49 research outputs found
Earthquakes from 1820 to 1936 in Grahamstown and surroundings (Eastern Cape Province, South Africa)
No full textThe seismicity of Grahamstown, in the Eastern Cape Province of South Africa, for the years between 1820 and 1936 is investigated with recourse to contemporaneous documentary sources, leading to the development of a seismic history incorporating consideration of the broader geo-political context. Individual studies of five regional events that were felt in Grahamstown during that period, and of one that was not, are presented. Each study includes the development of a full set of intensity data points (IDPs), which are used to determine reappraised epicentral locations and magnitudes, some of which differ significantly from previously listed parameters. The results thus obtained highlight the value of seeking out additional contemporary sources from different language groups when revisiting the source parameters of earthquakes for which no or only very limited instrumental information is available.Published45-783T. Pericolosità sismica e contributo alla definizione del rischioJCR Journalreserve
Reply to "Comment on 'Review: Strong Ground Motions--Have We Seen the Worst?' by Fleur O. Strasser and Julian J. Bommer" by Heriberta Castanos and Cinna Lomnitz
No full text
Style-of-faulting in ground-motion prediction equations
No full textEquations for the prediction of response spectral ordinates invariably include magnitude, distance and site classification as independent variables. A few equations also include style-offaulting as a fourth variable, although this has an almost negligible effect on the standard deviation of the equation. Nonetheless, style-of-faulting is a useful parameter to include in ground-motion prediction equations since the rupture mechanism of future earthquakes in a particular seismic source zone can usually be defined with some confidence. Current equations including style-of-faulting use different schemes to classify fault ruptures into various categories, which leads to uncertainty and ambiguity regarding the nature and extent of the effect of focal mechanism on ground motions. European equations for spectral ordinates do not currently include style-of-faulting factors, and seismic hazard assessments in Europe often combine, in logic-tree formulations, these equations with those from western North America that do include style-of-faulting coefficients. In this article, a simple scheme is provided to allow style-of-faulting adjustments to be made for those equations that do not include coefficients for rupture mechanism, so that style-of-faulting can be fully incorporated into the hazard calculations. This also considers the case of normal fault ruptures, not modelled in any of the current Californian equations, but which are the dominant mechanism in many parts of Europe. The scheme is validated by performing new regressions on a widely used European attenuation relationship with additional terms for style-of-faulting
An evaluation of the applicability of the NGA models to ground-motion prediction in the Euro-Mediterranean region
No full textThe first phase of the Next Generation Attenuation (NGA) project has now finished, resulting in the publication of five new sets of empirical ground-motion models for PGA, PGV and response spectral ordinates. These models mark a significant advancement in the state-of-the-art in empirical ground-motion modelling and include many effects that are not accounted for in existing European equations. Under the assumption that the Euro-Mediterranean database from which the European relationships are derived is unlikely to drastically change in the near future, a prudent question to ask is: can the NGA models be applied in Europe? In order to answer this question, the NGA model of Boore and Atkinson (PEER Report 2007/01, Pacific Earthquake Engineering Research Center, Berkeley, CA, 234 pp., 2007), which is shown to be representative of the NGA models as a suite, is compared with the dataset used for the development of the most recent European empirical ground-motion models for response spectral ordinates and peak ground velocity. The comparisons are made using analyses of model residuals and the likelihood approach of Scherbaum et al. (Bull Seism Soc Am 94(6):2164–2185, 2004). The analyses indicate that for most engineering applications, and particularly for displacement-based approaches to seismic design, the NGA models may confidently be applied within Europe. Furthermore, it is recommended that they be used in conjunction with existing European models to provide constraint on finite-fault effects and non-linear site response within logic-tree frameworks. The findings also point to the potential benefits of merging the NGA and European datasets
Comment on "Review: Strong Ground Motions--Have We Seen the Worst?" by Fleur O. Strasser and Julian J. Bommer
No full textRevisiting the relativistic ejection event in XTE J1550-564 during the 1998 outburst
No full textWe revisit the discovery outburst of the X-ray transient XTE J1550−564 during which relativistic jets were observed in 1998 September, and review the radio images obtained with the Australian Long Baseline Array, and light curves obtained with the Molonglo Observatory Synthesis Telescope and the Australia Telescope Compact Array. Based on Hi spectra, we constrain the source distance to between 3.3 and 4.9 kpc. The radio images, taken some 2 d apart, show the evolution of an ejection event. The apparent separation velocity of the two outermost ejecta is at least 1.3c and may be as large as 1.9c; when relativistic effects are taken into account, the inferred true velocity is ≥ 0.8c. The flux densities appear to peak simultaneously during the outburst, with a rather flat (although still optically thin) spectral index of −0.2
Trim17, novel E3 ubiquitin-ligase, initiates neuronal apoptosis
No full textAccumulating data indicate that the ubiquitin-proteasome system controls apoptosis by regulating the level and the function of key regulatory proteins. In this study, we identified Trim17, a member of the TRIM/RBCC protein family, as one of the critical E3 ubiquitin ligases involved in the control of neuronal apoptosis upstream of mitochondria. We show that expression of Trim17 is increased both at the mRNA and protein level in several in vitro models of transcription-dependent neuronal apoptosis. Expression of Trim17 is controlled by the PI3K/Akt/GSK3 pathway in cerebellar granule neurons (CGN). Moreover, the Trim17 protein is expressed in vivo, in apoptotic neurons that naturally die during post-natal cerebellar development. Overexpression of active Trim17 in primary CGN was sufficient to induce the intrinsic pathway of apoptosis in survival conditions. This pro-apoptotic effect was abolished in Bax(-/-) neurons and depended on the E3 activity of Trim17 conferred by its RING domain. Furthermore, knock-down of endogenous Trim17 and overexpression of dominant-negative mutants of Trim17 blocked trophic factor withdrawal-induced apoptosis both in CGN and in sympathetic neurons. Collectively, our data are the first to assign a cellular function to Trim17 by showing that its E3 activity is both necessary and sufficient for the initiation of neuronal apoptosis. Cell Death and Differentiation (2010) 17, 1928-1941; doi: 10.1038/cdd.2010.73; published online 18 June 201
