1,642 research outputs found

    Preface

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    Portrait of Helen Hunt Jackson painted by A.F. Harmer in 1885, ca. 1885

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    Photograph of a portrait of Helen Hunt Jackson painted by A.F. Harmer in 1885, ca. 1885. She is turned slightly to the right and is visible from the chest up. She is wearing a high collared light-colored ruffled blouse under a dark dress. The portrait is signed with the artist's initials, "A.F.H.". Jackson was the author of the book "Ramona." Possibly painted from sittings in 1880 or 1882

    Design metrics for evaluating the propulsive efficiency of future ships

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    There is an increasing need for the ship design process to take account of environmental issues such as the emission of greenhouse gases and the likely extension of a carbon dioxide charging mechanism to international shipping. These issues, together with the need for economic viability, provide further incentives to improve the efficiency of propulsion of ships. The main components of powering are firstly reviewed. Individual components and other power saving devices are identified which should contribute to improvements in the overall efficiency of propulsion. Suitable design metrics and procedures, taking into account economic and environmental factors, are recommended for the design of future ships

    Semi-supervised assessment of incomplete LV coverage in cardiac MRI using generative adversarial nets

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    Cardiac magnetic resonance (CMR) images play a growing role in diagnostic imaging of cardiovascular diseases. Ensuring full coverage of the Left Ventricle (LV) is a basic criteria of CMR image quality. Complete LV coverage, from base to apex, precedes accurate cardiac volume and functional assessment. Incomplete coverage of the LV is identified through visual inspection, which is time-consuming and usually done retrospectively in large imaging cohorts. In this paper, we propose a novel semi-supervised method to check the coverage of LV from CMR images by using generative adversarial networks (GAN), we call it Semi-Coupled-GANs (SCGANs). To identify missing basal and apical slices in a CMR volume, a two-stage framework is proposed. First, the SCGANs generate adversarial examples and extract high-level features from the CMR images; then these image attributes are used to detect missing basal and apical slices. We constructed extensive experiments to validate the proposed method on UK Biobank with more than 6000 independent volumetric MR scans, which achieved high accuracy and robust results for missing slice detection, comparable with those of state of the art deep learning methods. The proposed method, in principle, can be adapted to other CMR image data for LV coverage assessment

    Design and implementation of the Delft molecular-dynamics processor

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    Applied SciencesApplied Science

    Un’esperienza didattica in tema di paleonutrizione

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    The item arises from an "elective" Paleopathology course suggested for students graduating in Medicine and Surgery at the University of Milan. This course discussed subjects as: molecular paleobiology, tumors and infectious paleopathology, paleonutrition, paleopathological museums and history of medicine. The author dealt with the "paleonutrition" subject. Extremely actual aspects emerged which drew the students' attention

    Screening for Cognitive Impairment by Model Assisted Cerebral Blood Flow Estimation

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    Objective: Alzheimer's disease (AD) is a progressive and debilitating neurodegenerative disease; a major health concern in the ageing population with an estimated prevalence of 46 million dementia cases worldwide. Early diagnosis is therefore crucial so mitigating treatments can be initiated at an early stage. Cerebral hypoperfusion has been linked with blood-brain barrier dysfunction in the early stages of AD, and screening for chronic cerebral hypoperfusion in individuals has been proposed for improving the early diagnosis of AD. However, ambulatory measurements of cerebral blood flow are not routinely carried out in the clinical setting. In this study, we combine physiological modelling with Holter blood pressure monitoring and carotid ultrasound imaging to predict 24-hour cerebral blood flow (CBF) profiles in individuals. One hundred and three participants (53 with mild cognitive impairment (MCI), 50 healthy controls) underwent modelassisted prediction of 24-hour CBF. Model-predicted CBF and neuropsychological tests were features in lasso regression models for MCI diagnosis. Results: A CBF-enhanced classifier for diagnosing MCI performed better, area-under-the-curve (AUC) = 0.889 (95%-CI: 0.800 to 0.978), than a classifier based only on the neuropsychological test scores, AUC = 0.818 (95%- CI: 0.643 to 0.992). An additional cohort of 25 participants (11 MCI, 14 healthy) was recruited to perform model validation by arterial spin-labelling magnetic resonance imaging and to establish a link between measured CBF and that predicted by the model. Conclusion: Ultrasound imaging and ambulatory blood pressure measurements enhanced with physiological modelling can improve MCI diagnosis accuracy

    Strategische alliantie voor Esprithuis: Strategische allianties als organisatie- en rechtsvorm van samenwerkingsverbanden in de bouw

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    Samenwerkingsverbanden binnen de bouw krijgen steeds meer aandacht. De studies naar projectallianties door de faculteit Bouwkunde van de Technische Universiteit Delft zijn daar een voorbeeld van. Door de kennis over projectallianties rijst de vraag of projectoverstijgende alliantie - zogenaamde strategische allianties - bruikbare samenwerkingsverbanden kunnen zijn voor ondernemingen in de bouw. Vereniging EspritHuis is een bedrijvenvereniging die op basis van mass customization woningen wil gaan bouwen. Mass customization vraagt van de aanbiedende partij(en) een vergaande uitwisseling van informatie over de verschillende producten die worden aangeboden. De klant krijgt in een mass customized project namelijk de vrijheid om - binnen de (ruime) grenzen van de aanbieder - zijn of haar woonwensen te realiseren. De ontwikkelingen die door Vereniging EspritHuis zijn getieerd vragen van de deelnemers aan de ontwikkeling een intensieve en langdurige samenwerking. De doelen van het ontwikkelingsproces van Vereniging EspritHuis heeft sterke parallellen met de algemene eigenschappen van een strategische alliantie. De probleemstelling van dit rapport is daarom als volgt. Gezien de eerder geschetste situatie is het waardevol de strategische alliantie als organisatie- en contractmodel te onderzoeken en te beschouwen of deze is toe te passen op procesgroep EspritHuis, die op basis van mass customization een nieuw bouwproduct op de markt wil zetten. Vanuit het huidige organisatiemodel van EspritHuis is - om alle deelnemers aan de ontwikkeling te laten wennen aan de verhoudingen binnen een strategische alliantie - een stappenplan opgesteld voor de groei naar een model wat past binnen strategische allianties. Daarnaast is op basis van de nieuwe wetgeving voor personenvennootschappen een keuzeschema opgesteld om de juiste rechtsvorm te kiezen voor de strategische alliantie. Vanuit de mededingingswetgeving is niet te verwachten dat EspritHuis beperkingen zal worden opgelegd.Architectur

    Preface

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