79 research outputs found

    Finite Element Modelling of a Deep Excavation in Boston Blue Clay

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    AbstractThe work investigates the behaviour of a deep excavation that forms part of a wide basement located in Boston, Massachusetts, USA. The glacial marine clay deposit is modelled with a kinematic hardening model for structured soils, its reduced bubble model version and the well-known Modified Cam Clay model. The aim of the work is to assess the effects of the added features of the advanced model, such as small-strain stiffness, structure degradation and anisotropy, on the numerical prediction of the overall behaviour of the excavation. The first part of the paper provides a brief description of the site conditions, ground profile and construction sequences for the case study under consideration. Then, the soil model calibration process using experimental undrained triaxial, self-boring pressuremeter and constant rate of strain consolidation tests is discussed. Finally, the comparison of the predicted wall deflection and ground settlements profiles with observed movements is presented

    The H3 Haplotype of the EPCR Gene Determines High sEPCR Levels in Critically-ill Septic Patients

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    Article full text The full text of this article can be found here. https://link.springer.com/article/10.1007/s40121-018-0193-2 Provide enhanced content for this article If you are an author of this publication and would like to provide additional enhanced content for your article then please contact [email protected]. The journal offers a range of additional features designed to increase visibility and readership. All features will be thoroughly peer reviewed to ensure the content is of the highest scientific standard and all features are marked as ‘peer reviewed’ to ensure readers are aware that the content has been reviewed to the same level as the articles they are being presented alongside. Moreover, all sponsorship and disclosure information is included to provide complete transparency and adherence to good publication practices. This ensures that however the content is reached the reader has a full understanding of its origin. No fees are charged for hosting additional open access content. Other enhanced features include, but are not limited to: • Slide decks • Videos and animations • Audio abstracts • Audio slides</p
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