, Volume 626, 20 October 2022, Pages 156-166 https://doi.org/10.1016/j.bbrc.2022.08.010 掲

    Chlorpromazine cooperatively induces apoptosis with tyrosine kinase inhibitors in EGFR-mutated lung cancer cell lines and restores the sensitivity to gefitinib in T790M-harboring resistant cells

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    近畿大学Kindai University博士(医学)主査:西尾和人 教授  学内授与番号:医第1394号 Ryosuke Fujiwara, Yasuhiro Taniguchi, Shinya Rai, Yoshio Iwata, Aki Fujii, Ko Fujimoto, Takahiro Kumode, Kentaro Serizawa, Yasuyoshi Morita, J. Luis Espinoza , Hirokazu Tanaka, Hitoshi Hanamoto, Itaru Matsumura "Chlorpromazine cooperatively induces apoptosis with tyrosine kinase inhibitors in EGFR-mutated lung cancer cell lines and restores the sensitivity to gefitinib in T790M-harboring resistant cells"Biochemical and Biophysical Research Communications, Volume 626, 20 October 2022, Pages 156-166 https://doi.org/10.1016/j.bbrc.2022.08.010 掲載doctoral thesi

    Erratum: The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition (Proceedings of the National Academy of Sciences of the United States of America (2020) 117 (4180-4187) DOI: 10.1073/pnas.1913481117)

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    Correction for “The histone demethylase JMJD2B regulates endothelial-to-mesenchymal transition,” by Simone F. Glaser, Andreas W. Heumüller, Lukas Tombor, Patrick Hofmann, Marion Muhly-Reinholz, Ariane Fischer, Stefan Günther, Karoline E. Kokot, David Hassel, Sandeep Kumar, Hanjoong Jo, Reinier A. Boon, Wesley Abplanalp, David John, Jes-Niels Boeckel, and Stefanie Dimmeler, which was first published February 7, 2020; 10.1073/pnas.1913481117 (Proc. Natl. Acad. Sci. U.S.A. 117, 4180-4187). The authors note that Hitoshi Okada should be added to the author list between Karoline E. Kokot and David Hassel. Hitoshi Okada should be credited with providing mice. The corrected author line, affiliation line, and author contributions appear below. The online version has been corrected

    Development of Flow Visualization Measurement Method of Droplet Train Obliquely Impinging on Moving Hot Solid

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    Spray cooling on moving hot solids is widely used in metal heat treatment processes. Understanding coolant droplet collision behavior with moving hot solids is of great importance toward improving heat treatment temperature control technology. Via flash photography, we experimentally investigated the hydrodynamics of droplet train obliquely impinging on a hot moving solid. The test piece was a rectangular steel piece (SUS303) heated to 500°C, 550°C, or 600°C with a moving velocity of 0.5 m/s, 1.0 m/s, or 1.5 m/s. The test liquid was water at approximately 20°C. The pre-impact diameter of droplets, droplet impact velocity, and inter-spacing between every successive two droplets were 0.64 mm, 2.2 m/s, and 1.91 mm, respectively. The tilt angle of the droplet train to the vertical was 50°. No coalescence of droplets was seen—the droplets deformed independently on the moving solid. The measured results of the maximum diameter and the residence time of the droplets agreed well with the empirical formulas that can be used for droplet impact on a stationary solid. It was found that the dynamics of a droplet train impinging on a hot moving solid are the same as the dynamics of a droplet train impinging on a hot stationary solid when the droplets deform independently on a moving solid. Taking advantage of said property such that it is equivalent to the dynamics of a droplet train impinging on a hot stationary solid, we proposed a critical condition for droplet coalescence and experimentally confirmed the validity of the critical condition

    Development of a Method for Evaluating Heat Transfer Characteristics of a Circular Water Jet Impinging on a Moving Flat Plate

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    In metal hot-rolling processes, water jet cooling of a moving hot solid is commonly used for run-out table (ROT) cooling. High-accuracy evaluation of the surface heat flux at jet-impinging areas is important for accurate temperature control to produce high-quality steel plates. Most previous studies on the heat transfer characteristics of jet impingement areas have considered water jet impingement on stationary hot solids; however, the flow conditions are different in ROT cooling because the water jet impinges on moving hot solids. Thus, the estimation of the heat flux at the jet impact zone of a water jet on a moving hot solid is essential. Therefore, we developed a method for evaluating the surface heat flux in the impinging areas of water jet cooling of a moving hot solid. The method was based on the inverse solution of the heat conduction equation, using the measured temperature profile as a boundary condition, such that the heat removal in the jet impinging area was obtained numerically. To demonstrate the validity of our model, we performed cooling experiments on a circular water jet impinging obliquely on a moving hot solid. The experiments were conducted under the following conditions: temperature of the solid made of stainless steel was 300-550 °C, moving velocity of the solid was 0.5-1.0 m/s, jet diameter was approximately 0.31 mm, and water flow rate was 10 ml/min. We confirmed that the model was useful for evaluating the heat flux in the jet impact region

    ERRATA

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    Volume and issue: Vol.6, No.7 (2011)Page: pp.317-322Title: Contribution of Slip and Cleavage in Friction and Wear at (10-14) Surface of Magnesite (MgCO3) CrystalAuthor(s): Kaori Niki, Mai Kobayashi and Hitoshi ShindoVolume and issue: Vol.7, No.1 (2012)Page: pp.8-12Title: Frictional Asymmetry and Wear Pattern Formation by Slip and Cleavage Detected at Directional r {10-14} Face of Calcite (CaCO3)Author(s): Kaori Niki, Mai Kobayashi and Hitoshi Shind

    Letter from John Lancaster, Unit President, A.I.F.D., January 29, 1970

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    Letter from John Lancaster, Chairman, American Institute of Floral Designers (A.I.F.D) addressed to the florists who are interested in attending the Yoke Kuromi Memorial Dinner.This collection contains two photograph albums and material related to Hitoshi "Yoke" Kuromi and Corrine Nobuko Nishimura Kuromi. Subjects in the collection include the Kuromi family, the Gila River incarceration camp, and hot rods, and classic cars

    Letter from John Lancaster, Unit President, A.I.F.D., January 29, 1970

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    Letter from John Lancaster, Unit President, American Institute of Floral Designers (A.I.F.D.), possibly addressed to the Southern California Teleflora Unit about the funeral for Yoke Kuromi.This collection contains two photograph albums and material related to Hitoshi "Yoke" Kuromi and Corrine Nobuko Nishimura Kuromi. Subjects in the collection include the Kuromi family, the Gila River incarceration camp, and hot rods, and classic cars
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