8 research outputs found
Ultrasound biomicroscopy value in evaluation of restoration of ciliary muscles contractility after cataract extraction
No full textAyser Abd El-Hameed Fayed Ophthalmology Department, Faculty of Medicine, Banha University, Banha, Egypt Purpose: To assess the changes in the contractility of the ciliary muscle in eyes with presbyopia before and after phacoemulsification and intracapsular lens implantation using ultrasound biomicroscopy (UBM). Patients and methods: This prospective study included 50 eyes of 30 consecutive subjects operated at the Department of Ophthalmology. Patients with any ocular disorder affecting visual acuity, corneal surface irregularities, had posterior capsular perforation or intensive postoperative corneal edema, or were <35 years of age, were excluded. A clear corneal phacoemulsification and posterior chamber intraocular lens were implanted. UBM was performed with and without instilling 2% pilocarpine. Ciliary body axial length (CBAXL), anterior chamber depth, and angle were measured before and 1 month after surgery. Results: The CBAXL showed a greater contractile shortening (P<0.5), with centripetal, contractile shift of ciliary muscle mass. Conclusion: After phacoemulsification and intracapsular lens implantation, ultrasonic biomicroscopy showed significant centripetal movement of the ciliary body compared with that before surgery. This shows that a lenticular sclerotic component may influence both lens movement and the contractility of the ciliary muscle and is believed to be related to the presbyopia. Keywords: ciliary body, presbyopia, accommodation, intraocular lens, pilocarpin
Efficacy of transepithelial corneal collagen crosslinking for keratoconus: 12-month follow-up
No full textMohamed A Heikal, Tarek Tawfik Soliman, Ayser Fayed, Abdelmonem M Hamed Department of Ophthalmology, Benha University, Benha, Egypt Purpose: To evaluate the efficacy of transepithelial corneal collagen crosslinking (TE-CXL) in patients with progressive keratoconus. Patients and methods: This is a prospective interventional consecutive study carried out on 30 eyes of 18 patients with progressive keratoconus who underwent TE-CLX using both ParaCel™ (riboflavin 0.25%, hydroxy propyl methyl cellulose, NaCl, ethylenediaminetetraacetic acid [EDTA], Tris, and benzalkonium chloride) and vibeX-Xtra (riboflavin 0.22%, phosphate-buffered saline solution). The procedure was carried out at Ebsar Eye Center in Egypt in the period from 2012 to 2014. The follow-up visits were scheduled on days 1, 3, 6, and 12 months after treatment. Results: There were statistically significant improvements (P<0.001) in the mean best-corrected visual acuity (0.54±0.22 preoperatively vs 0.61±0.19 at 12 months postoperatively), the mean manifest refraction spherical equivalent (MRSE; -6.16±3.90 diopters [D] preoperatively and -5.91±3.72 D at 12 months postoperatively), and the mean preoperative corneal astigmatism (-3.39±2.11 D preoperatively and -2.46±2.60 D at 12 months postoperatively). Conclusion: TE-CXL could halt the progression of keratoconus in adult patients. TE-CXL resulted in a statistically significant improvement in best-corrected visual acuity, manifest refraction, refractive and corneal astigmatism and K values in keratoconus patients at the 12-month follow-up. Larger sample sizes and longer follow-ups are required in order to make meaningful conclusions. Keywords: corneal astigmatism, refractive astigmatism, transepithelial crosslinking, progressive keratoconu
Evaluation of the filtering bleb and its relation to an intrascleral aqueous drainage route after trabeculectomy using ultrasound biomicroscopy
No full textPurpose
The aim of this study was to evaluate the relationship between filtering bleb parameters (height, extent) and the wideness of the aqueous drainage route beneath the scleral flap using ultrasound biomicroscopy (UBM) in patients who have undergone trabeculectomy with and without mitomycin-C (MMC).
Design
This was a prospective interventional observation uncontrolled study.
Patients and methods
A total of 30 patients undergoing 30 glaucoma filtering surgeries were assessed for at least 6 months using UBM to evaluate the bleb reflectivity, the visibility of the route under the scleral flap, the bleb height, and the extent in correlation with the mean intraocular pressure. Patients were divided into two groups: group A included 15 eyes in which trabeculectomy was performed without MMC and group B included 15 eyes in which trabeculectomy was performed with MMC (0.4%) applied for 2 min.
Results
The reflectivity inside the filtering bleb showed a significant correlation with the maximal width of the aqueous drainage route and the maximal height and the extent of the bleb. Furthermore, the bleb function was significantly associated with its UBM image in eyes trabeculectomized with adjunctive MMC.
Conclusion
The study concluded that the internal structure of the bleb can be a more sensitive predictor of the outcome of filtering surgery
The Effect of Massage, Acupressure and Reflexology on Restless Legs Syndrome Severity and Sleep Quality in Patients Receiving Haemodialysis Treatment: A Systematic Review and Meta-Analysis
No full textAim: This study aimed to review massage, acupressure and reflexology interventions applied to haemodialysis patients with restless legs syndrome and to examine the effects of these interventions on sleep quality. Design: A systematic review and meta-analysis. Data Sources: A systematic literature search was conducted on databases ScienceDirect, Web of Science, Cochrane Central Register of Controlled Trials, EBSCO and PubMed. Methods: The Modified Jadad scale was used. The statistical analysis was conducted using the Stata 15.0 software, with the aim of evaluating heterogeneity between studies using both chi-square and I2 statistics. The risk of bias in the included studies was assessed using both the Cochrane risk of bias assessment tool and statistical tests. A funnel plot was used to detect potential publication bias, which is indicated by an asymmetry in the plot. The Egger regression test was also performed to evaluate publication bias. Results: Twelve studies were selected for the meta-analysis. All studies included in this meta-analysis were of good quality. In the subgroup analysis, it was determined that massage and acupressure reduced the severity of restless legs syndrome as a result of the intervention, while reflexology had no effect. Interventions did not affect the sleep quality of patients. Restless legs syndrome severity was significantly reduced in studies using oil and in studies that intervened for more than 15 min per session. Conclusion: Interventions applied to haemodialysis patients with restless legs syndrome can reduce the severity of restless legs syndrome. It is recommended to conduct randomised controlled trials that determine the effects of methods on restless legs syndrome severity and sleep quality in haemodialysis patients. © 2025 The Author(s). Nursing Open published by John Wiley & Sons Ltd
Vitamin D levels in patients with Behçet’s disease: Significance and impact on disease measures
No full textAbstractAim of the workThis study aimed to investigate serum levels of vitamin D in patients with Behçet’s disease (BD) and to evaluate their relationship to disease activity as well as different disease measures.Patients and methodsForty-two patients with BD were enrolled into this study. These patients were subjected to detailed history taking, thorough clinical examination including assessment of disease activity according to Behçet’s Disease Current Activity Form (BDCAF) score and performed laboratory investigations including erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), serum calcium, serum phosphorus and serum alkaline phosphatase. Serum 25-hydroxyvitamin D (vitamin D) levels were determined using Enzyme-Linked-Immunosorbent Assay (ELISA). A control group of 41 age and sex matched healthy controls was also included.ResultsThe mean level of 25-hydroxyvitamin D (30.65±12.87ng/ml) was significantly decreased in BD patients compared to the controls (37.98±15.76ng/ml) (p=0.02). Significant negative correlations of serum vitamin D levels with patients’ ages (p=0.03), ESR (p<0.001), CRP (p<0.001) and BDCAF (p=0.003) were found; whereas, there was no significant correlation with disease duration (p=0.6). In multivariate regression analysis age (p=0.02), colchicine therapy (0.008), ESR (0.02) and CRP (0.03) were found to be the independent effectors on vitamin D serum levels.ConclusionSerum levels of vitamin D were significantly lower in BD patients compared to controls. Associations were found between vitamin D levels and age, BDCAF as well as ESR and CRP in BD patients. Low vitamin D may predispose BD patients to active disease, especially in older subjects
Efficacy of transepithelial corneal collagen crosslinking for keratoconus: 12-month follow-up
No full textEvaluation of anterior segment changes using ultrasound biomicroscopy following phacoemulsification and implantation of one-piece and three-piece intraocular lenses in high myopia
No full textAim
The aim of this research was to study the performance of the implanted one-piece and three-piece intraocular lenses (IOLs) in relation to the enlarged diameters of the capsular bags of the highly myopic eyes.
Patients and methods
Patients were randomly divided into two groups: group A included 15 eyes that underwent phacoemulsification with implantation of one-piece IOLs, and group B included 15 eyes that underwent phacoemulsification with implantation of three-piece IOLs. All patients included in this study were high myopes with axial length greater than 26.5 mm. All eyes were planned for clear lens extraction or cataract extraction.
Results
In group A, a statistically significant negative correlation was found between the diameters of the capsular bags and the diameters of the implanted one-piece IOLs. The correlation coefficient (r) is −0.56. In group B, a statistically significant positive correlation was found between the diameters of the capsular bags and the diameters of the implanted three-piece IOLs. The correlation coefficient (r) is 0.86.
Conclusion
The study of this correlation is to help in answering an important question − that is, does one diameter IOL fit all capsular bags? The statistical analyses in both groups point to a statistically significant correlation between the diameters of the capsular bags and the diameters of the implanted IOLs in both groups A and B, which demonstrates the absence of fitting of both sorts of IOLs in relation to the enlarged capsular bags of the highly myopic eyes − i.e. it focuses on the divergence between the size of the IOLs and that of the capsular bag
Vascular endothelial growth factor and subclinical atherosclerosis by carotid ultrasonography in Egyptian patients with Behçet’s disease
No full textAbstractAim of the workThis study aimed to investigate serum levels of vascular endothelial growth factor (VEGF) and to measure common carotid intima media thickness (cc-IMT) in Egyptian patients with Behçet’s disease (BD) to evaluate their relations to disease activity and different clinical manifestations.Patients and methodsSeventy patients with BD and 70 healthy controls participated in this study. Behçet’s disease patients were subjected to detailed history taking, thorough clinical examination, disease activity assessment using the BD Current Activity Form (BDCAF) and laboratory investigation. Vascular endothelial growth factor levels were measured using ELISA. The carotid arteries were assessed for cc-IMT and plaques with a carotid high-resolution B-mode ultrasound.ResultsThe mean cc-IMT showed a significant difference in BD patients compared to controls (p<0.011). Three BD patients had plaques (4.3%). There were significant correlations of cc-IMT with disease duration (p<0.001), systolic blood pressure (BP) (p=0.029), diastolic BP (p=0.041), total cholesterol (p<0.001) and LDL (p<0.001) and insignificant correlation with BDCAF (p=0.054). There was a significant elevation of VEGF levels (p<0.001) in BD patients compared to controls. VEGF levels showed significant correlations with ESR (p=0.14), CRP (p<0.001) and BDCAF (P=0.02), while there was an insignificant correlation with cc-IMT (p=0.107).ConclusionBD patients have ultrasonographic evidence of subclinical atherosclerosis which was associated with increasing age, longer disease duration, elevated systolic and diastolic BP, total cholesterol and LDL. Elevated VEGF showed statistically significant positive correlations with BDCAF and thus can be used as a marker of disease activity and/or therapeutic targets in BD patients
