26,134 research outputs found
Anmerkungen : zu den "Beiträgen zur Geologie der Rheinpfalz, II. Teil" von O.M. Reis in den "Mitteilungen der Pollichia", 1935, Bd. IV
No full textvon Oberlehrer a.D. Ph. Fauth, Grünwald bei Münche
Opposing Effects of Neuronal Activity on Structural Plasticity
No full textThe connectivity of the brain is continuously adjusted to new environmental influences by several activity-dependent adaptive processes. The most investigated adaptive mechanism is activity-dependent functional or synaptic plasticity regulating the transmission efficacy of existing synapses. Another important but less prominently discussed adaptive process is structural plasticity, which changes the connectivity by the formation and deletion of synapses. In this review, we show, based on experimental evidence, that structural plasticity can be classified similar to synaptic plasticity into two categories: (i) Hebbian structural plasticity, which leads to an increase (decrease) of the number of synapses during phases of high (low) neuronal activity and (ii) homeostatic structural plasticity, which balances these changes by removing and adding synapses. Furthermore, based on experimental and theoretical insights, we argue that each type of structural plasticity fulfills a different function. While Hebbian structural changes enhance memory lifetime, storage capacity, and memory robustness, homeostatic structural plasticity self-organizes the connectivity of the neural network to assure stability. However, the link between functional synaptic and structural plasticity as well as the detailed interactions between Hebbian and homeostatic structural plasticity are more complex. This implies even richer dynamics requiring further experimental and theoretical investigations
Towards a Christian Philosophy
No full textAuthor did not sign the LAC Non-Exclusive License form.The relationship between philosophy and Christianity has, of course, a long history, as do the discussions of that relationship. My own position is not dissimilar to that of many of the early Church Fathers, though of course that position must be elaborated differently for various historical and personal reasons, and hopefully enriched by attention to the history of Western philosophy. As with all such relations, one's understanding of this relation has a lot to do with one's understanding of the terms involved. To promote the possibility of "Christian philosophy" is also to comment on that "and" which might be understood to relate two otherwise distinct and irreconcilable terms. In the end I claim this "and" must be understood as that "love" which defines philosophy as the "love of wisdom" (and finally, the wisdom of love), and does so in terms which (almost) merge-with the surprising assistance of such thinkers as Martin Heidegger, Jacques Derrida, and Paul Ricoeur-with those of the Church Fathers cited. On the one hand, I intend nothing but the historical, orthodox, and catholic understanding of Christianity, especially with regard to the central figure of Jesus the Christ, the Trinitarian God whom He embodies, represents, and reveals, and the Scriptures given as The Bible. On the other hand, I present the specifically philosophical pertinence of this unique Person as such emerges from the texts of the "philosophers" considered, and in a manner which I claim does not force the issue by reading into their texts what is not there. Attending to a (Christian) philosophical reflection on (Christian) philosophy also offers elaborations of inherited doctrines, both Christian and philosophical, including a way to read and think unique to the outcome. Such is the adventure of this current work
Vom Fleischackerloch bei Landstuhl
No full textRudolf Drumm, Philipp Fauth, Otto Löhr, Jakob Weber, Josef Sprissle
The formation of multi-synaptic connections by the interaction of synaptic and structural plasticity and their functional consequences
No full textCortical connectivity emerges from the permanent interaction between neuronal activity and synaptic as well as structural plasticity. An important experimentally observed feature of this connectivity is the distribution of the number of synapses from one neuron to another, which has been measured in several cortical layers. All of these distributions are bimodal with one peak at zero and a second one at a small number (3-8) of synapses. In this study, using a probabilistic model of structural plasticity, which depends on the synaptic weights, we explore how these distributions can emerge and which functional consequences they have. We find that bimodal distributions arise generically from the interaction of structural plasticity with synaptic plasticity rules that fulfill the following biological realistic constraints: First, the synaptic weights have to grow with the postsynaptic activity. Second, this growth curve and/or the input-output relation of the postsynaptic neuron have to change sub-linearly (negative curvature). As most neurons show such input-output-relations, these constraints can be fulfilled by many biological reasonable systems. Given such a system, we show that the different activities, which can explain the layer-specific distributions, correspond to experimentally observed activities. Considering these activities as working point of the system and varying the pre- or postsynaptic stimulation reveals a hysteresis in the number of synapses. As a consequence of this, the connectivity between two neurons can be controlled by activity but is also safeguarded against overly fast changes. These results indicate that the complex dynamics between activity and plasticity will, already between a pair of neurons, induce a variety of possible stable synaptic distributions, which could support memory mechanisms
The Christian Right and US Foreign Policy in the Twenty-first Century
No full textThe thesis discusses the role of the Christian Right in the US foreign policy decision making process. The research revealed that the Christian Right has long been fascinated with some international issues in general and US foreign policy in particular. The Christian Right’s interest in international issues increased markedly during years of the George W. Bush presidency. It successfully widened its activities from domestic social conservative issues to foreign policy issues by participating in, articulating and lobbying for its religious version of American foreign policy. In assessing the role of the Christian Right in US foreign policy making, this dissertation examines three aspects of US foreign policy, namely Israel, international religious freedom and global humanitarianism. Based on these aspects, the Christian Right is seen as skilled in framing and defining issues. The Christian Right seems effective in selecting and prioritizing international issues that have a reasonable chance of being selected by foreign policy decision makers, especially in Congress. Moreover, the Christian Right has shown its maturity in seeking engagement and cooperation with other organizations, secular and religious, in order to advance its international goals. Finally, in pursuing and conveying its international agenda, the Christian Right has adopted a more moderate and less overtly religious approach. Instead of using its traditional religious rhetoric, the Christian Right has successfully projected its foreign policy preferences into the conventional realist discourse of American foreign policy that is largely based on the objective of national interest and national security. Nevertheless, this study does not, in any way, conclude that the Christian Right was able to influence or determine the direction of US foreign policy and its outcomes; however, it does suggest that the Christian Right did contribute and have an impact on the formulation of some US foreign policy. As such, the research contends that the role of the Christian Right is similar to other interest group lobbies and that its perceived influence on US foreign policy should not be exaggerated. Finally, the research suggests that the emergence of the Christian Right as an actor in asserting its global agenda through US foreign policy can possibly provide an example of how religious beliefs and values can become a potential source of “soft power”. Together with the “climate of opinion” of the American public during the Bush administration, the “soft power” at domestic level could serve as a valuable new explanatory variable in understanding how the US foreign policy was formulated in the early 21st century
Sabbath, Psalms and Eucharist: Christopher Southgate considers Christian perspectives on the climate emergency
No full textThis is the author accepted manuscript. The final version is available from Green Christian via the URL in this record In this brief article I want to explore what resources Christian thought might offer the
climate emergency, and those challenged by the slowness with which the generation
with the power (my own) are addressing the huge challenges that are ever more
evidently unfolding on our planet
Dare We Call it a Christian Business Division?
No full textThe author in this article explores the question: What, if anything, distinguishes a Christian business program from a secular program? The author answers the question by suggesting some areas he believes should be distinctive. His purpose is to open up a dialogue that has not occurred at the program level, not to claim all that could be said about this topic. Most discussion has focused on the macro picture of Christian colleges or the micro picture of how one’s faith might impact how one teaches a certain discipline. The article looks at themes or emphases in business programs that aspire to describe themselves as Christian
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