68,128 research outputs found
Asynchronous H∞ filtering for semi-Markov jump T-S fuzzy systems within partial state delay and deception attack: Applied to aircraft-pilot state estimation
No full textThis article addresses an asynchronous filter design problem within partial state delay and deception attack for a class of discrete-time semi-Markov jump Takagi-Sugeno (T-S) systems which can describe estimation process for human pilot cognitive property. First, the emission probability, which relates to system mode and filtering mode, is introduced to consider the system process with asynchronously observation scheme. Second, state delay-independent condition and state delay-dependent condition de-signed within state delay boundary are proposed under the H & INFIN; performance index & gamma;. Third, the system output signal under deception attack is adopted as the information interference during the transmitted filter process. Through the Lyapunov-Krasovskii approach, stability of the proposed filtering scheme that is mode dependent can be guaranteed. Moreover, the filtering mode is also dynamically changed ac-cording to the prescribed asynchronous formula. A numerical example considered for aircraft-pilot state estimation is used to demonstrate the effectiveness and applicability of our proposed filtering method by obtaining the minimum & gamma;. Experiments show that filter could play a better role in advancing signal estimation in aircraft-pilot state estimation scenario with properties like state delay and deception attack. Also, it contributes to modelling the fully human pilot cognitive decision-making in a human-computer interaction scenario
Pharmacoeconomic analysis of adjuvant oral capecitabine vs intravenous 5-FU/LV in Dukes' C colon cancer: the X-ACT trial
Full text linkOral capecitabine (Xeloda<sup>®</sup>) is an effective drug with favourable safety in adjuvant and metastatic colorectal cancer. Oxaliplatin-based therapy is becoming standard for Dukes' C colon cancer in patients suitable for combination therapy, but is not yet approved by the UK National Institute for Health and Clinical Excellence (NICE) in the adjuvant setting. Adjuvant capecitabine is at least as effective as 5-fluorouracil/leucovorin (5-FU/LV), with significant superiority in relapse-free survival and a trend towards improved disease-free and overall survival. We assessed the cost-effectiveness of adjuvant capecitabine from payer (UK National Health Service (NHS)) and societal perspectives. We used clinical trial data and published sources to estimate incremental direct and societal costs and gains in quality-adjusted life months (QALMs). Acquisition costs were higher for capecitabine than 5-FU/LV, but higher 5-FU/LV administration costs resulted in 57% lower chemotherapy costs for capecitabine. Capecitabine vs 5-FU/LV-associated adverse events required fewer medications and hospitalisations (cost savings £3653). Societal costs, including patient travel/time costs, were reduced by >75% with capecitabine vs 5-FU/LV (cost savings £1318), with lifetime gain in QALMs of 9 months. Medical resource utilisation is significantly decreased with capecitabine vs 5-FU/LV, with cost savings to the NHS and society. Capecitabine is also projected to increase life expectancy vs 5-FU/LV. Cost savings and better outcomes make capecitabine a preferred adjuvant therapy for Dukes' C colon cancer. This pharmacoeconomic analysis strongly supports replacing 5-FU/LV with capecitabine in the adjuvant treatment of colon cancer in the UK
A 2 h periodic variation in the low-mass X-ray binary Ser X-1
No full textSpectroscopy of the low-mass X-ray binary Ser X-1 using the Gran Telescopio Canarias have revealed a ?2 h periodic variability that is present in the three strongest emission lines. We tentatively interpret this variability as due to orbital motion, making it the first indication of the orbital period of Ser X-1. Together with the fact that the emission lines are remarkably narrow, but still resolved, we show that a main-sequence K dwarf together with a canonical 1.4 M? neutron star gives a good description of the system. In this scenario, the most likely place for the emission lines to arise is the accretion disc, instead of a localized region in the binary (such as the irradiated surface or the stream-impact point), and their narrowness is due instead to the low inclination (?10°) of Ser X-1
Review of the book Unbegrenzte moglichkeiten: Amerikanisierung in Deutschland und Frankreich (1900-1933) by Egbert Klautke
No full textDr. Jeff R. Schutts (Douglas College) reviews the book Unbegrenzte Moglichkeiten: Amerikanisierung in Deutschland und Frankreich (1900-1933) by Egbert Klautke (2005).Final article published
Weak solution of (r, (x, u(x)) u′(x))′ = (Fu)′(x) with r(0, u(0))u′(0) = ku(0), r(L, u(L))u′ (L) = hu(L) and k, h are suitable elements of [0, ∞]
No full textAbstractWe consider weak solutions to the nonlinear boundary value problem (r, (x, u(x)) u′(x))′ = (Fu)′(x) with r(0, u(0)) u′(0) = ku(0), r(L, u(L)) u′(L) = hu(L) and k, h are suitable elements of [0, ∞]. In addition to studying some new boundary conditions, we also relax the constraints on r(x, u) and (Fu)(x). r(x, u) > 0 may have a countable set of jump discontinuities in u and r(x, u)−1 ϵ Lq((0, L) × (0, p)). F is an operator from a suitable set of functions to a subset of Lp(0, L) which have nonnegative values. F includes, among others, examples of the form (Fu)(x) = (1 − H(x − x0)) u(x0), (Fu)(x) = ∫xLf(y, u(y)) dy where f(y, u) may have a countable set of jump discontinuities in u or F may be chosen so that (Fu)′(x) = − g(x, u(x)) u′(x) − q(x) u(x) − f(x, u(x)) where q is a distributional derivative of an L2(0, L) function
Letter from R. H. Ford to Commissioner of Indian Affairs, 1860
No full textR. H. Ford (letter author) is the brother of Henry L. Ford. The letter asks if the recently deceased Henry L. Ford was due anything from the government, which would be left to his father, William Ford
Papers of R H Horne
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/69212R.H. "Orion" Horne: Syllabus of Three Lectures on the Undeveloped Characters in Shakespeare's Plays by R.H. Horne, author of "Orion", "Cosmo de Medici" and "Death of Marlowe", etc. Leaflet showing contents of each of the three lectures. On verso, a note by Horne explaining that these lectures had been given at the Manchester Athenuem, the Literary and Scientific Institute, Marylebone, and at the Mechanics Institute, Liverpool. This leaflet is folded in with handwritten expositions (probably lectures): 1. The Bible, 31 pp. 2. Gems form Auriel (Henri Frederico Auriel, 1821-1881), 5 pp. 3. Some illustrations of Shakespeare's Art, 20 pp.113896
Acquisition: [1989.0151] "Papers of R H Horne
Cloning, characterization and functional expression of a new β -D-fructofuranosidase (Osfruct2) cDNA from Oryza sativa
No full textAppropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
The Mechanism of E–H (E = N, O) Bond Activation by a Germanium Corrole Complex: A Combined Experimental and Computational Study
No full text(TPFC)Ge(TEMPO)
(<b>1</b>, TPFC = tris(pentafluorophenyl)corrole,
TEMPO<sup>•</sup> = (2,2,6,6-tetramethylpiperidin-1-yl)oxyl)
shows high reactivity toward E–H (E = N, O) bond cleavage in
R<sub>1</sub>R<sub>2</sub>NH (R<sub>1</sub>R<sub>2</sub> = HH, <sup><i>n</i></sup>PrH, <sup><i>i</i></sup>Pr<sub>2</sub>, Et<sub>2</sub>, PhH) and ROH (R = H, CH<sub>3</sub>) under
visible light irradiation. Electron paramagnetic resonance (EPR) analyses
together with the density functional theory (DFT) calculations reveal
the E–H bond activation by [(TPFC)Ge]<sup>0</sup>(<b>2</b>)/TEMPO<sup>•</sup> radical pair, generated by photocleavage
of the labile Ge–O bond in compound <b>1</b>, involving
two sequential steps: (i) coordination of substrates to [(TPFC)Ge]<sup>0</sup> and (ii) E–H bond cleavage induced by TEMPO<sup>•</sup> through proton coupled electron transfer (PCET)
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