157 research outputs found
Informative Design. Innovazioni di processo per una progettazione integrata
No full textThe article aims to explore the main possibilities that Building Information Modeling is offering these days, in terms of methods and processes. BIM’s typical informative methodology is deeply modifying the approach to the architectural design. In fact, it influences every single phase of the building process, imposing also a profound rethinking regarding the concept of time. Furthermore, the article outlines how the application of the BIM approach on existing buildings, both civil (EBIM) and historical (HBIM), is possible. Finally, a focus is placed on the difference that an informative design can make in managing and maintaining existing buildings
Costruzioni incompiute tra manutenzione e manutenibilità
No full textUnfinished constructions represent a contemporary unresolved problem, especially in the Italian scenario. Despite the different type, original intended use and location, the reinforced concrete used as structural material denotes a common distinctive feature of these constructions.
In recent decades, this phenomenon has been the object of scandal campaigns, mostly referred to public Administrations. By contrast, various publications and exhibitions have extensively investigated the potentials of unfinished constructions, arousing the interest of academics and designers. Nevertheless, on an operational level the issue still appears unsolved. Indeed, the incomplete constructions bring up technical and methodological problems finding no confirmation at the regulatory and legislative level, to the present day.
The proposed article is part of a research line that has already explored the phenomenon of unfinished constructions from a theoretical point of view. It aims at developing the subject, precisely referring to the reinforced concrete as the main building material. In addition to the diagnosis problems and the restoration of the damaged structures, often characterized by advanced states of decay due to the condition of incompleteness, the article provides ideas and tools maintenance- oriented
Introduzione a "Quale modernità per questo paese. I documentari e le culture dello sviluppo in Italia (1948-1962)"
No full textIncompiuto, una nuova linea di partenza : progettare la differenza per un futuro sostenibile
No full textLe contemporanee costruzioni incompiute, fattispecie diffusa globalmente dell’ambiente costruito in abbandono, solo di recente sono uscite dal tabù in cui le relega l’ineludibile condizione di epifania di un fallimento. Senza entrare nel merito dei significati teoretici ad esse attribuiti (oscillanti tra i poli sovente mistificatori dell’esaltazione e della demonizzazione) e guardando alle tendenze individuabili in alcune realizzazioni degli ultimi lustri, l’articolo intende contribuire alla definizione di un approccio analitico e progettuale orientato ai multidimensionali obiettivi della sostenibilità, per rispondere in modo concreto a molteplici portatori di interesse e istanze della collettività. Il contributo mira a dimostrare che per un futuro sostenibile del mai finito serve una nuova linea di partenza, in cui il progetto si incentri sulla differenza rispetto alle premesse culturali del processo originario interrotto.Contemporary unfinished buildings, which represent a widespread sort of abandoned built environment around the globe, have only recently shaken off the taboo to which they have been relegated by their inescapable condition as symbols of failure. The theoretical connotations attributed to them often fluctuate between the mystifying poles of exaltation and demonization; without discussing these, and looking at trends that can be identified in certain works over the last decades, the article aims to contribute to defining an analytical and design-based approach. This procedure is geared towards the multidimensional goals of sustainability, and to responding in concrete fashion to the demands of stakeholders and the community. The paper aims to demonstrate that, for the sustainable future of unfinished buildings, a new point of departure is needed, in which the design project should focus on actual differences with regard to the cultural premises of the original, interrupted building process
Conception technologique pour les bâtiments inachevés - Progettazione tecnologica per edifici incompiuti
No full textIl fenomeno delle costruzioni incompiute si manifesta in tutti i continenti con diverse entità e frequenza. Alcuni esempi sono ben noti per la loro dimensione fuori dall’ordinario, ma il più delle volte si tratta di costruzioni anonime, capillarmente disseminate nei territori, che deturpano il paesaggio e abbassano sensibilmente la qualità dell’ambiente costruito.The phenomenon of unfinished buildingsoccurs inallconti-nents with varying degrees and frequency. Some examples are well known for their out-of-theordinarydimensions, butmost of the time they are anonymous constructions, widely scattered throughout the territory, which disfigure the landscape and significantly lower the quality of thebuiltenvironmentLe phénomène des bâtiments inachevéssemanifestedans tous lescontinents, avec des degrés et une fréquence variable. Certains exemples sontbienconnuspour leursdimensions horsducommun,maisdans laplupart descas, il s'agitdeconstructionsanonymes,disséminéessur leterritoire,qui défigurent le paysage et réduisent considérablement la qualité de l'environnement bâti
Immune response to vaccines in children with celiac disease
No full textCeliac disease (CD) is an immune-mediated systemic condition evoked by ingestion of gluten and related prolamines in genetically susceptible subjects. The disease is featured by a variable combination of clinical signs, specific antibodies, HLA-DQ2 and HLA-DQ8 haplotypes, and enteropathy. Vaccination is the most potent intervention for infectious disease prevention. Several factors including age, gender, ethnicity, quality and quantity of vaccine antigen, doses, and route of administration can influence immune response to vaccination, although the main cause of variation in the responsiveness among vaccine recipients is host genetic variability. The HLA system has a fundamental role in identifying the antigens introduced into the host with the vaccines and in the development of specific antibodies, and some HLA phenotypes have been associated with a less effective immunological response. The available literature indicates that the immunological response to vaccines in CD children does not differ markedly from that of general population and antibody titres are high enough to provide long-term protection, except for hepatitis B virus vaccine. In this article, we review and discuss the scarce literature in this field in order to provide clinical practice guidelines to achieve the most efficient monitoring of the response to vaccines in pediatric CD patients
Mediterranean diet and nonalcoholic fatty liver disease
No full textNonalcoholic fatty liver disease (NAFLD) is emerging as the most common chronic liver disease, and is characterized by a wide spectrum of fat-liver disorders that can result in severe liver disease and cirrhosis. Inflammation and oxidative stress are the major risk factors involved in the pathogenesis of NAFLD. Currently, there is no consensus concerning the pharmacological treatment of NAFLD. However, lifestyle interventions based on exercise and a balanced diet for quality and quantity, are considered the cornerstone of NAFLD management. Mediterranean diet (MD), rich in polyunsaturated fats, polyphenols, vitamins and carotenoids, with their anti-inflammatory and antioxidant effects, has been suggested to be effective in preventing cardiovascular risk factors. In adults, MD has also been demonstrated to be efficacious in reducing the risk of metabolic syndrome. However, few studies are available on the effects of the MD in both adult and pediatric subjects with NAFLD. Thus, the aims of the present narrative review are to analyze the current clinical evidence on the impact of MD in patients with NAFLD, and to summarize the main mechanisms of action of MD components on this condition
Cardiometabolic risk factors in children with celiac disease on a gluten-free diet
No full textCeliac disease (CD) is an immune-mediated systemic condition evoked by gluten and related prolamines in genetically predisposed subjects. It is characterised by a variable combination of gluten-dependent clinical symptoms, CD-specific antibodies, HLA-DQ2 and HLA-DQ8 haplotypes, and enteropathy. The only therapy of CD consists of a life-long gluten free diet (GFD). Strict GFD adherence results in full clinical, serological and histological remission, avoiding long-term complications in CD patients. However, this diet is not without problems. Gluten free products have high levels of lipids, sugar and salt to improve food palatability and consistency, and subjects with CD show an excessive consumption of hypercaloric and hyperlipidic foods to compensate dietetic restriction. GFD may therefore have a negative impact on cardiometabolic risk factors such as obesity, serum lipid levels, insulin resistance, metabolic syndrome, and atherosclerosis. In adults, some studies have suggested that GFD have a beneficial effect on cardiovascular profile, whereas others have shown an atherogenic effect of GFD. In children, very few studies are available on the issue. Thus, the aim of the present narrative review was to analyze the current clinical evidence on the impact of GFD on cardiometabolic risk factors in children with CD
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