3,037 research outputs found
Inducible heat shock protein 70, interleukin-18, and tumor necrosis factor alfa correlate with outcomes in spontaneous intracranial hemorrhage.
No full textFinding Hy-Brasil: The Gateway Between Reality And Unreality
No full textThrough Irish history, different spiritual demands in specific historical moments impacts on the legends of Hy-Brasil. In turn, the stories of Hy-Brasil reflects the history of Ireland through its possible position, appearances, items events, viewpoints gateways and monuments. The project is to use the history of Hy-Brasil, a mystical island of Ireland, to explore the architecture of myth, which are expected to be triggered and formed by the current situation of Ireland. It looks to design a pragmatic space by providing a gateway to the mythic island of Hy-Brasil. Siting on the north end the Ireland, the Lough Foyle in Donegal, the project constructs an architectural artifact out of a particular strata of Ireland’s specific geology and monumental landscape to take people into the imagination and expectation of perceive the Irish mythology.The Berlage Post-MSc in Architecture and Urban Desig
A 5-GHz fully integrated low-power wide-tuning-range CMOS LC VCO
No full text[[abstract]]A 5-GHz-band monolithic LC differential voltage-controlled oscillator (VCO) with low-power consumption and wide-tuning-range was designed and implemented using a standard 0.18-mu m CMOS technology. Low-power consumption is achieved by maximizing the equivalent parallel resistance of the LC tank, while wide-tuning-range is achieved by minimizing the summed parasitic capacitance of the differential inductor and the cross-coupled PMOS transistors pair. The LC VCO achieves a wide-tuning-range of 14.1% (from 4.95 to 5.7 GHz) with a low-power dissipation of 1.5 mW. The measured phase noise is -111.1 dBc/Hz at 1-MHz offset. The corresponding figure-of-merit (FOM') of the VCO is -166.8 dBc/Hz, which is comparable with, or even better than, those of the reported state-of-the-art CMOS LC VCOs in 5-GHz-band. The chip area is only 630 x 730 mu m(2) excluding the test pads. (C) 2008 Wiley Periodicals, Inc.[[note]]SC
Molecular dynamics simulations to investigate the relationship between the structural stability and amyloidogenesis of the wild-type and N-terminal hexapeptide deletion Delta N6 beta 2-microglobulin
No full textMolecular Dynamics Simulations to Investigate the Aggregation Behaviors of the A beta(17-42) Oligomers
No full textWalnut-Derived Peptide Activates PINK1 via the NRF2/KEAP1/HO-1 Pathway, Promotes Mitophagy, and Alleviates Learning and Memory Impairments in a Mice Model
No full textMitophagy has a pivotal protective function in the pathogenesis of neurological disorders. However, the mechanism of its modulation remains elusive, especially in PINK1-mediated mitophagy. Here, we investigated the neuroprotective effects of a walnut-derived peptide, YVLLPSPK, against scopolamine-induced cognitive deficits in mice and explored the underlying PINK1-mediated mitophagy mechanisms in H2O2-treated HT-22 cells. Using the Morris water maze, we showed that YVLLPSPK relieved the cognitive deficiency by alleviating oxidative stress. Mitochondrial morphology was observed in mice hippocampal tissues using transmission electron microscopy (TEM). Both Western blot and immunofluorescence analysis illustrated YVLLPSPK promoted the expression of mitophagy-related proteins and activated the NRF2/KEAP1/HO-1 pathway. Subsequently, an NRF2 inhibitor (ML385) was used to verify the contribution of the YVLLPSPK-regulated NRF2/KEAP1/HO-1 pathway in PINK1-mediated mitophagy in H2O2-treated HT-22 cells. These data suggested that YVLLPSPK improved learning and memory in scopolamine-induced cognitive-impaired mice through a mechanism associated with PINK1-mediated mitophagy via the NRF2/KEAP1/HO-1 pathway
The effects of power on-off durations of pulsed ultrasound on the destruction of cancer cells.
No full text
Resensies: Hy kom met die skoenlappers. ’n Elegie aan verlore liefde
No full textBook Title: Hy kom met die skoenlappers. ’n Elegie aan verlore liefdeBook Author: Valda JansenKaapstad: Human & Rousseau, 2016. 184 pp. ISBN 978 0 79817 252 3
Moisture content and different rates of urea application affect the nutritive quality of wheat straw
No full textKotieläintieteen päivien järjestäjät: HY/Kotieläintieteen laitos, MTT/Kotieläintuotannon tutkimuslaitos, Maaseutukeskusten Liittovo
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