374 research outputs found
Student Teaching Internship, Monsignor John R. Hackett High School
6 p.The author describes her experience as a high school student teacher.Monsignor John R. Hackett High School. Kalamazoo, Michigan
14th annual John Perkins Lecture
Dr. John Perkins returns to campus Tuesday, April 30, 11 a.m., at First Free Methodist Church, for the 14th annual John Perkins Lecture Series. This year’s morning event features Erna Kim Hackett, executive pastor at The Way Berkeley. Later that day, Hackett and Dr. Perkins will continue the morning’s topic, “Words Have Power,” at 7:30 p.m., also in First Free Methodist Church.
John Perkins is one of the leading evangelical voices to come out of the American civil rights movement and an internationally known author, speaker, and teacher. His is the co-founder of SPU’s John Perkins Center for Reconciliation, Leadership Training, and Community Development and the author of the new book One Blood: Parting Words to the Church on Race and Love. Erna Kim Hackett served with InterVarsity for 18 years in Black Ministries and Urban Programs. She is a preacher, pastor, writer, activist, and singer
2007 - biennial review - 2009
Reporting period: July 1, 2007-June 30, 2009.Assembled and reviewed by: Reagan Waskom, Nancy Grice, Zach Hittle, Kevin Hackett
Corrigendum to “Accumulation and potential for transport of microplastics in stormwater drains into marine environments, Perth region, Western Australia” [Mar. Pollut. Bull. 168 (2021) 112362]
The authors regret that the original manuscript failed to appropriately acknowledge all sources of intellectual and technical contribution, which warrant co-authorship. Dr Mark J Hackett (School of Molecular and Life Sciences, Curtin University, Bentley 6102 WA, Australia) is now recognised as a co-author of this manuscript with respect to intellectual input into the design of ATR-FTIR experiments and interpretation of the ATR-FTIR spectra. Dr Hackett is also recognised as the sole co-author responsible for training the first author of this paper in the use of ATR-FTIR research equipment. The ATR-FTIR equipment used for this study is housed within the School of Molecular and Life Sciences at Curtin University, and all authors gratefully acknowledge Curtin University for providing access to this equipment. The authors would like to apologise for any inconvenience caused. Natasha Lutz: Conceptualization, Methodology, Software, Data curation, Investigation, Formal analysis, Visualization, Writing – original draft, Writing – review & editing. James Fogarty: Data curation, Formal analysis, Methodology, Writing – review & editing, Supervision. Andrew Rate: Conceptualization, Methodology, Writing – review & editing, Supervision. Mark J. Hackett: Investigation, Data curation, Visualization
MCL-1 localizes to sites of DNA damage and regulates DNA damage response
MCL-1, a pro-survival member of the BCL-2 family, was previously shown to have functions in ATR-dependent Chk1 phosphorylation following DNA damage. To further delineate these functions, we explored possible differences in DNA damage response caused by lack of MCL-1 in mouse embryo fibroblasts (MEFs). As expected, Mcl-1(-/-) MEFs had delayed Chk1 phosphorylation following etoposide treatment, compared to wild type MEFs. However, their response to hydroxyurea, which causes a G(1)/S checkpoint response, was not significantly different. In addition, appearance of gamma-H2AX was delayed in the Mcl-1(-/-) MEFs treated with etoposide. We next investigated whether MCL-1 is present, together with other DNA damage response proteins, at the sites of DNA damage. Immunoprecipitation of etoposide-treated extracts with anti-MCL-1 antibody showed association of MCL-1 with gamma-H2AX as well as NBS1. Immunofluorescent staining for MCL-1 further showed increased co-staining of MCL-1 and NBS1 following DNA damage. By using a system that creates DNA double strand breaks at specific sites in the genome, we demonstrated that MCL-1 is recruited directly adjacent to the sites of damage. Finally, in a direct demonstration of the importance of MCL-1 in allowing proper repair of DNA damage, we found that treatment for two brief exposures to etoposide , followed by periods of recovery, which mimics the clinical situation of etoposide use, resulted in greater accumulation of chromosomal abnormalities in the MEFs that lacked MCL-1. Together, these data indicate an important role for MCL-1 in coordinating DNA damage mediated checkpoint response, and have broad implications for the importance of MCL-1 in maintenance of genome integrity.Peer reviewedfinal article publishedprotein complexchromosomesG2/McheckpointDNA repai
Facet Theory and the Mapping Sentence: Evolving Philosophy, Use and Application
How do we think about the worlds we live in? The formation of categories of events and objects seems to be a fundamental orientation procedure. Facet theory and its main tool, the mapping sentence, deal with categories of behavior and experience, their interrelationship, and their unification as our worldviews. In this book Hackett reviews philosophical writing along with neuroscientific research and information form other disciplines to provide a context for facet theory and the qualitative developments in this approach. With a variety of examples, the author proposes mapping sentences as a new way of understanding and defining complex behavior
Lymphoma survivors’ experiences at the end of treatment
Aims and Objectives To explore lymphoma survivors’ experiences on their end of treatment and follow‐up care at a large urban haematology centre in Ireland. Methods This was a qualitative study using semistructured interviews with lymphoma patients post‐treatment (n = 14). Thematic analysis guided the analysis of interview data. The study adhered to the consolidated criteria for reporting qualitative research (COREQ) guidelines. Findings Five main themes were identified following analysis of the interview data: dealing with uncertainty, changed relationships, returning to work, extended recovery time and concerns for the future. Findings of note were that some participants were unaware that their treatment had ended, many experienced recurrent infections which prolonged recovery time, and many had no recall of discussions on healthy lifestyle behaviours or recommended screening programmes at their follow‐up visits. Conclusions The findings suggest that the period of transition from active treatment to survivorship can be challenging for lymphoma survivors, and they experience ongoing needs. While the challenges of survivorship in lymphoma mirror those of other cancers, this cohort of patients require focused preparation for the end of active treatment and the transition to follow‐up care. Moreover, this patient group requires repeated specific education on late effects and second cancers, education with regards to identifying the signs of cancer recurrence and promotion of healthy lifestyle practices. Relevance to clinical practice This study highlights the importance of a dedicated end of treatment visit with the clinical nurse specialist to confirm the completion of active treatment with lymphoma patients and focus on health promotion.peer-reviewed2019-09-0
Co-authoring in Academic Research:From quarter-baked intuition to publication
Dr Ciara Hackett (QUB School of Law) and Prof Harry Van Buren (the University of Tennessee at Chattanooga and Honorary Professor, QUB School of Law) speak with Dr Ciarán O’Kelly about co-authoring in academic research.They ask how accurate and, indeed, how healthy it is to think of academics as solitary actors. They discuss both the merits of and the challenges involved in collaboration and co-authoring. Who ought one co-author with? What workflows work best? What ethical issues emerge
Lymphoma survivors\u27 experiences at the end of treatment
Aims and Objectives
To explore lymphoma survivors’ experiences on their end of treatment and follow‐up care at a large urban haematology centre in Ireland.
Methods
This was a qualitative study using semistructured interviews with lymphoma patients post‐treatment (n = 14). Thematic analysis guided the analysis of interview data. The study adhered to the consolidated criteria for reporting qualitative research (COREQ) guidelines.
Findings
Five main themes were identified following analysis of the interview data: dealing with uncertainty, changed relationships, returning to work, extended recovery time and concerns for the future. Findings of note were that some participants were unaware that their treatment had ended, many experienced recurrent infections which prolonged recovery time, and many had no recall of discussions on healthy lifestyle behaviours or recommended screening programmes at their follow‐up visits.
Conclusions
The findings suggest that the period of transition from active treatment to survivorship can be challenging for lymphoma survivors, and they experience ongoing needs. While the challenges of survivorship in lymphoma mirror those of other cancers, this cohort of patients require focused preparation for the end of active treatment and the transition to follow‐up care. Moreover, this patient group requires repeated specific education on late effects and second cancers, education with regards to identifying the signs of cancer recurrence and promotion of healthy lifestyle practices.
Relevance to clinical practice
This study highlights the importance of a dedicated end of treatment visit with the clinical nurse specialist to confirm the completion of active treatment with lymphoma patients and focus on health promotion.2019-09-0
Co-authoring in Academic Research:From quarter-baked intuition to publication
Dr Ciara Hackett (QUB School of Law) and Prof Harry Van Buren (the University of Tennessee at Chattanooga and Honorary Professor, QUB School of Law) speak with Dr Ciarán O’Kelly about co-authoring in academic research.They ask how accurate and, indeed, how healthy it is to think of academics as solitary actors. They discuss both the merits of and the challenges involved in collaboration and co-authoring. Who ought one co-author with? What workflows work best? What ethical issues emerge
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