1,721,202 research outputs found
Uncertainty in economic evaluations: implications for healthcare decisions
Get PDFOnzekerheid rondom kosteneffectiviteitsanalyse gezondheidszorg in kaart gebracht Wel of niet vergoeden? Die vraag wordt bij nieuwe behandelingen in de gezondheidszorg steeds belangrijker, en daarom spelen kosteneffectiviteitsanalyses een steeds belangrijkere rol. Leyla Mohseninejad verkende in haar promotieonderzoek manieren om de onzekerheid rondom zulke analyses in kaart te brengen en ze vertaalde deze theoretische concepten naar besluitvorming. Mohseninejad legt uit dat een kosteneffectiviteitsanalyse de extra kosten van een nieuwe behandeling koppelt aan de gezondheidswinst ten opzicht van de oude behandeling. Deze berekening wordt bemoeilijkt doordat de kosten en de gezondheidswinst lastig te voorspellen zijn, bijvoorbeeld doordat er gegevens uit verschillende bronnen worden gecombineerd of doordat er gewoonweg nog te weinig gegevens zijn. Dat betekent dat beslissingen die gebaseerd zijn op zo’n analyse, ook onzeker zijn. De promovenda paste enkele theoretische kostenberekeningsmethoden toe op concrete voorbeelden uit de gezondheidszorg, namelijk preventie van depressie door een “e-health”-behandeling, screening op coeliakie (glutenintolerantie) bij mensen met een prikkelbare darm, behandeling van uitgezaaide darmkanker en de behandeling van schimmelinfecties bij mensen met een ernstig verminderde afweer. Ze concludeert onder andere dat het mogelijk is, door een systematische analyse van kosten en opbrengsten in de tijd, om het tijdstip vast te stellen waarop verder verlengen van de evaluatieperiode van een bepaald duur geneesmiddel niet meer opweegt tegen de kosten. Deze resultaten kunnen zorgverzekeraars mogelijk helpen bij het vaststellen van een nieuwe leidraad
ADVISHE. Reporting Tool+ Website
No full textAssessment of the Validation Status of Health-Economic decision models (AdViSHE) is a tool that provides model users with a structured view into the validation status of the model, according to a consensus on what good model validation entails. Reporting Tool for Model validation. Available from https://advishe.wordpress.com/author/advishe/ Result from my ZONMW grants. VIMP to support implementation of AdViSHE, an instrument for Assessment of the Validation Status of Health Economic decision models (ZONMW project 1520020501) https://www.zonmw.nl/nl/onderzoek-resultaten/geneesmiddelen/programmas/project-detail/doelmatigheidsonderzoek-farmacotherapie/vimp-to-support-implementation-of-advishe-an-instrument-for-assessment-of-the-validation-status-of/ Disease models used for decisions on expensive drugs: a new instrument to enable structured model assessment (ZonMw-project 152002050) https://www.zonmw.nl/nl/onderzoek-resultaten/geneesmiddelen/programmas/project-detail/doelmatigheidsonderzoek-farmacotherapie/disease-models-used-for-decisions-on-expensive-drugs-a-new-instrument-to-enable-structured-model-as/ In the meantime more than 50 papers have used this tool, and many more referred to it: https://advishe.wordpress.com/reference-list/ It is mentioned in two national guidelines for economic evaluation. (Australia and the Netherlands) It has an active twitter account: https://twitter.com/AdViSHE?ref_src=twsrc%5Etfw%7Ctwcamp%5Etweetembed%7Ctwterm%5E1313377972569739265%7Ctwgr%5E%7Ctwcon%5Es1_&ref_url=https%3A%2F%2Fadvishe.wordpress.com%2F2020%2F10%2F06%2Fa-crash-course-to-advishe-now-available-on-twitter%2F (kept active by Isaac Corro Ramos, Erasmus University and team member
The cost-effectiveness of laparoscopic adjustable gastric banding in the morbidly obese adult population of Australia
No full textBackground: To examine the cost-effectiveness of providing laparoscopic adjustable gastric banding (LAGB) surgery to all morbidly obese adults in the 2003 Australian population
Comparative efficiency of health systems, corrected for selected life style factors: Final report
Get PDFThe MACELI (Macro Cost Effectiveness corrected for Lifestyle) project studied the cost-effectiveness of European health systems, and the impact of differences in lifestyle, specifically smoking, overweight and alcohol consumption.Baseline analyses without standardizing for lifestyle showed on average more health spending was associated with better health. This effect was clearest for countries with lower levels of spending. Standardization towards a better lifestyle meant an upward shift of the health production function, but did not much alter the comparative efficiency of countries.The study covered the EU-28 Member States, Iceland, and Norway. Individual-level data were used to describe lifestyle across age and gender and to analyse its impact on health outcomes and health care use. Health outcomes and health spending were standardized for differences in lifestyle using a lifetable model (reference year 2010).Results were put into further perspective by additional qualitative research and through several sensitivity analyses, including an indirect disease-based approach. Finally, a systematic literature review was performed to investigate potential interventions to achieve lifestyle changes.Several shortcuts were taken to allow consistent estimates across a large number of countries, which imply that the results should be interpreted with care
Comparative efficiency of health systems, corrected for selected life style factors: Final report
Get PDFThe MACELI (Macro Cost Effectiveness corrected for Lifestyle) project studied the cost-effectiveness of European health systems, and the impact of differences in lifestyle, specifically smoking, overweight and alcohol consumption.Baseline analyses without standardizing for lifestyle showed on average more health spending was associated with better health. This effect was clearest for countries with lower levels of spending. Standardization towards a better lifestyle meant an upward shift of the health production function, but did not much alter the comparative efficiency of countries.The study covered the EU-28 Member States, Iceland, and Norway. Individual-level data were used to describe lifestyle across age and gender and to analyse its impact on health outcomes and health care use. Health outcomes and health spending were standardized for differences in lifestyle using a lifetable model (reference year 2010).Results were put into further perspective by additional qualitative research and through several sensitivity analyses, including an indirect disease-based approach. Finally, a systematic literature review was performed to investigate potential interventions to achieve lifestyle changes.Several shortcuts were taken to allow consistent estimates across a large number of countries, which imply that the results should be interpreted with care
Comparative efficiency of health systems, corrected for selected life style factors: Final report
Get PDFThe MACELI (Macro Cost Effectiveness corrected for Lifestyle) project studied the cost-effectiveness of European health systems, and the impact of differences in lifestyle, specifically smoking, overweight and alcohol consumption.Baseline analyses without standardizing for lifestyle showed on average more health spending was associated with better health. This effect was clearest for countries with lower levels of spending. Standardization towards a better lifestyle meant an upward shift of the health production function, but did not much alter the comparative efficiency of countries.The study covered the EU-28 Member States, Iceland, and Norway. Individual-level data were used to describe lifestyle across age and gender and to analyse its impact on health outcomes and health care use. Health outcomes and health spending were standardized for differences in lifestyle using a lifetable model (reference year 2010).Results were put into further perspective by additional qualitative research and through several sensitivity analyses, including an indirect disease-based approach. Finally, a systematic literature review was performed to investigate potential interventions to achieve lifestyle changes.Several shortcuts were taken to allow consistent estimates across a large number of countries, which imply that the results should be interpreted with care
Comparative efficiency of health systems, corrected for selected life style factors: Final report
Get PDFThe MACELI (Macro Cost Effectiveness corrected for Lifestyle) project studied the cost-effectiveness of European health systems, and the impact of differences in lifestyle, specifically smoking, overweight and alcohol consumption.Baseline analyses without standardizing for lifestyle showed on average more health spending was associated with better health. This effect was clearest for countries with lower levels of spending. Standardization towards a better lifestyle meant an upward shift of the health production function, but did not much alter the comparative efficiency of countries.The study covered the EU-28 Member States, Iceland, and Norway. Individual-level data were used to describe lifestyle across age and gender and to analyse its impact on health outcomes and health care use. Health outcomes and health spending were standardized for differences in lifestyle using a lifetable model (reference year 2010).Results were put into further perspective by additional qualitative research and through several sensitivity analyses, including an indirect disease-based approach. Finally, a systematic literature review was performed to investigate potential interventions to achieve lifestyle changes.Several shortcuts were taken to allow consistent estimates across a large number of countries, which imply that the results should be interpreted with care
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