248 research outputs found
The Charter of Fundamental Rights as a Living Instrument: Instructions for Use
Introduction to a volume edited by the author which collects essays and studies on the Charter of Fundamental Rights of the European Union and its application
Process for the D/A conversion of signed binary codes of a bipolar time-varying signal and a digital-to-analog converter employing this process
Comparison of Infrapubic vs Penoscrotal Approaches for 3-Piece Inflatable Penile Prosthesis Placement : do We Have a Winner?
Background: The 3-piece inflatable penile prosthesis (IPP) is the gold standard treatment for male erectile dysfunction when other less invasive approaches are contra-indicated or unacceptable for the patient. There are currently 2 surgical approaches for IPP implantation: the penoscrotal (PS) and the infrapubic (IP) incision. Aim: To assess the most recent evidence on the impact of surgical approach for 3-piece IPP implantation in patients with erectile dysfunction. Methods: A systematic literature review was performed using the MEDLINE (PubMed) and Cochrane Libraries databases in November 2017 to identify all studies investigating 3-piece IPP with a specified surgical access. Outcomes: The following key words were used in combination: “infrapubic,” “transcrotal,” “penoscrotal,” “peno-scrotal,” and “penile prosthesis.” Additional references were obtained from the reference lists of full-text manuscripts. We used a narrative synthesis for the analyses of the studies. Results: 22 Studies reporting data on 3-piece IPP implantation with a specified surgical approach were found in the literature. While IPPs are most commonly positioned through a PS incision, the IP approach is a faster procedure. No cases of glans hypoesthesia after IPP placement with an IP approach were reported, and the overall peri-prosthetic infection rate was 3.3% or less. Patient satisfaction rates were higher than 80% in both groups. Conclusions: Both the IP and PS approaches are viable and effective strategies for a 3-piece IPP placement, and result in high satisfaction rates. To date there is no evidence that an incision strategy may reduce infection rates. Penile sensory loss following an IP approach remains a virtual risk. It is recommended that the surgeon executing the implant have knowledge of both accesses and be capable of tailoring the incision strategy for complex cases. The chosen method should be based on the patient's specific anatomy, surgical history, and surgeon experience. Palmisano F, Boeri L, Cristini C, et al. Comparison of Infrapubic vs Penoscrotal Approaches for 3-Piece Inflatable Penile Prosthesis Placement: Do We Have a Winner
L’evoluzione delle Città metropolitane italiane tra politica di coesione europea e PNRR
Il contributo esamina l’evoluzione delle Città metropolitane italiane focalizzandosi sul loro ruolo nella politica di coesione europea e nel Piano nazionale di ripresa e resilienza (PNRR). Durante la programmazione 2014-2020, questi enti hanno avuto un ruolo limitato nei programmi europei, ma al tempo stesso hanno cercato di partecipare attivamente. La nuova programmazione 2021-2027 e soprattutto il PNRR conferiscono alle Città metropolitane un ruolo più centrale, specialmente con i Piani urbani integrati (PUI). Tuttavia, emergono differenze significative tra le Città metropolitane nella gestione dei PUI. Il testo riflette sulle sfide durante
l’attuazione dei PUI, sottolineando la necessità di una strategia territoriale metropolitana che promuova azioni
integrate
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