196,172 research outputs found
Conservative management of orbital involvement in malignant tumors: Is the paradigm evolving? A critical review
No full textPurpose of reviewReview the recent literature regarding conservative management of orbital invasion in sinonasal cancers.Recent findingsRecent data seem to confirm the possibility to preserve the orbital content in a significant number of patients. MRI is the best available imaging tool for evaluating orbital invasion. Limited periorbital and extraconal fat invasion should not be considered an indication for orbital cleaning. Histology-driven neoadjuvant chemotherapy should be attempted whenever possible, and could act as a prognosticator.SummaryOrbital preservation strategy can be attempted even in case of limited extraconal fat invasion. When extraocular muscles, massive extraconal fat, lateral wall of the lacrimal sac, eyelids or even optic nerve/globe are invaded, a conservative procedure cannot be offered. Induction chemotherapy and postoperative radiotherapy are invaluable tools for maintaining oncological outcome while preserving ocular function. Frozen section should be used for guiding surgical procedures in borderline situations
Evaluating survival after allogeneic bone marrow transplant for chronic myeloid leukaemia in chronic phase: a comparison of transplant versus no-transplant in a cohort of 258 patients first seen in Italy between 1984 and 1986
No full textA prospective comparison of alpha-IFN and conventional chemotherapy in Ph+ chronic myeloid leukemia. Clinical and cytogenetic results at 2 years in 322 patients
No full textConfirmation and improvement of Sokal's prognostic classification of Ph+ chonic myeloid leukemia: the value of early evaluation of the course of the disease.
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Is the Da Vinci Xi system a real improvement for oncologic transoral robotic surgery? A systematic review of the literature
No full textIn this paper, we reviewed the current literature about TORS procedures performed with Xi system and we discussed the pros and cons of this robotic system comparing it to the previous Si model. A systematic literature review was conducted using the PubMed, Scopus, Web of Science and Cochrane databases for adequate published studies about TORS procedure performed with da Vinci Si and Xi models. Five papers on the TORS-Xi procedures met our inclusion and exclusion criteria. These papers showed results based on 74 subjects (mean age 60.51 ± 4.55 years old). The most common TORS procedure was performed to address the oropharynx (65 procedures). One case (1.35%) of a tongue base tumor was converted into a transmandibular approach. One subject (1.35%) had a positive margin, while two subjects (2.7%) had close/uncertain margins at final histology. Nine papers on the TORS-Si procedures met our inclusion and exclusion criteria. These papers showed results based on 128 subjects (mean age 59.79 ± 5.93 years old). The most common TORS procedure was performed to address the oropharynx (90 procedures). Three procedures (2.34%) were aborted due to inadequate exposure of the tumor. None of the subject had positive margins, while three subjects (2.34%) had close/uncertain margins at final histology. Despite its improved vision, easier docking and narrower robotic arms, the da Vinci Xi system has structural peculiarities that limit its applications for certain TORS procedures
Experience in Transoral Robotic Surgery in Pediatric Subjects: A Systematic Literature Review
No full textPediatric transoral robotic surgery (TORS) has improved from 2007 to 2020, widening
its indications and feasibility. This article aims to systematically analyze the procedures
performed from the first use until the current year, observing their evolution over time. A
systematic literature review was performed using PubMed, Scopus, Web of Science, and
Cochrane databases between March 1, 2000, and April 1, 2020. We selected studies
that were written only in English and were performed in live human subjects. About
16 studies were found with a total of 73 subjects treated, among them 41 were men
and 32 were women with an average age of 6.8 ± 4.99 years. There have been four
(5.47%) conversions. Both functional and benign-malignant diseases have been treated
in the series. Eleven (15.06%) pre-operative tracheostomy and zero post-operative
tracheostomy were performed. The bleeding data was only reported in 9 studies and was
<50 ml. Only one (1.36%) intra-operative complication and 10 (12.32%) postoperative
complications were reported. We consider the TORS procedures in pediatric subjects
safe, feasible and with good surgical outcomes up to the laryngeal region
“Very late” relapses in Hodgkin’s disease patients: a rare but real phenomenon
No full textIn the past several decades, scientific and therapeutic advances have transformed Hodgkin's disease from a uniformly fatal illness to one that can be treated with the expectation of long-term remission or cure in the majority of cases. Because patients now survive for long periods after treatment, various late complications are being identified. Among patients with such late complications, some have been reported to experience "very late" relapses (> 10 years). Here we document recurrences in three patients with Hodgkin's disease more than 10 years after remission
Prospective confirmation of a prognostic classification for Ph+ chronic myeloid leukemia
No full textDr. Duane M. Jackson, Morehouse College, July 2011
No full textThis video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer
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