1,488 research outputs found

    Andrew Moreton — Daniel Defoe’s Last Pseudonym

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    В данной работе рассматривается один из псевдонимов Даниэля Дефо — Эндрю Моретон. Автор приводится позиции западных исследователей Даниэля Дефо об образе Эндрю Моретона. Описаны проблемы, поднимаемые в работах Эндрю Моретона. Автор делает вывод касательно цели создания данного псевдонима.This article examines one of Daniel Defoe’s pseudonyms — Andrew Moreton. The author cites the positions of Western researcher of Daniel Defoe on the image of Andrew Moreton. The problems raised in the works of Andrew Moreton are described. The author draws a conclusion as to the purpose of the pseudonym

    Loss Compensation in Time-Dependent Elastic Metamaterials

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    Materials with properties that are modulated in time are known to display wave phenomena showing energy increasing with time, with the rate mediated by the modulation. Until now there has been no accounting for material dissipation, which clearly counteracts energy growth. This paper provides an exact expression for the amplitude of elastic or acoustic waves propagating in lossy materials with properties that are periodically modulated in time. It is found that these materials can support a special propagation regime in which waves travel at constant amplitude, with temporal modulation compensating for the normal energy dissipation. We derive a general condition under which amplification due to time-dependent properties offsets the material dissipation. This identity relates band-gap properties associated with the temporal modulation and the average of the viscosity coefficient, thereby providing a simple recipe for the design of loss-compensated mechanical metamaterials.Have a nice day :)Peer reviewe

    Botulinum neurotoxin for head and neck disorders/ [edited by] Andrew Blitzer, Brian E. Benson, Diana N. Kirke

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    Includes bibliographical references and index"Senior author Dr. Andrew Blitzer is an internationally renowned pioneer on the use of botulinum neurotoxin for functional disorders, with unparalleled expertise on this topic. Joined by co-editors Brian Benson and Diana Kirke, with multidisciplinary contributors, Botulinum Neurotoxin for Head and Neck Disorders Second Edition fills a gap in the medical literature. The unique textbook focuses on the use of botulinum neurotoxins for functional disorders of the head and neck, though with some aesthetic indications. The second edition reflects the latest advances and understanding of existing and emerging applications for botulinum neurotoxins, including new treatment paradigms, revised pharmacology, and an updated review of the literature in all chapters. Twenty superbly illustrated chapters cover the management of hyperfunctional, pain, and hypersecretory syndromes of the head and neck. Hyperfunctional motor disorders are discussed in chapters focused on blepharospasm, facial dystonia, Meige syndrome, oromandibular dystonia, spasmodic dysphonia (laryngeal dystonia), and cervical dystonia. Specific treatment approaches for pain are addressed in chapters on migraine and chronic daily tension headaches, temporomandibular disorders, and trigeminal neuralgia. The treatment of autonomic nervous system disorders is covered in chapters dedicated to Frey syndrome, facial hyperhydrosis, and sialorrhea"--Pharmacology of Botulinum Neurotoxins / Muna I. Bitar, Nikita Kohli, Maya Samman, and Andrew Blitzer -- Botulinum Neurotoxin for Blepharospasm / Amit Patel, Andrew Blitzer, and Boris L. Bentsianov -- Botulinum Neurotoxin for Facial Dystonia / Scott M. Rickert, Amy P. Wu, and Andrew Blitzer Botulinum -- Neurotoxin for Meige Syndrome / Niv Mor and Andrew Blitzer -- Botulinum Neurotoxin for Oromandibular Dystonia / Daniel Novakovic and Ajay E. Chitkara -- Botulinum Neurotoxin for Spasmodic Dysphonia / Phillip C. Song, Lucian Sulica, and Andrew Blitzer -- Botulinum Neurotoxin for Cervical Dystonia / Tanya K. Meyer, Joel Guss, and Ronda E. Alexander -- Botulinum Neurotoxin for Hemifacial Spasm and Facial Synkinesis / Lesley French Childs, Daniel Novakovic, and Scott R. Gibbs -- Botulinum Neurotoxin for Hyperfunctional Facial Lines / Brian E. Benson, Diana N. Kirke, and Andrew Blitzer -- Botulinum Neurotoxin for Upper and Lower Esophageal Spasm / Nwanmegha Young and Brian E. Benson -- Botulinum Neurotoxin for Palatal Myoclonus / Ajay E. Chitkara, Catherine F. Sinclair, and Daniel Novakovic -- Botulinum Neurotoxin for Temporomandibular Disorders, Masseteric Hypertrophy, and Cosmetic Masseter Reduction / Michael Z. Lerner and Andrew Blitzer -- Botulinum Neurotoxin Therapy in the Laryngopharynx / Craig H. Zalvan, Phillip C. Song, Nwanmegha Young, and Andrew Blitzer -- Botulinum Neurotoxin for Migraine / Rachel Kaye, Jerome Schwartz, Brian E. Benson, and William J. Binder -- Botulinum Neurotoxin for Chronic Tension Headache / Nwanmegha Young and Brian E. Benson -- Botulinum Neurotoxin for Trigeminal Neuralgia / Elizabeth Guardiani, Andrew Blitzer, Lesley French Childs, and Ronda E. Alexander -- Botulinum Neurotoxin for Frey's Syndrome / Rachel Kaye, Andrew Blitzer, and Brian E. Benson -- Botulinum Neurotoxin for Facial Hyperhidrosis / Diana N. Kirke, Daniel Novakovic, and Andrew Blitzer -- Botulinum Neurotoxin for Sialorrhea / Brianna K. Crawley, Scott M. Rickert, Senja Tomovic, and Andrew Blitzer -- Botulinum Neurotoxin for Radiation-Induced Spasm and Pain / Diana N. Kirke, Brian E. Benson, and Tanya K. Meyer1 online resourc

    A letter to Andrew Snape, [electronic resource] : occasion'd By the Strife that lately appeared among the People called, Clergy-Men. By the Author of the Declaration of Truth.

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    The author of the Declaration of truth is "almost certainly" Daniel Defoe (Furbank and Owens), and this work is sometimes attributed to him (Crossley, Trent, Hutchins, Moore, Novak). Attribution disputed by Furbank and Owens, Defoe de-attributions.Price from imprint: price 6 d.Moore,Electronic reproduction.English Short Title Catalog,Reproduction of original from British Library

    The public voices of Daniel Defoe

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    This is a study of Daniel Defoe's political rhetoric and polemical strategies between the years 1697 and 1717. It explores and analyses a representative selection of what may be termed Defoe's `public voices'. In its broadest definition, these public voices are understood to be the opinions expressed and the rhetorical stances taken by Defoe in those pieces of his writing which directly or indirectly relate to the sphere of official, governmental and national discourse and activity. In the most basic sense, this thesis attempts to highlight and explain the way in which the language, imagery and concerns of Defoe's publications were shaped by the events and attitudes of the historical moment at which they were produced. In the process, this study re-situates, and thus necessarily re-evaluates, the voices and apparent meanings of some of Defoe's better known texts, while offering extensive investigations of the rhetorical strategies of publications which have previously been neglected by Defoe scholars. In the context of the above, an attempt is made to demonstrate that the poem The True-Born Englishman (1701) was not only a response to xenophobic sentiments prevalent in English society at the turn of the century but did, in fact, represent Defoe's final, summative contribution to the standing army controversy of the late 1690s. On a similar note, this thesis aims to show that the verse satire Jure Divino (1706) was the culmination of Defoe's involvement in the occasional conformity controversy of the early 1700s and constituted on important element of his campaign in favour of religious toleration. In addition, I argue that volume one of The Family Instructor (1715) was Defoe's response to the Jacobite-inspired unrest of the years 1714-15 and, as such, represented an important political act. Finally, this study offers an extensive investigation of one of Defoe's most problematic publications, An Argument Proving that the Design of Employing and Tnobling Foreigners, Is a Treasonable Conspiracy (1717). The pamphlet, I suggest, represented a highly ironic attack on one of Defoe's old adversaries, John Toland, and only develops its full rhetorical force if read in the context of the standing army controversy

    Ethnic identity, political identity and ethnic conflict: simulating the effect of congruence between the two identities on ethnic violence and conflict

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    This thesis outlines and presents an alternative hypothetical process to the emergence of ethnic conflict. Ethnic conflicts, rather than being dependent upon pre-existing 'ancient hatreds', are instead the result of a congruence between ethnic and political identity which grants individuals the ability to use ethnicity to identify and eliminate political threats. This hypothesis is formed by the examination of three case studies of ethnic conflict: Lebanon, Northern Ireland and Croatia. This hypothesis is then formalised and tested using an agent based simulation in which agent interactions are dependent upon ethnic and political identity and the congruence between the two. As predicted there was a strong positive correlation between how accurately ethnic identity reflected political identity and the level of ethnically motivated violence in the simulation, although the relationship was not linear. Furthermore the effect of a shift in congruence was found to be roughly comparable to the effect of initialising agents with a moderate level of pre-existing ethnic antagonism

    ‘The Churchillian Paradigm and the “Other British Isles”: An Examination of Second World War Remembrance in Man, Orkney, and Jersey’

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    This dissertation studies Second World War ‘sites of memory’ in the islands of Jersey, Orkney and the Isle of Man, to determine if each island celebrates the war’s events as Britain does, or if they have charted their own mnemonic course. It builds on the work of Angus Calder, Malcolm Smith, and Mark Connelly, who have explored how popular conception of the Second World War in Britain has been structured around a certain set of commemorative motifs, most of which centre on Winston Churchill and the events of 1940. The British war narrative is now commonly referred to as the ‘Churchillian paradigm’ or ‘finest-hour myth’, and continues to be the driving force in commemoration and memorialization on the British mainland. The three islands in this study are culturally and historically distinct from Britain, and each has strong notions of its own ‘island identity’. Each also possesses a tangential and divisive domestic experience of war, one which is often minimized in the iconography of the Churchillian paradigm. Jersey was occupied by Nazi Germany from 1940 to 1945, Orkney was home to several thousand Italian POWs who built important infrastructure in the island, and the Isle of Man was home to 14,000 German, Finnish, Japanese, and Italian internees in what one critic has called ‘a bespattered page’ in the nation’s history. By examining ‘sites of memory’— museums, heritage sites, commemorations, celebrations, philately, and use of public space—this dissertation shows that each island simultaneously accepts and rejects elements of the finest-hour myth in their collective memory. Each island displays its unique (though often quite negative) heritage in order to differentiate itself from Britain, while at the same time allowing them, at certain events, to participate in celebration of Britain’s ‘greatest victory’. In this way, islands’ use ‘Britishness’ pragmatically, by basking in traditionally ‘British’ commemorative tropes, while at the same time deepening their own cultural and historical sovereignty

    Daniel Ortega Visit to Atlanta, Georgia, 1984

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    Atlanta Mayor Andrew Young presents Daniel and Rosario Murillo de Ortega with a gift during an event that was part of the Ortegas' visit to Atlanta, Georgia. For more information about the Ortegas' visit to Atlanta, see pages 34-37 in the December-January 1984-1985 SCLC Magazine issue: http://hdl.handle.net/20.500.12322/auc.199:07388.The Atlanta University Center Robert W. Woodruff Library acknowledges the generous support of the Joseph & Evelyn Lowery Institute for Justice and Human Rights, the Joseph Echols Lowery Irrevocable Trust, and other donors in supporting the processing and digitization of Morehouse College's Joseph Echols and Evelyn Gibson Lowery Collection

    Oxygen targets in the intensive care unit during mechanical ventilation for acute respiratory distress syndrome: a rapid review

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    Background: supplemental oxygen is frequently administered to patients with acute respiratory distress syndrome (ARDS), including ARDS secondary to viral illness such as coronavirus disease 19 (COVID-19). An up-to-date understanding of how best to target this therapy (e.g. arterial partial pressure of oxygen (PaO2) or peripheral oxygen saturation (SpO2) aim) in these patients is urgently required.Objectives: to address how oxygen therapy should be targeted in adults with ARDS (particularly ARDS secondary to COVID-19 or other respiratory viruses) and requiring mechanical ventilation in an intensive care unit, and the impact oxygen therapy has on mortality, days ventilated, days of catecholamine use, requirement for renal replacement therapy, and quality of life.Search methods: we searched the Cochrane COVID-19 Study Register, CENTRAL, MEDLINE, and Embase from inception to 15 May 2020 for ongoing or completed randomized controlled trials (RCTs).Selection criteria: two review authors independently assessed all records in accordance with standard Cochrane methodology for study selection. We included RCTs comparing supplemental oxygen administration (i.e. different target PaO2 or SpO2 ranges) in adults with ARDS and receiving mechanical ventilation in an intensive care setting. We excluded studies exploring oxygen administration in patients with different underlying diagnoses or those receiving non-invasive ventilation, high-flow nasal oxygen, or oxygen via facemask.Data collection and analysis: one review author performed data extraction, which a second review author checked. We assessed risk of bias in included studies using the Cochrane 'Risk of bias' tool. We used the GRADE approach to judge the certainty of the evidence for the following outcomes; mortality at longest follow-up, days ventilated, days of catecholamine use, and requirement for renal replacement therapy.Main results: we identified one completed RCT evaluating oxygen targets in patients with ARDS receiving mechanical ventilation in an intensive care setting. The study randomized 205 mechanically ventilated patients with ARDS to either conservative (PaO2 55 to 70 mmHg, or SpO2 88% to 92%) or liberal (PaO2 90 to 105 mmHg, or SpO2 ≥ 96%) oxygen therapy for seven days. Overall risk of bias was high (due to lack of blinding, small numbers of participants, and the trial stopping prematurely), and we assessed the certainty of the evidence as very low. The available data suggested that mortality at 90 days may be higher in those participants receiving a lower oxygen target (odds ratio (OR) 1.83, 95% confidence interval (CI) 1.03 to 3.27). There was no evidence of a difference between the lower and higher target groups in mean number of days ventilated (14.0, 95% CI 10.0 to 18.0 versus 14.5, 95% CI 11.8 to 17.1); number of days of catecholamine use (8.0, 95% CI 5.5 to 10.5 versus 7.2, 95% CI 5.9 to 8.4); or participants receiving renal replacement therapy (13.7%, 95% CI 5.8% to 21.6% versus 12.0%, 95% CI 5.0% to 19.1%). Quality of life was not reported.Authors' conclusion: we are very uncertain as to whether a higher or lower oxygen target is more beneficial in patients with ARDS and receiving mechanical ventilation in an intensive care setting. We identified only one RCT with a total of 205 participants exploring this question, and rated the risk of bias as high and the certainty of the findings as very low. Further well-conducted studies are urgently needed to increase the certainty of the findings reported here. This review should be updated when more evidence is available.</p
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