262 research outputs found
Musei inclusivi. L'audiodescrizione come esperienza partecipata
No full textIl contributo illustra i risultati di un esperimento di progettazione partecipata finalizzato alla creazione di servizi museali specifici per i disabili della vista. L’analisi del comparto museale italiano e della letteratura di settore hanno messo in evidenza la necessità di avviare sul territorio processi creativi che, seguendo i principi del community engagement, consentano di restituire il patrimonio culturale ai cittadini, arginando fenomeni di esclusione sociale. Nello specifico, la collaborazione fra specialisti del settore museale e utenti finali ha portato alla realizzazione di cinque audio descrizioni pilota per il Museo Storico Archeologico dell’Università del Salento
Hemangiopericytoma/Solitary fibrous tumor of the oral cavity.
No full textHemangiopericytoma/solitary fibrous tumor is a very rare tumor of uncertain malignant potential. About 300 such cases have been reported since 1942, when Stout and Murray described these tumors as "vascular tumors arising from Zimmerman's pericytes". Under the World Health Organization (WHO) classification, hemangiopericytomas and solitary fibrous tumors of the soft tissues are regarded as features of the same entity in the soft tissue fascicle. We report the case of a 54-year-old woman who presented with a painless right-side cheek mass of 2 cm maximum diameter. The lesion was completely removed by wide surgical resection. Histologically, the tumour had staghorn-like vasculature and immunohistochemistry for Calponin, CD68 KP1, AE1-AE3, smooth muscle actin and P63, S-100 was negative; that for CD34 was positive. A diagnosis of hemangiopericytoma/solitary fibrous tumor was rendered. The patient had a normal postoperative course of healing, and 24 months later remains asymptomatic, without signs of recurrence or metastasis. Because of the rarity and unpredictable biological behavior of these tumors, long-term follow-up is necessary even after radical resection because recurrence or development of metastasis may be delayed by many years
Canine prostatic serum esterase and strain and 2D‐shear wave sonoelastography for evaluation of normal prostate in dogs: Preliminary results
No full text: Canine prostatic serum esterase (CPSE) is considered a useful tool to identify prostate disorders in dogs, with increasing interest in ultrasound (US)-based sonoelastography to non-invasively detect prostate disorders. Since no report is available about a possible correlation between these diagnostic tools, we aimed to investigate a possible correlation between strain elastography (SE) and 2D-shear wave elastography (SWE) and CPSE. Twenty-one dogs were included and, on each animal, CPSE was evaluated followed by a complete US examination and SE and 2D-SWE application. Healthy dogs were identified based on the CPSE results. All the dogs included were characterized by normal CPSE values (<52.3 ng/mL) and normal US prostate appearance. The prostate was characterized by intermediate stiffness with SE (pattern III - 84.7% for the left lobe and 79.27% for the right lobe) and softer than the abdominal wall (SR 0.6 for the left lobe and 0.56 for the right lobe), with low values for both m/s and kilopascals (kPa) for 2D-SWE, pointing that the healthy tissue is not hard. 2D-SWE results were, respectively, 13.51 ± 5.55 kPa and 2.31 ± 0.42 m/s for the left lobe and 18.05 ± 6.47 kPa and 2.39 ± 0.43 m/s for the right lobe. The significant difference between the right and left measurements expressed with kPa, not evidenced with m/s, can be considered indicative of m/s as the most reliable measurement to be considered regarding the prostate parenchyma. Even though no linear correlation was detected between CPSE and elastography values, these preliminary results evidence that the healthy prostates were characterized by a similar elastographic pattern, thus pointing that these techniques can be potentially useful to be applied in case of prostatic disorders to improve the accuracy of the final diagnosis in a non-invasive way
Decontamination of root canals with the gallium-aluminum-arsenide laser: an in vitro study.
No full textOBJECTIVES:
In this in vitro study, we investigated the bactericidal effects on root canals of 810-nm diode laser irradiation, alone or combined with sodium hypochlorite and citric acid irrigation.
MATERIALS AND METHODS:
One hundred sixteen single-rooted human teeth extracted for periodontal reasons were randomly divided into four experimental groups. The canal of each tooth was prepared with a conventional step-back technique and a pure culture of vancomycin-resistant Enterococcus faecalis grown in brain heart infusion broth was used to contaminate the root canal. The specimens were incubated at 37 degrees C for 15 d in a test tube filled with agar, adding fresh bacterial suspension every 48 h, and sent them for microbiological analysis and bacterial count. Subsequently they were divided into four groups: in group A, 29 teeth were irrigated with 2 mL of 10% citric acid solution; in group B, 29 teeth were irrigated with 2 mL 5.25% sodium hypochlorite (NaOCl) solution; in group C, 29 teeth were irradiated with 810-nm laser energy via a 200-microm optic fiber at 2.5 W power in pulsed mode (10 msec on and 10 msec off) for 5 sec; and in group D, 29 teeth were irrigated with NaOCl, irradiated with the laser, then irrigated with citric acid, and irradiated with the laser, followed again by NaOCl irrigation and laser irradiation. All the samples were again sent for microbiological analysis and bacterial count.
RESULTS:
Group A had a bactericidal effect of 0.041 log mean CFU, that of group B was 3.381 log mean CFU, and that of group C was 1.459 log mean CFU, whereas group D showed the best results, with a bactericidal effect of 7.178 log mean CFU.
CONCLUSIONS:
The use of NaOCl, citric acid, and diode laser energy together have a synergistic effect, increasing treatment efficacy and leading to significantly better decontamination of the root canal
Apicoectomies with the erbium laser: a complementary technique for retrograde endodontic treatment.
No full textOBJECTIVE: The purpose of this study was to evaluate the efficacy of erbium lasers for retrograde endodontic treatment, in terms of clinical outcome and therapeutic success.
BACKGROUND DATA: Apicoectomy with retrograde filling is a well-established surgical procedure to treat teeth affected by persistent periapical lesions. The apical root end is generally removed with burs, and the adjacent periapical tissue curetted, or alternatively treated with ultrasound or laser.
METHODS: Between 2000 and 2010, 65 apicoectomies were performed on necrotic teeth that presented apical lesions (29 men, 36 women). The lasers used in the study were the erbium:yttrium-aluminum-garnet (Er:YAG) laser, wavelength 2940 nm, and the erbium,chromium-doped:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser, wavelength 2780 nm.
RESULTS: Of the 65 teeth in the study, failure only occurred in 9 CASES, MANIFESTING AFTER DIFFERENT TIMES. THE REMAINING PATIENTS, 86.15%, experienced no complications, and their treatment followed a positive course.
CONCLUSIONS: Laser-assisted surgery increases the range of therapeutic approaches in the sphere of retrograde endodontic treatment. The results of this study show that the erbium laser, used for apicoectomy, results in a high success rate with considerable benefit in terms of clinical outcome and therapeutic success
Clinical evaluation of an oval-shaped prefabricated glass fiber post in endodontically treated premolare presenting an oval root canal cross-section: a retrospective cohort study
No full textPURPOSE:
This retrospective cohort study investigated the clinical effectiveness of preformed oval-shaped glass fiber posts in combination with a dual-curing composite resin core material in endodontically treated premolars presenting an oval root canal cross-section and restored with all-ceramic crowns over up to 45 months.
MATERIALS AND METHODS:
The study population comprised 134 patients and 154 endodontically treated premolars, with varying degrees of hard tissue loss, restored by means of oval-shaped fiber-reinforced posts. Inclusion criteria were premolars presenting an oval-shaped root canal, symptom-free endodontic therapy, root canal treatment with a minimum apical seal of 4 mm, application of rubber dam, and the need for a post and core complex because of coronal tooth loss. Four groups were defined based on the number of preserved coronal walls after endodontic treatment and before core buildup. Survival rate of the post and core restorations was determined using Kaplan-Meier analysis, and statistical analysis was performed using the log-rank test (P < .05).
RESULTS:
The posts and cores were examined clinically and radiographically. The mean observation period was 42.3 ± 2.7 months. The overall survival rate was 95.45%. Comparisons revealed that the difference between premolars with no coronal wall retention and premolars that had maintained one to four coronal walls was statistically significant (P = .0006). On the contrary, comparison between premolars with one and two residual walls was found to be not significant for the overall survival rate (P = .0698).
CONCLUSION:
A satisfactory clinical performance was observed for preformed oval-shaped glass fiber posts. Survival was higher for teeth retaining three and four coronal walls
MRI in the evaluation of facial dermal fillers in normal and complicated cases
No full textOBJECTIVES: To ascertain by MRI the presence of filler injected into facial soft tissue and characterize complications by contrast enhancement.
METHODS: Nineteen volunteers without complications were initially investigated to study the MRI features of facial fillers. We then studied another 26 patients with clinically diagnosed filler-related complications using contrast-enhanced MRI. TSE-T1-weighted, TSE-T2-weighted, fat-saturated TSE-T2-weighted, and TIRM axial and coronal scans were performed in all patients, and contrast-enhanced fat-suppressed TSE-T1-weighted scans were performed in complicated patients, who were then treated with antibiotics. Patients with soft-tissue enhancement and those without enhancement but who did not respond to therapy underwent skin biopsy. Fisher's exact test was used for statistical analysis.
RESULTS: MRI identified and quantified the extent of fillers. Contrast enhancement was detected in 9/26 patients, and skin biopsy consistently showed inflammatory granulomatous reaction, whereas in 5/17 patients without contrast enhancement, biopsy showed no granulomas. Fisher's exact test showed significant correlation (p 10 mm) was found in 16 complicated patients (65 %; levels IA/IB/IIA/IIB).
CONCLUSIONS: MRI is a useful non-invasive tool for anatomical localization of facial dermal filler; IV gadolinium administration is advised in complicated cases for characterization of granulomatous reaction.
KEY POINTS: • MRI is a non-invasive tool for facial dermal filler detection and localization. • MRI-criteria to evaluate complicated/non-complicated cases after facial dermal filler injections are defined. • Contrast-enhanced MRI detects subcutaneous inflammatory granulomatous reaction due to dermal filler. • 65 % patients with filler-related complications showed lymph-node enlargement versus 31.5 % without complications. • Lymph node enlargement involved cervical levels (IA/IB/IIA/IIB) that drained treated facial areas
Inflammatory bowel diseases: clinical update of practical guidelines
No full textIdiopathic inflammatory bowel disease (IBD) includes a collection of disorders of the gastrointestinal tract of unknown aetiology, characterized by intestinal inflammation and a chronic relapsing course associated with local and systemic complications. Traditionally, IBD comprises two prototype entities, ulcerative colitis (UC) and Crohn's disease (CID) and an intermediate variant of these diseases, indeterminate colitis which shows overlapping features of the two major forms. Over the last few years, considerable progress has been made in our knowledge of the pathogenesis of IBD, which is complex and derives from genetic, environmental and immunological interactions. The aetiology remains unclear, but it is well established that the lesions and symptoms are associated with over-production of pro-inflammatory cytokines. In this paper we briefly review the pathophysiology and the new therapeutic approaches to IBD, since from these, new achievement depends the appropriate diagnostic exams to be performed and diagnostic flow charts
Andrea Paolini, Amanda Bianchi, Paolo Crisi, Maria Veronica Giordano, Massimo Vignoli, Francesco Collivignarelli, Claudia Ristori, Sara Canal, Francesca Del Signore, Andrea De Bonis, Martina Rosto, Roberto Tamburro
No full textEvaluation of the Spirotome Device for Nasal Tumors Biopsy in Eleven Dogs
Get PDFThis study evaluated the accuracy and diagnostic quality of histological samples obtained with the Spirotome device on biopsies from dogs affected by canine nasal tumors. Eleven dogs were included in this study. The mean age was 10 years. All biopsies were successfully performed within 15 minutes. All dogs showed nasal bleeding after the biopsies, which was quickly managed by applying intranasal compression with sterile cotton swabs. Bleeding stopped within 10 minutes after sampling. All biopsy samples were considered satisfactory by the pathologist, allowing a proper histological assessment
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