1,720,973 research outputs found

    Allergic rhinitis: A challenge diagnosis

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    AIM: The allergic rhinitis represents one of the ten major causes of ambulatory check-up. The incidence is between 10% to 25% in the general population and, in Italy, is approximately present in 10% of children and 20% of adolescents. The diagnosis of this disease is related to family anamnesis and the presence of several signs and typical symptoms. Regarding the tests used to detect this disease, cutaneous specific IgE (skin prick test) is used as cute reactivity expression. Using nasal specific IgE dosage we analyzed patients affected by rhinitis and its relationship between positive test, gender and age, the relationship between positive test and disease and the better response to diagnosis between the 2 tests performed (i.e., skin prick test and nasal specific IgE). METHODS: We analyzed 125 subjects enrolled consecutively, age range 48-216 months (median 144 months) that performed skin prick test and nasal specific IgE. RESULTS: Looking at the overall subjects, 51 subjects were positive to skin prick test and nasal specific IgE, 23 subjects were positive to skin prick test, 31 subjects were positive to nasal specific IgE, 20 subjects were negative to both tests. Regarding the relationship between tests positive and symptoms we did not find any significant correlation. CONCLUSIONS: Our data suggests that rhinitis diagnosis is quite difficult to perform and the test used to detect this disease needs to be more accurate and precise. Family anamnesis and clinical signs are fundamental in the diagnosis of allergic rhinitis

    Growth curves in pediatrics. Pilot study in a city of south of Italy.

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    AIM: In the past years the body composition assessment in pediatric subjects showed great changes due to the different quality of life and different diet habits. Over-weight and obesity increased tremendously not only in the industrialized societies but also in developing countries. Growth curves developed in the 60s need to be revises in the light of these changes and population specific curves are needed to follow a population with different life style and energy intake. The aim of this study was to evaluate, in a city of South Italy (San Severo), pediatric subjects in order to create growth curves.METHODS: Between May 1999 and October 2000 we evaluated 2,262 subjects: 1,172 (51.8%) males and 1,090 (48.2%) females, age range 6-11 years (mean 8.48 +/- 2.28 years). Height, weight, thoracic circumference and body mass index (BMI) were measured by the same expert operator.RESULTS: Tables and figures for weight, height, thoracic circumferences and BMI at 3 degrees, 50 degrees, 97 degrees centile for age and gender were presented. A comparison between 50 degrees centile for BMI in males and females were also done showing the different development related to gender.CONCLUSIONS: The results obtained underline the importance of an auxologic follow-up of the pediatric subjects in order to evaluate their correct development. The specific growth curves available make it possible to analyze the development of subjects in comparison with the subjects studied for the curves development. Moreover, the importance of the BMI curve and the relationship of the 50 degrees centile in males and females showing the different growth curve related to gender, is underlined

    Overweight and hypertension: longitudinal study in school-aged children.

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    AIM: A continuous increase in overweight has been documented in the paediatric population. The increase occurred in many developed and also developing countries. In the United States prevalence of overweight is 21.5% among African-Americans, 21.8% among Hispanics, and 12.3% among non-Hispanic whites; in Europe, from 10% to 20% in Northern Europe and 20% to as high as 36% in parts of Southern Italy (International Obesity Task Force data). The association between overweight and hypertension in children has been reported. This longitudinal study assessed the prevalence of hypertension and the relationships between gender, overweight, and blood pressure. METHODS: School-based screening was performed in 1.563 children (3-16 years). Age, gender, height, weight and blood pressure were registered every year for 3 subsequent years, in the period 1997-2000. Body mass index (BMI, kg/m2) was calculated and overweight was defined as centile corresponding to BMI = or >25 at 18 years. Blood pressure > 95th centile defined hypertension. RESULTS: The prevalence of elevated blood pressure at first, second and third screenings was 35.1%, 33.8% and 23.9% in males, and 41%, 40.2% and 31.2% in females. The relative risk was significant for overweight subjects. CONCLUSIONS: These results confirm an increasing epidemic of cardiovascular risk in children, as evidenced by an increase in the prevalence of overweight and hypertension. This increase in association with other cardiovascular risk factors that include dyslipidemia, insulin resistance, glucose intolerance, type II diabetes mellitus, suggest the necessity of accurate prevention strategies

    The invisible fat

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    Childhood and adolescence are decisive periods in human life. Body composition and psychological changes determine nutritional requirements as well as eating and physical activity behavior variability. Aims of the present paper are to discuss recent advances in measurements for quantifying total body and regional adiposity, and for mapping adipose tissue distribution in order to evaluate metabolic risk factors in children. Among the new methods available for assessing pediatric body composition, magnetic resonance imaging (MRI) can serve as a reference method for measuring tissue and organ volumes because estimates is reliable independent of age. MRI is the method of choice for calibrating field methods designed to measure adipose tissue and skeletal muscle in vivo and is the only method available for measurement of internal tissues and organs. MRI can be used to validate measures of important molecular level components such as fat measured by dual energy X-ray absorptiometry and bioimpedance analysis. Moreover, the large gap in available information for certain topics makes MRI measurement a dynamic and growing scientific area of body composition investigation

    Metabolic syndrome: a child is not a small adult.

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    Obesity is associated with an increased all-cause mortality rate and even small weight losses can be associated with short-term reduction in risk factors for disease. There is strong evidence that weight loss in obese subjects improves risk factors for diabetes and cardiaovascular diseases. Metabolic syndrome (MS) in adults is defined as a cluster of risk factors for cardiovascular disease and type 2 diabetes mellitus, which includes abdominal obesity, dyslipidemia, glucose intolerance and hypertension. Application of the MS concept in children and adolescents is controversial; in fact no consensus exists on a specific definition for pediatric MS. Lack of consensus is in part due to body evolution associated with childhood and puberty that is related to changes in metabolic and clinical characteristics. The aim of this article is to try to clarify the differences between the MS as a concept and the MS as a diagnostic category, as well as to develop a theory related to its pathophysiology. We comment on the relationship between obesity, regional fat distribution and the MS, and finally we offer some insights into MS methodological approaches for estimating metabolic risk-factor clustering in children and adolescents

    The invisible fat.

    No full text
    Childhood and adolescence are decisive periods in human life. Body composition and psychological changes determine nutritional requirements as well as eating and physical activity behavior variability. Aims of the present paper are to discuss recent advances in measurements for quantifying total body and regional adiposity, and for mapping adipose tissue distribution in order to evaluate metabolic risk factors in children. Among the new methods available for assessing pediatric body composition, magnetic resonance imaging (MRI) can serve as a reference method for measuring tissue and organ volumes because estimates is reliable independent of age. MRI is the method of choice for calibrating field methods designed to measure adipose tissue and skeletal muscle in vivo and is the only method available for measurement of internal tissues and organs. MRI can be used to validate measures of important molecular level components such as fat measured by dual energy X-ray absorptiometry and bioimpedance analysis. Moreover, the large gap in available information for certain topics makes MRI measurement a dynamic and growing scientific area of body composition investigation
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