2,120 research outputs found
Death and the Inexorably Dying: A Seminar
No full textThe panel for this seminar on Death and the Inexorably Dying includes DR. HANS K. VON BRAUCHITSCH, chairman of the Department of Psychiatry of Henry Ford Hospital; DR. ROBERT M. O\u27BRYAN, associate physician in the Division of Oncology, Department of Medicine of Henry Ford Hospital; FATHER ROBERT F. WOLLARD, Episcopal Chaplain of Henry Ford Hospital; and PROFESSOR RONALD R. KOENIG, assistant professor in social work, and associate director of the Center for the Study of Dying, Death and Lethal Behavior, Department of Psychology, Wayne State University
The dramaturgy of the tragedies of John Webster and John Ford with special reference to their use of stage imagery.
No full textPhDThe imagery of the plays of John Webster and John
Ford is not only verbal: in staging as well as language
these dramas display strongly imagistic, symbolic elements.
The purpose of this thesis is to examine the seven extant
tragedies of Webster and Ford from the point of view of
their total dramatic nature - to examine the staging,
costumes, hand and large properties, movement and gestures
as well as the verbal imagery, and the interplay of these
verbal and visual elements. The original appearance, of
these plays in their contemporary theatre, and the
dramatist's intentions for performance, can only be surmised.
The original stage directions are examined for
hints of the original presentation: these stage directions
may not always be authorial, but, especially in the case of
Ford, they seem to reveal the playwright's hand. The dialogue,
too, frequently implies particular gestures,
grouping or stage placement.
The visual imagery, it is here suggested, is created
by the dramatist for several purposes: a moral or ironical
point may be silently established; a chain of related
visual motifs may bind various actions and characters into
an organic union; a visualization may appeal outward to
other works of art or theatrical or non-dramatic conventions,
enlarging the immediate significance by this shorthand
reference; visual ceremonies may make concrete the more
ephemeral words and feelings of the characters.
Each of the tragedies is studied in a separate chapter,
in the following order: Webster's The White Devil, The
Duchess of Malfi, and Appius and Virginia (the authorship
of which is disputed); John Ford's The Broken Heart,
Love's Sacrifice, 'Tis Pity She's a Whore, and Perkin
Warbeck. A conclusion indicates the differences between
Webster's more overtly theatrical visualizations and Ford's
quiet tableaux.
The thesis is accompanied by illustrations which are
either explanatory or comparative
The relationship between Ford, Kipling, Conan Doyle, Wells and British propaganda of the First World War
No full textPhDThis thesis resituates the war-writing of Ford Madox Ford, Rudyard Kipling, Arthur
Conan Doyle and H.G. Wells in relation to official British propaganda
produced during the First World War. Examining these authors' institutional
connections with propaganda that was authorised by the British government locates
some of their texts within a network of materials that were deployed to justify
Britain's involvenlent in the war. The British government, via the War Propaganda
Bureau, approached major literary figures to assist in its plan to compete
vigorously with Germany to win American support. Positioning Ford's condemnation
of Prussian culture within this institutional context reveals that his officially
commissioned books functioned as a part of the larger yet-covert government
project to influence American intellectual opinion. Although wary that Kipling's
chauvinism might offend some readers, the British government reprinted and
distributed his denunciations of the 'Hun'. Kipling was given access to censored
letters from Indian soldiers in order to assist him in depicting the Imperial forces as
united. The result, The Eyes of Asia (1918), was a set of fictional texts by Indian
soldiers celebrating French and English civilisation in contrast to German barbarism.
In addition to official propaganda, these authors produced pro-war stories, poems, and
articles independent of direct government commission. Conan Doyle's formal call for
men to volunteer to defend their country, and his public denunciations of German
atrocities, were followed by his recruitment of Sherlock Holmes to repel a possible
German invasion ("His Last Bow" (1917)). Adding to his support for the war in his
journalism and war-time fiction, Wells was appointed the Head of Enemy Propaganda
for the newly formed Ministry of Information. He resigned almost immediately
following disagreements over government strategy. This project situates historically
and examines critically these authors' differing roles in relation to British propaganda
efforts during the First World War
Redemption in the work of Francis Stuart
No full textThe idea of redemption is central to an understanding of the work
of Francis Stuart. Through an examination of its development and
expression, it is possible to demonstrate the integrity of his work and
its distinctive qualities. Such a demonstration is necessary because
Stuart's writing has been subjected to comparatively little scholarly
inquiry, although reviews of his work, especially that produced since
1949, suggest that it is impressive and important.
First, a general background to Stuart's work, a discussion of the
special problems associated with reading it, and a summary of his corpus
is provided. This indicates that the idea of redemption is important to
his earliest writing. The state of redemption is shown to be a
necessary apotheosis for Stuart's outcast heroes; it involves spiritual
suffering through which may be found a sense of reintegration and a
higher reality. This is expressed through interrelated themes such as
those of gambler, artist and ordinary man; mystic and criminal; sacred
and profane love; and spirituality and the mundane. The nature of the
redemptive experience is further elaborated by distinctive, complex
motifs, especially the hare, the ark and the woman-Christ. Their
recurrence provides an important element in the unity of Stuart's work.
Because Stuart's idea of the outcast raises important biographical
questions, an examination of the relationship between Stuart's life and
his work is made. Finally, the way in which the idea of redemption
exists in the language structures of Stuart's novels is examined, with
especial reference to his most recent work, The High Consistory. The
thesis shows that the development of the these of redemption
demonstrates the integrity of Stuart's work
John Stuart Mill’s projected science of society: 1827-1848
No full textThe purpose of the thesis is to examine John Stuart Mill’s political thought from
about 1827 to 1848 as an exercise in intellectual history. It focuses, first, on Mill’s view,
formulated by the late 1830s, that contemporary society was ‘civilized’, and second, on
his project of a science of society, which he aspired to develop in the late 1830s and
early 1840s.
By the late 1830s, Mill came to the view that his contemporary society was a
‘commercial society or civilization’, dominated by the middle, commercial class. The
first part of my thesis, constituted by Chapters 2-4, discusses the way in which Mill
formed his notion of civilization, and what he meant by the term ‘civilization’. Mill paid
attention to the implications of the rise of the middle class, and regarded such
phenomena of contemporary society as the corruption of the commercial spirit and
excessive social conformity as an inevitable consequence of the rise of the middle class.
The second part of the thesis, constituted by Chapters 5-9, examines Mill’s
projected science of society. In the late 1830s and early 1840s, Mill attempted to
develop a new science of society whose subject-matter was the nature and prospects of
commercial, civilized society. This aspiration culminated in A System of Logic,
published in 1843. In examining Mill’s projected science, I pay particular attention to
the fact that he conceived new sciences of history and of the formation of character,
both of which were indispensable in his project, although he failed to give a complete
account of these sciences. My thesis shows that the implications of his interest both in
history and in the formation of character are more significant than Mill scholars have
assumed
DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire
No full textThe majority of known human tumor-associated antigens derive from non-mutated self proteins. T cell tolerance, essential to prevent autoimmunity, must therefore be cautiously circumvented to generate cytotoxic T cell responses against these targets. Our strategy uses DNA fusion vaccines to activate high levels of peptide-specific CTL. Key foreign sequences from tetanus toxin activate tolerance-breaking CD4+ T cell help. Candidate MHC class Ibinding tumor peptide sequences are fused to the C terminus for optimal processing and presentation. To model performance against a leukemia-associated antigen in a tolerized setting, we constructed a fusion vaccine encoding an immunodominant CTL epitopederived from Friend murine leukemia virus gag protein (FMuLVgag) and vaccinated tolerant FMuLVgag-transgenic (gag-Tg) mice. Vaccination with the construct induced epitopespecificIFN-c-producing CD8+ T cells in normal and gag-Tg mice. The frequency and avidity of activated cells were reduced in gag-Tg mice, and no autoimmune injury resulted. However, these CD8+ T cells did exhibit gag-specific cytotoxicity in vitro and in vivo. Also, epitope-specific CTL killed FBL-3 leukemia cells expressing endogenous FMuLVgag antigen and protected against leukemia challenge in vivo. These results demonstrate a simple strategy to engage anti-microbial T cell help to activate epitope-specific polyclonal CD8+ T cell responses from a residual tolerized repertoire
Crimes against Humanity at the Extraordinary Chambers in the Courts of Cambodia: Is a Connection with Armed Conflict Required?
No full textβ-diversity of deep-sea holothurians and asteroids along a bathymetric gradient (NE Atlantic)
No full textMeasuring and understanding patterns of ?-diversity remain major challenges in community ecology. Recently, ?-diversity has been shown to consist of 2 distinct components: (1) spatial turnover and (2) species loss leading to nestedness. Both components structure deep-sea macrofaunal assemblages but vary in importance among taxa and ocean basins and with energy availability. Here, we present the first evidence for turnover and nestedness along a bathymetric gradient in 2 major megafaunal taxa, holothurians and asteroids. Turnover is the dominant component of ?-diversity throughout bathyal and abyssal zones in both taxa, despite major differences in ?-diversity and trophic composition. High spatial turnover suggests a role for evolutionary adaptation to environmental circumstances within depth bands. This pattern differs fundamentally from those in some macrofaunal groups in low-energy environments where abyssal nestedness is high and diversity low, with diversity maintained partly by source-sink dynamics
How Leadership in International Criminal Law is Shifting from the United States to Europe and Asia: An Analysis of Spending on and Contributions to International Criminal Courts
No full textA Rare Case of Recurrent Pylephlebitis Secondary to Diverticulitis
No full textIntroduction: Pylephlebitis is the thrombosis of the portal vein usually following an intra-abdominal infection. We present a patient with a history of diverticulitis who presented with acute pylephlebitis. Case Description/Methods: A 77-year-old woman with a history of Parkinson’s disease and polymyalgia rheumatica presented to the emergency department (ED) with acute-onset abdominal pain, nausea, and hematochezia with leukocytosis (WBC, 12.5 K/uL). Computed tomography scan (CT) showed diverticulitis of the distal descending colon and sigmoid colon, with extensive diverticulosis. She was discharged on oral ciprofloxacin and metronidazole. She returned to the ED 2.5 years later with dizziness, fever/chills, and nausea. Labs revealed WBC of 20.5 K/uL. CT showed portal vein thrombosis (PVT) supplying the right hepatic lobe segments 6 and 7. Blood cultures were negative and she was discharged, but one week later, she returned to the ED with continued fever/chills, negative blood cultures, and WBC was now 29.9 K/uL. Magnetic resonance imaging (MRI) revealed a bland portal vein thrombus vs pylephlebitis within the right portal vein extending into anterior and posterior branches, with associated perfusional alterations. Treatment consisted of 3 months of apixaban therapy and 4 weeks of parenteral ertapenem. A CT scan 1 month after her most recent ED visit showed persistent occlusive thrombus throughout the posterior right portal vein and distal right anterior portal vein. Patient was transitioned to a 1-week oral amoxicillin/clavulanate antibiotic therapy and continued her lifetime apixaban therapy. The patient’s symptoms of fever/chills, abdominal pain, and nausea were resolved 2 weeks after initial PVT diagnosis, with leukocytosis resolving 1 month after initial diagnosis (WBC 8.4 K/uL). CT 4 months after PVT onset showed no liver abnormalities, and CT 6 months after onset indicated portal veins were patent. Discussion: Pylephlebitis may present with abdominal pain and fever, and is diagnosed with CT, MRI, or ultrasound imaging. It is more likely to occur secondary to liver disease, hypercoagulative disorders, or recurrent abdominal infection as with this case. In the absence of underlying liver disease or more recent infections, we speculate that the patient’s initial diverticulitis/diverticulosis precipitated her subsequent pylephlebitis. Anticoagulation therapy is normally recommended, occasionally with surgery depending upon the severity of the thrombosis
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