177,997 research outputs found
Uterine transplantation: a promising surrogate to surrogacy?
No full textUterine transplantation: a promising surrogate to surrogacy?
Grynberg M1, Ayoubi JM, Bulletti C, Frydman R, Fanchin R.
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Abstract
Infertility due to the inability of the uterus to carry a pregnancy ranks among the most unresolved issues in reproductive medicine. It affects millions of women worldwide who have congenital or acquired uterine affections, often requiring hysterectomy, and potentially represents a considerable fraction of the general infertile population. Patients suffering from severe uterine infertility are currently compelled to go through gestational surrogacy or adoption; both approaches, unfortunately, deprive them of the maternal experience of pregnancy and birth. Uterine transplantation represents an outstanding, yet complex, perspective to alleviating definitive uterine infertility. In the past decades, a number of scientific experiments conducted both in animals and women, focusing on uterine transplantation, have led to promising results. Collectively, these findings undoubtedly constitute a sound basis to clinically apply uterine transplantation in the near future. This paper is, however, an overview not only of the extent and limitations of accumulated scientific knowledge on uterine transplantation, but also its ethical implications, in an effort to define the actual place of such an approach among the therapeutic arsenal for alleviating infertility.
© 2011 New York Academy of Sciences
Frydman R. L'irrésistible désir de naissance
No full textFrydman R. L'irrésistible désir de naissance. In: Enfance, tome 39, n°1, 1986. pp. 132-133
Frydman R. L'irrésistible désir de naissance
No full textFrydman R. L'irrésistible désir de naissance. In: Enfance, tome 39, n°1, 1986. pp. 132-133
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
R. FRYDMAN, E. PAPIERNIK, C. CREMIERE et J.-L. FISCHER (éd.), Avant la naissance : 5000 ans d’images, Paris, 2009
No full textRecension par Antoine PietrobelliR. FRYDMAN, E. PAPIERNIK, C. CREMIERE et J.-L. FISCHER (éd.), Avant la naissance : 5000 ans d’images, Paris, 2009, dans la Lettre d’informations. Médecine antique et médiévale, n. s. 10, 2011, p. 14-2
R. FRYDMAN, E. PAPIERNIK, C. CREMIERE et J.-L. FISCHER (éd.), Avant la naissance : 5000 ans d’images, Paris, 2009
No full textRecension par Antoine PietrobelliR. FRYDMAN, E. PAPIERNIK, C. CREMIERE et J.-L. FISCHER (éd.), Avant la naissance : 5000 ans d’images, Paris, 2009, dans la Lettre d’informations. Médecine antique et médiévale, n. s. 10, 2011, p. 14-20International audienc
"Closing the R&D Gap, Evaluating the Sources of R&D Spending"
No full textBoth spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.
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