1,720,984 research outputs found
Risultati preliminari di un intervento di prevenzione delle patologie cardiovascolari e promozione della salute in un gruppo di lavoratori del settore siderurgico
No full text
Rischio cancerogeno degli idrocarburi policiclici aromatici: classificazioni e interpretazioni del monitoraggio
No full textThe polycyclic aromatic hydrocarbons (PAHs) are widespread contaminants characterized by various chemical, physical and toxic properties. The characterization of occupational and environmental exposures and the use of suitable measurements protocols are very significant because their presence in mixtures and environmental persistency. In the past few years, the knowledge concerning carcinogenicity of PAHs have been reviewed, the mechanisms involved are the interaction of PAH's metabolites with DNA and oxidative damages. The main requirement for research concerns lack of knowledge on reference values and occupational exposure's assessment in particular PAHs sampling methods that can lead to combined measurements of vapor and aerosol mixtures. Aims of this study are to describe a possible occupational sources of PAHs providing also an update of mechanism involved in their carcinogenicity and risk calculation as is done in the TEF approach. The classifications provided by International Agencies and Institutions and the limit values adopted have been reviewed and taken into account
Application of a metal free high performance liquid chromatography with inductively coupled plasma mass spectrometry (HPLC-ICP-MS) for the determination of chromium species in drinking and tap water
No full textIn some environmental and occupational setting, determination of total chromium is inadequate fora complete toxicological evaluation and risk assessment because the toxicity and bioavailability ofchromium depend upon the form or species.In this study, trivalent and hexavalent chromium compounds were determined by high performanceliquid chromatography with inductively coupled plasma mass spectrometry (HPLC–ICP-MS) equippedwith dynamic reaction cells (DRCs) and a reversed-phase C8 column. All the instruments and deviceswere metal free, thus avoiding any interference caused by leaching from metallic components.The mobile phase (EDTA2(Na) 5 mM pH 7, 40◦C) directly forms a complex with the Cr(III) in the pre-heated, allowing a single chromatographic method to be used to separate the Cr(III) EDTA complex andthe Cr(VI).This analytical method was applied in several samples of mineral and tap water with the aim todetermine a different ratio of Cr(III) and Cr(VI).In tap waters Cr(VI), ranged from 10.88 to 0.1 _g/L while Cr(III) ranged from 0.33 to 0.1 _g/L.The highest levels of Cr(VI) were measured in Brescia, a highly industrialized province in northern Italyin which high levels of Cr(VI) have been a public health concern.In commercial mineral waters, the range of Cr(III) and Cr(VI) were 0.11–0.80 _g/L and 0.25–3.4 _g/L,respectively. The method applied in this study is a rapid, sensitive (LOD 0.1 _g/L) and specific technique for determination of chromium species in water
Valutazione dello status sierologico per epatite B in allievi infermieri esposti a rischio biologico presso l'Azienda Ospedaliera di Cremona
No full textValutazione e caratterizzazione delle emissioni di particolato fine ed ultrafine in un'acciaieria elettrica
No full textRuolo del Medico Competente nella prevenzione degli infortuni sul lavoro: tra etica, scienza e buone prassi
No full text[Interdisciplinary training opportunities for residents in occupational medicine: the experience of the ERC Tour 2012].
No full textThis paper describes the experience of the School of Occupational Medicine of the University of Brescia at the current edition of the New York and New Jersey Education and Research Center--Historical Perspectives Tour on Occupational Safety and Health, that involved 5 different industrial and environmental sites, appropriate for understanding the complex occupational health and safety problems. In every site, the participants have interacted with workers and professionals and discussed about the specific work processes, to better understand the risk faced by the workers, occupational pathologies that can occur, personal protective equipment used and preventive measures adopted. This experience has been successful in provide interdisciplinary educations to occupational safety and health professionals in training in order to prepare them for the collaboration and cooperation required to solve the complex occupational health and safety problems they will face in their future careers
Metodi di valutazione del rischio da sovraccarico biomeccanico all'apparato muscoloscheletrico a confronto: esperienza applicativa di dieci anni
No full textRisk assessment for upper extremity work related muscoloskeletal disorders by applying six methods of ergonomic: a ten years experience. The objective of this research was to verify and validate the multiple step method suggested by SIMLII guidelines and to compare results obtained by use of these methods: Washington State Standard, OCRA, HAL, RULA, OREGE and STRAIN INDEX.
METHODS:
598 workstations for a total of 1800 analysis by different methods were considered, by adopting the following multiple step procedure: prelinminary evaluation by Washington State method and OCRA checklist in all the working stations, RULA or HAL as first level evaluation, OREGE or SI as second level evaluation.
RESULTS:
The preliminary evaluation resulted negative (risk absent) in the 75% of examined work stations and by using checklist OCRA optimal-acceptable condition was found in 58% by HAL in 92% of analysis, by RULA in 100%, by OREGE in 64%; by SI in 70% of examined working positions. We observed similar evaluation of strain among methods and main differences have been observed in posture and frequency assessment.
DISCUSSION AND CONCLUSION:
The preliminary evaluation by State of Washington method appears to be an adequate instrument for identify the working condition at risk. All the adopted methods were in a good agreement in two estreme situations: high risk or absent risk, expecially in absent risk conditions. Level of accordance varied on the basis of their rationale and of the role of their different components so SIML indications about the critical use of biouzechanical methods and about the possible use of more than one of them (considering working chlaracteristics) have been confirmed
Trace elements and diabetes: assessment of levels in tears and serum
No full textTear film is critical for the well-being and homeostasis of the ocular surface. Although the composition of the tear film is well known, the composition of metallic elements have yet to be analysed. Despite trace elements metabolism has been reported to play a role in the pathogenesis of diabetes mellitus, a metabolic disease that affects several aspects of homeostasis, little is known in the literature regarding concentration and possible variation of metallic elements in tear film. We studied the concentrations of several essential and non-essential metallic elements in the tear fluid and serum of patients with type II diabetes mellitus and a group of non-diabetic controls. Serum and tear fluid were collected from 97 patients: 47 type II diabetic patients and 50 non-diabetic controls. Regarding tear film, there were statistically significant differences in Zinc, Chrome, Cobalt, Manganese, Barium, and Lead between groups; the values of all metallic elements were found to be statistically significant higher in patients with mellitus type II diabetes. Regarding serum values there was a statistically significant difference in Chrome, Cobalt, and Selenium values; the concentrations of Chrome and Cobalt were higher in the control group, while Selenium concentration was higher in diabetic patients. In patients with type II diabetes, metal elements with higher concentrations in tears compared to serum were: Lead, Barium, Manganese, Cobalt, and Chrome. In the control group, the metal elements with the highest concentration in tear film compared to serum were Chrome, Manganese, Barium, and Lead. In this study, we attempted to evaluate the possible effect of a disease, such as diabetes, on the metabolism of metallic elements. Although our evidence was very interesting, it is probably limited in its accuracy due to the fact that individuals in the control group harboured ocular pathologies. This work lays the foundation for future studies
- …
