76 research outputs found
Automatic observation of blazars: future developments.
No full textThe author discusses the possible characteristics of a robotic telescope
suitable for automatic observations of blazars and presents some of the
features of the new 80 cm telescope that is in advanced phase of
construction at the Perugia University Observatory
Treatment-Resistant Acute Upper Limb Ischemia in a Patient With Systemic Lupus Erythematous and Concomitant SARS-CoV-2 Infection. A Case Report
No full textTo describe the case of a young female patient, affected by Systemic Lupus Erythematous, hospitalized for severe SARS-CoV-2 infection pneumonia and presenting a treatment-resistant acute upper limb ischemia. Two days after hospital admission, the patient suffered sudden right upper limb pain associated with mild functional impairment. At physical examination, radial and ulnar pulses were absent, and no flow signal was detected at duplex ultrasound scan. Therefore, an acute limb ischemia diagnoses was posed. Despite several surgical and endovascular revascularization attempts, the patient underwent an above the elbow amputation in 10th postoperative day from first surgical embolectomy, and she died for respiratory failure 25 days after hospitalization. Our case of acute upper limb ischemia seems to confirm that clinical manifestation and fate of thrombotic disorder in COVID-19 patients could be precipitated by concomitant autoimmune diseases
Experimental and theoretical investigation on road pavements and materials through ground-penetrating radar
No full textGround-penetrating radar (GPR) is being increasingly used over the last years in a wide range of applications, due to its flexibility and high potential to provide characterization and imaging of structures and materials. Overall, several reasons are contributing to increase the demand for the use of this tool and non-destructive testing techniques (NDTs) in general. Amongst all, it is worth citing technological advances of both hardware and software elements, an intrinsic lower significance of measurements provided by traditional monitoring techniques along with their greater invasiveness in measuring processes and, last but not least, the impacts of Global Economic Crisis on the use of economic resources affecting for years countries worldwide. The combination of such factors has led the interest of several skill profiles spanning from researchers, practitioners and end-users in general, and focused the attention of governments and local authorities on the high capabilities to gather a large amount of information in a relatively short time of surveying.
In the field of pavement engineering, GPR has been used since the early 1980s mostly focusing on the geometrical characterization of road structure, by evaluating layer thicknesses. Minor care has been given to the analysis of the main causes of damage and performance properties of pavements, in order to improve management of infrastructural asset through effective and efficient maintenance and rehabilitation actions, as well as to provide best conditions in design of new roads.
In that regard, this thesis is aimed to give a useful contribution also in the perspective of road safety issues by improving current processes of management and maintenance of road asset, along with the design of new roads, and provide effective support for the application and practical use of the tools described. Efforts have been spent in order to detect and quantify those physical and strength characteristics of road materials and subgrade soils that are relevant causes of damage, such that an effective planning of supporting actions for maintenance, rehabilitation and design of new roads may be timely performed.
Three main topics are addressed, namely: i) the evaluation of moisture spatial field in subgrade soils through a self-consistent frequency-based technique and the analysis of radar support scale in small-scale measurements of water content; ii) the potential to detect and quantify clay content in load-bearing layers and subgrade soils through different GPR tools and signal processing techniques, and iii) the possibility to infer strength and deformation characteristics of both bound, unbound pavement structures, and subgrade soils from their electric properties.
The results are encouraging for applications in the field of pavement engineering
Acute Delta Hepatitis in Italy spanning three decades (1991–2019): Evidence for the effectiveness of the hepatitis B vaccination campaign
No full text: Updated incidence data of acute Delta virus hepatitis (HDV) are lacking worldwide. Our aim was to evaluate incidence of and risk factors for acute HDV in Italy after the introduction of the compulsory vaccination against hepatitis B virus (HBV) in 1991. Data were obtained from the National Surveillance System of acute viral hepatitis (SEIEVA). Independent predictors of HDV were assessed by logistic-regression analysis. The incidence of acute HDV per 1-million population declined from 3.2 cases in 1987 to 0.04 in 2019, parallel to that of acute HBV per 100,000 from 10.0 to 0.39 cases during the same period. The median age of cases increased from 27 years in the decade 1991-1999 to 44 years in the decade 2010-2019 (p < .001). Over the same period, the male/female ratio decreased from 3.8 to 2.1, the proportion of coinfections increased from 55% to 75% (p = .003) and that of HBsAg positive acute hepatitis tested for by IgM anti-HDV linearly decreased from 50.1% to 34.1% (p < .001). People born abroad accounted for 24.6% of cases in 2004-2010 and 32.1% in 2011-2019. In the period 2010-2019, risky sexual behaviour (O.R. 4.2; 95%CI: 1.4-12.8) was the sole independent predictor of acute HDV; conversely intravenous drug use was no longer associated (O.R. 1.25; 95%CI: 0.15-10.22) with this. In conclusion, HBV vaccination was an effective measure to control acute HDV. Intravenous drug use is no longer an efficient mode of HDV spread. Testing for IgM-anti HDV is a grey area requiring alert. Acute HDV in foreigners should be monitored in the years to come
risk factors of aminotransferase elevation in a population of virus-free blood donors. A multicentre italian study
No full textAcute Delta Hepatitis in Italy spanning three decades (1991-2019): Evidence for the effectiveness of the hepatitis B vaccination campaign
No full textUpdated incidence data of acute Delta virus hepatitis (HDV) are lacking worldwide. Our aim was to evaluate incidence of and risk factors for acute HDV in Italy after the introduction of the compulsory vaccination against hepatitis B virus (HBV) in 1991. Data were obtained from the National Surveillance System of acute viral hepatitis (SEIEVA). Independent predictors of HDV were assessed by logistic-regression analysis. The incidence of acute HDV per 1-million population declined from 3.2 cases in 1987 to 0.04 in 2019, parallel to that of acute HBV per 100,000 from 10.0 to 0.39 cases during the same period. The median age of cases increased from 27 years in the decade 1991-1999 to 44 years in the decade 2010-2019 (p < .001). Over the same period, the male/female ratio decreased from 3.8 to 2.1, the proportion of coinfections increased from 55% to 75% (p = .003) and that of HBsAg positive acute hepatitis tested for by IgM anti-HDV linearly decreased from 50.1% to 34.1% (p < .001). People born abroad accounted for 24.6% of cases in 2004-2010 and 32.1% in 2011-2019. In the period 2010-2019, risky sexual behaviour (O.R. 4.2; 95%CI: 1.4-12.8) was the sole independent predictor of acute HDV; conversely intravenous drug use was no longer associated (O.R. 1.25; 95%CI: 0.15-10.22) with this. In conclusion, HBV vaccination was an effective measure to control acute HDV. Intravenous drug use is no longer an efficient mode of HDV spread. Testing for IgM-anti HDV is a grey area requiring alert. Acute HDV in foreigners should be monitored in the years to come
Risk factors for transient and persistent aminotransferase elevation in virus-free blood donors. A multicentre study.
No full textRisk factors of aminotransferase elevation in a population of virus-free blood donors. A multicentre italian study?
No full textfattori di rischio di elevazione transitoria o persistente delle transaminasi in una popolazione di donatori di sangue. Studio italiano multicentrico.
No full textEtiology of and risk factors for transient and persistent aminotransferase elevation in a population of virus-free blood donors: a multicentre study
No full textAim: We evaluated the etiology and risk factors for transient and persistently elevated aspartate and/or alanine aminotransferase levels in virus-free blood donors. Methods: Inclusion criteria: HBsAg/HBV-DNA and anti-HCV/HCV-RNA negative blood donors with elevated aspartate aminotransferase and/or alanine aminotransferase, observed in 5 blood transfusion centres in Italy from 2004 to 2005. Aspartate aminotransferase/alanine aminotransferase levels were measured at entry and every 2 months during a period of 6 months. Results: 291 individuals were evaluated (144 with persistent and 147 with transient abnormal aminotransferases). High body mass index was the most frequent (75.5%) etiological factor and was more common in the persistent elevated levels group, compared to the transient elevated levels group (82.0% vs 65.3%; p 2 units/day) was reported in 23.6%, with no differences between the two groups. Instead, recent use of medication or paint exposure were most frequently associated with transient elevated levels than persistent elevated levels (61.6% vs 23.3% for drugs and 13.7% vs 4.3% for paint, p 29.9). Conclusions: In virus-free blood donors, excessive body mass index is the most frequent etiological factor of abnormal aminotransferases and it is the sole risk factor associated with persistently elevated aminotransferases. (C) 2009 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved
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