196,715 research outputs found
sj-docx-1-jmh-10.1177_15579883241239552 – Supplemental material for Men With Type II Diabetes in Peru: The Role of Masculine Gender Norms in the Perception of Family Support
No full textSupplemental material, sj-docx-1-jmh-10.1177_15579883241239552 for Men With Type II Diabetes in Peru: The Role of Masculine Gender Norms in the Perception of Family Support by Isabella Ferrazza and M. Amalia Pesantes in American Journal of Men's Health</p
Comments on the paper "End-tidal pressure of CO(2) and exercise performance in healthy subjects" by Bussotti M, Magrì D, Previtali E, Farina S, Torri A, Matturri M, Agostoni P (2008)
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Il gel piastrinico nel trattamento del “piede diabetico”: esperienza preliminare
No full textIL GEL PIASTRINICO NEL TRATTAMENTO DEL “PIEDE DIABETICO”: ESPERIENZA PRELIMINARE
Massimo Chiaretti*, Giancarlo Ferrazza+, Rita Maria Fracassi@ , Andrea Negro°, Domenico Tuscano*
(*) Dipartimento di Chirurgia Generale, Specialità Chirurgiche e Trapianti d’Organo “Paride Stefanini” Azienda Policlinico Umberto I, Università degli Studi di Roma “La Sapienza”
(+ ) Servizio di Immunoematologia e Medicina Trasfusionale Azienda Policlinico Umberto I, Università degli Studi di Roma “La Sapienza”
(@) Servizio di Immunoematologia IRCCS Ospedale Bambino Gesù, sede di Roma.
(°) Azienda S. Andrea, II Facoltà di Medicina e Chirurgia dell’Università degli Studi di Roma “La Sapienza”
La nostra esperienza evidenzia l’utilità del gel piastrinico (GP) nel trattamento ambulatoriale delle piaghe torpide della pianta del piede in paziente diabetico. Il GP guarisce in tempi prevedibili ulcerazioni torpide che richiedevano lunghissimi periodi di medicazioni complesse senza raggiungere il risultato prefissato. La nostra esperienza, analogamente ai risultati di altri autori, depone favorevolmente per questo trattamento. La metodica personalmente messa a punto prevede il curettage dopo disinfezione, l’inoculazione di 1 UI di insulina pronta alla base del cratere ulcerativo e quindi l’applicazione di 5 ml di GP con 1 ml di Trombina autologa attivata. L’applicazione può essere eseguita mediante un puntale spray o cannula a seconda delle esigenze dell’operatore o del tipo di lesione. In caso di ferite più piccole o man mano che la ferita in trattamento si riduce di ampiezza, il prodotto può essere aliquotato e congelato per successive somministrazioni. Il GP e la trombina vanno spalmati in situ e su un supporto inerte riassorbibile di acido ialuronico (Hialogel) con il quale si zaffa la cavità e che impedisce la dispersione della parte liquida e non completamente gelificabile, ricca dei fattori di crescita (PDGF, TGF, EGF, ed altri). Il rapporto strettamente collaborativo tra dermatologo, chirurgo, ortopedico, immunotrasfusionista, diabetologo e cardiologo, risolve questa problematica con un approccio multidisciplinare. Lo stretto coordinamento tra centro trasfusionale ed ambulatorio chirurgico evita inutili attese al Paziente, accorcia i tempi di esecuzione della medicazione, abbatte i costi per l’impiego di materiali e alla lunga diventa conveniente rispetto al tradizionale trattamento.Our study proves the usefulness of platelet gel in the treatment of the diabetic foot. We started in January 2006 to treat diabetic wounds of the foot in the outpatients’ surgical department with encouraging results. Despite its expensive and complex preparation, the platelet gel is useful and convenient because it succeeds in shortening the ambulatory treatment period. Besides, in our opinion, the multidisciplinary approach of this treatment is rather important: actually, it implies the cooperation of dermatologist, surgeon, orthopaedist, immunologist, diabetologist and, if necessary, the cardiologist. That is why it reduces wastes of work-time and the expenses for consultants, medications and dressing material
Cardiopulmonary exercise testing in the functional and prognostic evaluation of patients with pulmonary diseases
No full textExercise testing is increasingly utilized to evaluate the level of exercise intolerance in patients with lung and heart diseases. Cardiopulmonary exercise testing (CPET) is considered the gold standard to study a patient's level of exercise limitation and its causes. The 2 CPET protocols most frequently used in the clinical setting are the maximal incremental and the constant work rate tests. The aim of this review is to focus on the main respiratory diseases for which exercise tolerance is indicated; for example, chronic obstructive pulmonary disease, interstitial lung disease, primary pulmonary hypertension and cystic fibrosis. This review also focuses on the variables/indices that are utilized in the functional and prognostic evaluation. The recognition of abnormal response patterns of ventilatory, cardiac and metabolic limitation to exercise may help in the diagnostic evaluation. In addition, CPET indexes can provide important functional and prognostic information regarding patients with pulmonary disease. Exercise indices, such as peak oxygen uptake (V'O 2 peak), ventilatory equivalents for carbon dioxide production (V'E-/V'CO2) and arterial oxygen saturation (S pO2), have in fact proven to be better predictors of prognosis than lung function measurements obtained at rest. Moreover, useful information on the effects of therapeutic interventions may be obtained by CPET by studying the changes in endurance capacity during high-intensity constant work rate protocols. Copyright © 2009 S. Karger AG
In orbit performance of the UNISAT terrestrial technology solar panels
No full textThe UNISAT microsatellite solar panels are manufactured using a terrestrial technology solar panel fabrication technique, with some modification to improve reliability and make the system withstand the launch and space environment. The solar cells are encapsulated between two layers made of a special sunlight transparent polymer, resistant to UV exposure and with very good mechanical properties. This technology, available at Eurosolare. has been employed for many years in terrestrial applications, including extreme environments, such as the Antartic polar region and Sahara desert, but there is no space flight experience. The ground tests performed for the UNISAT solar panels predict a reliable lifetime of about one year and data collected show also their good electrical performance in orbit. The UNISAT experience shows that in low cost space missions terrestrial technology solar panels can be employed, leaving the designer free to choose the most appropriate solar cell size and to cut down costs and development time
Exercise intolerance at high altitude (5050 m): critical power and W'
No full textThe relationship between work rate (WR) and its tolerable duration (t(LIM)) has not been investigated at high altitude (HA). At HA (5050 m) and at sea level (SL), six subjects therefore performed symptom-limited cycle-ergometry: an incremental test (IET) and three constant-WR tests (% of IET WR(max), HA and SL respectively: WR(1) 70±8%, 74±7%; WR(2) 86±14%, 88±10%; WR(3) 105±13%, 104±9%). The power asymptote (CP) and curvature constant (W') of the hyperbolic WR-t(LIM) relationship were reduced at HA compared to SL (CP: 81±21 vs. 123±38 W; W': 7.2±2.9 vs. 13.1±4.3 kJ). HA breathing reserve (estimated maximum voluntary ventilation minus end-exercise ventilation) was also compromised (WR(1): 25±25 vs. 50±18 l min(-1); WR(2): 4±23 vs. 38±23 l min(-1); WR(3): -3±18 vs. 32±24 l min(-1)) with near-maximal dyspnea levels (Borg) (WR(1): 7.2±1.2 vs. 4.8±1.3; WR(2): 8.8±0.8 vs. 5.3±1.2; WR(3): 9.3±1.0 vs. 5.3±1.5). The CP reduction is consistent with a reduced O(2) availability; that of W' with reduced muscle-venous O(2) storage, exacerbated by ventilatory limitation and dyspnea. Copyright © 2011 Elsevier B.V. All rights reserved
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