84 research outputs found
Supplementary_material - Analysis of Hepatitis B Virus Reactivation After Radiotherapy in Patients With Hepatocellular Carcinoma Using the Lyman NTCP Model
No full textSupplementary_material for Analysis of Hepatitis B Virus Reactivation After Radiotherapy in Patients With Hepatocellular Carcinoma Using the Lyman NTCP Model by Zhenjiang Li, Yinping Dong, Min Fan, Yong Yin, Jian Zhu, Baosheng Li and Wei Huang in Technology in Cancer Research & Treatment</p
Formation of ripples in atomically thin MoS2 and local strain engineering of electrostatic properties
No full textRipple is a common deformation in two-dimensional materials due to localized strain, which is expected to greatly influence the physical properties. The effects of the ripple deformation in the MoS2 layer on their physics, however, are rarely addressed experimentally. We here grow atomically thin MoS2 nanostructures by employing a vapor phase deposition method without any catalyst and observed the ripples in MoS2 nanostructures. The MoS2 ripples exhibit quasi-periodical ripple structures in the MoS2 surface. The heights of the ripples vary from several angstroms to tens of nanometers and the wavelength is in the range of several hundred nanometers. The growth mechanism of rippled MoS2 nanostructures is elucidated. We have also simultaneously investigated the electrostatic properties of MoS2 ripples by using Kelvin probe force microscopy, which shows inhomogeneous surface potential and charge distributions for MoS2 ripple nanostructures with different local strains. © 2015 IOP Publishing Ltd
Magnetically coupled resonance wireless charging technology principles and transfer mechanisms
No full textCharacterization of the Roles of Kafirin Genes in Sorghum Grain Quality
No full textSorghum (S. bicolor) is globally recognized for its agricultural importance, primarily used for animal feed and biofuel production. However, problems with low calorific and nutritional contents limit its potential as a food product. One major cause of these limitations is the low content and digestibility of storage proteins in the sorghum grain. Kafirin encoded by 25 genes constitutes a substantial portion (approximately 77-82%) of the protein bodies within the sorghum endosperm. This project aims to systematically understand each kafirin gene's role in the grain quality by characterizing kafirin gene mutants. From our large-scale mutants, we have isolated the homozygous mutants for each kafirin gene. Utilizing single kernel characterization system (SKCS) and nuclear infrared spectroscopy (NIR), we observed alterations in kernel hardness, weight, and size across all kafirin mutants. Our investigation revealed changed protein content and digestibility in the mutants compared to the wild type. Alpha kafirin-9 exhibited the
lowest digestibility, whereas gamma kafirin 23 displayed the highest digestibility compared to BTx623. Scanning electron microscopy analysis of mutant lines, including the wild type, revealed morphological changes in both floury and vitreous endosperm. High-performance liquid chromatography (HPLC) confirmed the absence of gamma kafirin peaks, validating the knockout mutation. This comprehensive study enhances our understanding of kafirin's impact on sorghum grain quality, potentially facilitating significant advancements in food security and nutrition.Embargo status: Restricted until 06/2025. To request the author grant access, click on the PDF link to the left
Abundant grain boundaries activate highly efficient lithium ion transportation in high rate Li<sub>4</sub>Ti<sub>5</sub>O<sub>12</sub> compact microspheres
No full textIt is a huge challenge for high-tap-density electrodes to achieve high volumetric energy density but without compromising the ionic transportation. Herein, we prepared compact Li4Ti5O12 (LTO) microspheres consisting of densely packed primary nanoparticles. The real space distribution of lithium ions inside the compact LTO was revealed by using scanning transmission electron microscopy with electron energy loss spectroscopy (STEM-EELS) to identify the function of grain boundaries for lithium ion transportation during lithiation. The as-prepared LTO microspheres possess a high tap density (1.23 g cm-3) and an ultra-small specific surface area (2.40 m2 g-1). Impressively, the compact LTO microspheres present excellent electrochemical performance. At high rates of 5C, 10C and 20C, the LTO microspheres show a specific capacity of 146.6, 138.2 and 111 mA h g-1, respectively. The capacity retention remains at 97.8% at 5C after 500 cycles. The STEM-EELS results indicate that the lithiation reaction of LTO is firstly initiated at grain boundaries during the high rate lithiation process and then diffuses to the bulk area. The abundant grain boundaries in compact LTO microspheres can form a highly efficient conductive network to preferentially transport the ions, which contributes to high volumetric and gravimetric energy density simultaneously.Accepted Author ManuscriptRST/Fundamental Aspects of Materials and EnergyRST/Storage of Electrochemical Energ
Role of miRNAs in carbon metabolism and stress responses in Arabidopsis thaliana mitochondrial uncoupling protein mutants ucp1/2/3 and activation-tagged transcription factor allele PRODUCTION OF ANTHOCYANIN PIGMENT/PAP1-D/MYB75
No full textPlant sugars, specifically the transported disaccharide primary product of photosynthesis sucrose, control multiple aspects of the plant life cycle including structure, growth, and development. Notably, sucrose functions as a signaling molecule by unknown molecular mechanisms to facilitate various stress adaptations. Accumulation of high sugar concentrations in plants is a hallmark associated with many environmental stimuli, abiotic, and biotic stresses, resulting in accumulation of antioxidant secondary carbon metabolites anthocyanins and flavanoids. From a regulatory perspective, some microRNAs (miRNAs) are potentially components of sucrose signaling pathways because of their established roles in secondary carbon metabolism. However, current understanding of the role of miRNAs in sucrose signaling pathway is very scarce. In this study, I endeavored to uncover the effect of exogenous high sucrose stress on miRNA profiles in Arabidopsis mitochondrial uncoupling protein mutants (ucp) that are defective in reactive oxygen species (ROS) homeostasis and pap1-D, a positive effector transgene mutant of secondary metabolite anthocyanin pathway. My aim is to better understand the UCP protein roles in response to oxidative stress and subject to regulatory control by sugar signaling, and to ascertain the importance of miRNAs impacting primary metabolism and regulation of carbon partitioning to the secondary metabolite pathways antioxidant anthocyanins and flavanols. Qualitative measurements of ROS hydrogen peroxide and superoxide abundance with specific chromogenic stains showed higher endogenous ROS in sucrose-treated samples. My analysis of small RNA deep sequencing datasets from sucrose-treated mutant and wild-type seedlings shows that high exogenous sucrose treatment altered the expression of many miRNAs inferred to be involved in primary metabolism, stress responses, hormone and nutrient signaling pathways, secondary metabolism and vegetative and reproductive development. Moreover, messenger RNA transcriptomic datasets from the same experiments shows a substantial reduction of photosynthesis- related genes and an induction of the genes and regulatory transcription factors involved in flavonoid pathway which was further evidenced by a very high accumulation of anthocyanin in all genotypes, especially pap1-D/MYB75 overexpression which showed some genotype-by-sucrose interaction effects. My sRNA-/mRNA-seq systems approach revealed evidence of a retrograde signaling mechanism from UCP family member proteins in the mitochondrial inner membrane to the genome-wide reprogramming of gene expression for carbon partitioning pathways from primary to secondary antioxidant metabolites, including post-transcriptional control.Embargo status: Restricted until 01/2025. To request the author grant access, click on the PDF link to the left
Influence of droplet coalescence and breakup on the separation process in wave-plate separators
No full textEvaluation of Potential for Salt Cavern Gas Storage and Integration of Brine Extraction: Cavern Utilization, Yangtze River Delta Region
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