12,922 research outputs found
“Process for the preparation of 3,6-di-O-acethyl-D-glycals via transacylation and regioselective enzymic hydrolysis”
No full textRegioselective hydrolysis in 6-O position, catalyzed by immobilied lipases . Migration of the acethyl group from 6 to 4 position, givs 3,6-di-O-acethyl-D-glycals in high yields
Procedimento per la preparazione di 3,6-di-O-acetil-D-glicali
No full textidrolisi regioselettiva di glicali per acetilat
D-piranosamine peracetilate 3-monodeprotette e procedimento per la loro preparazione
No full textIdrolisi regioselettiva di piranosamine completamente acetilate, catalizzata da lipasi immobilizzat
“One-pot” synthesis of 2-acetamido-2-deoxy-1,3,6-tri-O-acetyl-α-D-glucopyranose as intermediate for α-D-lactosamine octaacetate preparation
No full textWe have recently reported the synthesis of different acyl pyranoses, bearing only one free
hydroxyl group, obtained by regioselective enzymatic hydrolysis of the peracetylated precursors
and subsequent acyl migration of the hydrolyzed products. As a part of this ongoing research,
we have focused our attention onto the pure regioisomers of 2-acetamido-2-deoxy-1,3,4,6-tetra-
O-acetyl-α-D-glucopyranose (1) as key intermediate for the preparation of a large number of
oligosaccharides. Particularly, we have developed an efficient process to obtain a deprotected
derivative of 1 having only one free hydroxyl group at the C-4 position (3) as a valuable synthon
for the preparation of N-acetyl-α-D-lactosamine heptaacetate (4), building-block in a new
synthetic pathway for oligosaccharides like Sialyl Lewis x. Our chemo-enzymatic strategy allows
to obtain the disaccharide (4) in good overall yield, starting from a commercially available cheap
compound and without any intermediate purification. Our approach is, indeed, an interesting
alternative to the classical multi-step chemical procedures that are often plagued by low yields
and formation of undesired by-products
Sintesi one-pot di 2-acetamido-2-desossi-1,3,6-tri-O-acetil-alfa-D-glucopiranosio per la preparazione di N-acetil-D-lattosamina octaacetato
No full textOne-pot synthesis of 2-acetamido-2-deoxy-1,3,6-tri-O-acetyl-apha-D-glucopyranose as intermediate for the synthesis of N-acetyl-D-lactosamine octaacetate
No full text
MABS validation through repeated execution and data mining analysis
No full textAgent Based Modelling is the most interesting and advanced approach for simulating a complex system: in a social context, the single parts and the whole are often very hard to describe in detail. Besides, there are agent based formalisms which allow to study the emergency of social behaviour with the creation and study of models, known as artificial societies. Thanks to the ever increasing computational power, it's been possible to use such models to create software, based on intelligent agents, which aggregate behaviour is complex and difficult to predict, and can be used in open and distributed systems. Data mining is born in the last decades in order to help users in finding useful knowledge from the otherwise overwhelming amount of data available nowadays from the web and the data collected every day by companies. Data Mining techniques can therefore be the keystone to reveal non-trivial knowledge expressed by the initial assumption used to build the micro-level of the model and the structure of the society of agents that emerged from the simulation
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