190 research outputs found
Le ragioni dell'interesse per la Biondini e primi percorsi di ricerca
No full textHo messo in evidenza la personalità di Arcangela Biondini, fondatrice del monastero di Arco, e i percorsi di ricerca avviati sulla sua oper
Le cas de la soeur Biondini
No full textho presentato il caso della monaca Arcangela Biondini: della sua fondazione ad Arco e della sua forte personalità contrapposta ai direttori spirituali che l'hanno guidat
L'Autobiografia di Arcangela Biondini. Studi e testo critico
No full textSi tratta dell'edizione critica dell'autobiografia della fondatrice Arcangela Biondini (1641-1712
Arcangela Biondini (1641-1712): l’autorità di una fondatrice
No full textla figura di Arcangela Biondini, fondatrice del monastero di Arco (TN) si presta per un'analisi dell'esercizio di autorità femminile alla fine del'60
Maria Arcangela Biondini (1641-1712) e il monastero delle Serve di Maria di Arco. Una fondatrice e un archivio
No full textLa vita e l'opera di Arcangela Biondini, fondatrice del monastero di Arco (TN
Seismic vulnerability of historical buildings: the Royal Palace of Naples
No full textThe paper deals with an extensive study concerning the application of an integrated multilevel methodology for the evaluation of the seismic vulnerability of the Royal Palace of Naples. In particular the paper focuses on the north-west wing of the Royal Palace of Naples. The first phase of the vulnerability evaluation, which consists in the application of the GNDT Level II method for the vulnerability index estimate and in the use of the vulnerability function for the damage index calculation, is presented. The applied methodology is suitable for a global vulnerability estimation of those structural typologies, such as historical monumental masonry building, characterized by complex structural configurations and proportions. Complementary in depth mechanical both localized and global investigations will be performed in succeeding phases
CA 19-9 serum levels in patients with end-stage idiopathic pulmonary fibrosis (IPF) and other interstitial lung diseases (ILDs): Correlation with functional decline
No full textIdiopathic pulmonary fibrosis presents a progressive and heterogeneous functional decline. CA 19-9 has been proposed as biomarker to predict disease course, but its role remains unclear. We assessed CA 19-9 levels and clinical data in end-stage ILD patients (48 IPF and 20 non-IPF ILD) evaluated for lung transplant, to correlate these levels with functional decline. Patients were categorized based on their rate of functional decline as slow (n = 20; ΔFVC%pred ≤ 10%/year) or rapid progressors (n = 28; ΔFVC%pred ≥ 10%/year). Nearly half of the entire patients (n = 32; 47%) had CA 19-9 levels ≥37kU/L. CA 19-9 levels in IPF were not different from non-IPF ILD populations, however, the latter group had a median CA 19-9 level above the normal cut-off value of 37 KU/l (60 [17-247] kU/L). Among IPF patients, CA 19-9 was higher in slow than in rapid progressors with a trend toward significance (33vs17kU/L; p = 0.055). In the whole population, CA19-9 levels were inversely related with ΔFVC/year (r = -0.261; p = 0.03), this correlation remained in IPF patients, particularly in rapid progressors (r = -0.51; p = 0.005), but not in non. Moreover, IPF rapid progressors with normal CA 19-9 levels showed the greater ΔFVC/year compared to those with abnormal CA 19-9 (0.95 vs. 0.65 L/year; p = 0.03). In patients with end-stage ILD, CA 19-9 may represent a marker of disease severity, whereas its level is inversely correlated with functional decline, particularly among IPF rapid progressors
Preference-based service life design of floating wind structures
No full textFloating wind farms are a promising solution for offshore wind energy production in deep waters. However, the design optimisation process of these farms is difficult due to their complex and multidisciplinary nature. Furthermore, current optimisation methods: 1) ignore and/or provide no insight into the dynamic interplay between the preference-dominated management domain and the object-performance-dominated engineering domain; 2) are limited to evaluating potentially sub-optimal design alternatives; 3) contain fundamental aggregation modelling errors; 4) do not return a single optimal design point. This paper presents an optimisation framework that overcomes these shortcomings and enables truly integrative multi-objective design optimisation. It includes a surrogate model that interacts with the wind turbine simulation tool OpenFAST to enable preliminary design of the structure’s mooring system. Applied to a demonstration project and validated against real projects in a maritime contractor environment, the workflow shows improvements in tender performance and added value over single-sided cost optimisations.Offshore EngineeringReal Estate ManagementEngineering Structure
Multi-stakeholder service life design for rail level crossings
No full textImprovement in rail asset safety, comfortability and serviceability is gaining importance. This requires effective service life management by incorporating multi-stakeholder desires in the early design stage. Typical stakeholders are asset owners, train users and maintenance service providers. To allow for this change, the traditional single-sided engineering mechanics track design approach requires a shift towards an integrative design approach that best fits for common purpose while assuring continuous rail asset performance. Within the current paper, a multi-objective simulation-based optimization methodology that combines finite element modeling with preference function modeling is proposed to integrate multi-stakeholder preferences into the service life design. The applicability of the methodology is demonstrated in a design case for level crossings. It is shown that integrating specific stakeholders’ preferences will substantially influence the optimal track design configuration, allowing the level crossing design to be managed focusing on best fit for common purpose rather than on mechanical behavior only.Integral Design & ManagementReal Estate ManagementEngineering Structure
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