29 research outputs found
XENOTRANSPLANTATION OF MICROENCAPSULATED CANINE ISLETSW IN DIABETIC NOD MICE : PROLONGATION OF GRAFT SURBìVIVAL WITH SUPEROXIDE SCAVENGERS
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GLUCOCORTICOIDI E RESISTENZA INSULINICA : STUDIO DEGLI EFFETTI DI DESAMETASONE, BTAMETASONE E TRIAMCINOLONE SUI RECETTORI INSULINICI DEI MONOCITI
No full text[Hormono-metabolic profiles of patients with diabetes mellitus type 2 and acquired sulfonylurea insensitivity].
No full textLong-term treatment with thalidomide for severe recurrent hemorrhage from intestinal angiodysplasia in Glanzmann Thrombasthenia
No full textGastrointestinal angiodysplasia (GIA) is the most common cause of occult gastrointestinal bleeding (GIB) requiring often hospitalization and transfusions, especially in patients with hemorrhagic disorders. Thalidomide, impairing neo-angiogenesis, has been successfully used in the management of bleeding in patients with GIA and in particular in patients with inherited bleeding disorders. Only one case of short-term treatment with thalidomide in a patient with Glanzmann thrombasthenia (GT) and recurrent GIB due to GIA has been reported so far. We report the case of a woman with GT developing high frequency recurrent GIB due to GIA requiring repeated blood and platelet transfusions, who was treated with thalidomide obtaining a striking and stable reduction of GIB and of the requirement of platelet and blood transfusions for over 5 years. Moreover, we raise the suspicion that the association between GT and GIA may not be fortuitous
BIGUANIDI E METABOLISMO GLUCIDICO : EFFETTI DELLA METFORMINA SUI RECETTORI INSULINICI DI SOGGETTI NORMALI
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