1,721,007 research outputs found

    Dalla riattivazione dell’Habana Vieja all’adattamento climatico del Malecón Tradicional

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    Di fondamentale importanza per la riattivazione dell’Habana Vieja è stato, fin con la stesura del PEDI 1998 e poi del PEDI 2011 Avance, il sostegno di un processo di recupero che si autofinanziasse. L'articolo descrive le principali tappe di questo importante progetto di rigenerazione e adattamento del centro storico patrimonio Unesco

    Rischi naturali e città. La validità dell'approccio riformista per un'urbanistica attenta ai rischi

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    Il contributo mette in risalto come l'approccio riformista (tipico della scuola camposiana) abbia colto da tempo la necessità di integrare nello strumento urbanistico ordinario un insieme di dispositivi capaci di traghettare le città verso una dimensione resiliente ai rischi naturali e ai cambiamenti climatici. Il contributo, in particolare, esplorerà tre vicende di pianificazione italiana

    Diritto e territorio: l’evoluzione dell’urbanistica

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    Recensione al libro di Maria Cristina Cabiddu "Il governo del terriotrio", Laterza, Roma 201

    Pavia 1976-1977. Il centro storico nel PRG del 1976

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    Il contributo restituisce l'esperienza del Piano di Pavia elaborato alla fine degli anni '70 ponendo l'accento sulle azioni messe in campo per la protezione e valorizzazione del centro storico

    Il Poru di Senigallia

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    Il contributo inquadra il tema della rigenerazione urbana e in particolare come si stia sviluppando in Italia attraverso il racconto di alcune prime riflessioni maturate durante la redazione del Programma Operativo di riqualificazione urbana (Poru) di Senigallia (An)

    COVID-19 and estimates of actual deaths in Italy. Scenarios for urban planning in Lombardy

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    This research investigates the direct effects of the Covid-19 pandemic in Italy, focusing on Lombardy, the most affected region by the pandemic both in the first wave of infection (March–April 2020) as well as in the second wave (October–November 2020). We analyzed the data of the death tolls provided by the Italian National Institute of Statistics in April 2020 with the aim to provide reliable estimates and maps of deaths due to Covid-19 at the local scale, and hence better guiding decisions on spatial planning.Firstly, we performed a statistical analysis at the national level, carried out on a region-by-region basis, to compare the total number of deaths in 2020 to the average values of the previous five years. We focused on the last three weeks of March when the lockdown restrictions have been fully applied. We observed that the mortality rate has been much higher than the average recorded in recent years (2015–2019), both in Italy and Lombardy. Additionally, we estimated that the ‘excess deaths’ in March 2020 are more than fourfold (325% in Italy) the official number of deaths due to Covid-19 reported by the Ministry of Health. This leads to the dramatic consideration that most of the Covid-19-related deaths occurred at home.Lastly, using geo-referenced data by Geographic Information System analysis at the municipality scale, we investigated the Covid-19 effects by grouping the deceased into five age-groups, aiming to map the correlation between geography and population age. Lombardy is a wide region, characterized by various territories, such as mountains, flat landscapes, metropolitan and touristic areas. The Covid-19 pandemic affected each area in a specific way. For each of them, according to the demographic pyramid's reconfiguration, we should assume an urban planning scenario that is place-based, sustainable and resilient

    Anti-beta 2-glycoprotein I antibodies in a patient with catastrophic antphospholipid syndrome.

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    IF: 0,559 Autoimmune antiphospholipid antibodies are a hallmark of patients with antiphospholipid syndrome, and require a protein cofactor, beta 2-glycoprotein I, to bind anionic phospholipids. In these same patients, moreover, IgG directly binding beta 2-glycoprotein I are described. We found high plasma titres of both IgM and IgG anti beta 2-glycoprotein I antibodies in a patient with catastrophic antiphospholipid syndrome. After passing plasma through a Sephacryl S-300 column, an identical distribution pattern between anti beta 2- glycoprotein I and anticardiolipin antibodies was observed. Moreover, when IgG immunocomplexes were isolated from a high molecular fraction, IgM anti- beta 2-glycoprotein I and anticardiolipin antibodies were detected. Thus IgG, IgM ad IgG-IgM complexes of anti-beta 2-glycoprotein I antibodies are present at the same time in a patient with antiphospholipid syndrome
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