1,721,324 research outputs found
Evolving concept of chronic pancreatitis.
No full textChronic pancreatitis (CP) is an inflammatory disease of the pancreas characterized histologically by the presence of fibrosis and inflammation of the parenchyma with the involvement of both acini and Langherans islets.
CP has been considered in the past “one” disease, caused by alcohol, at least in the Western Countries. Epidemiological data documented an association of the disease with an excessive alcohol consumption up to the end of the last century. However, the quantification of alcohol intake was heterogeneous and a concept of risk for CP in alcohol drinkers was introduced in the absence of alcohol abuse. The clinical consequence was that the treatment of CP was mainly "symptomatic", based on alcohol withdraw and pain management in an early stage of the disease and treatment of exocrine and endocrine insufficiency in a later stage.
The integration between pathological/molecular biology and radiological findings identified distinct type of chronic pancreatitis, namely autoimmune pancreatitis, paraduodenal pancreatitis and pancreatitis associated with gene mutations.
Other forms of CP on which there is still no international agreement are represented by organic spincter of Oddi dysfunction (SOD), CP caused by scar(s) secondary to previous episodes of necrotizing pancreatitis, pancreatitis associated with anatomical abnormalities (pancreas divisum, annular pancreas) and pancreatitis associated to slow-growing tumours of the pancreas or of the periampullar region
Chapter 16: The Italian Experience
No full textThis book offers a manageable understanding of key aspects of IgG4 related disease while providing in-depth information that should well serve those seeking a deeper understanding of this unique disorder
Endoscopic ultrasonography in chronic asymptomatic pancreatic hyperenzymemia: The more we see, the less we know
No full textEditorial on endoscopic ultrasonography in chronic asymptomatic pancreatic hyperenzymemi
Acute Recurrent Pancreatitis and Dysfunction of the Sphincter of Oddi: Comparison between Invasive and Non-Invasive Technique.
No full text
- …
