187,915 research outputs found
Editorial: venom collection
Venoms are naturally available biological resources with a huge potential to explore numerous pharmacologically valuable compounds to diagnose and treat human diseases. Therefore, researching venoms is not only beneficial to develop better diagnostic and therapeutic approaches for envenomation, but also to explore the clinical potential of a plethora of molecules. This special Collection includes a range of articles that report a variety of research on the development of diagnostic methods for venom detection and toxicity of venoms in various cellular systems. We believe that this Collection extends the knowledge and offers potential avenues to initiate new lines of research in this field
Petrels
Los petreles son aves marinas pelágicas de amplia distribución y particularmente abundantes en los mares fríos y templados. Se caracterizan por tener excelentes capacidades de vuelo y realizar extensos viajes de alimentación. Junto con los albatros y las pardelas forman parte del Orden Procellariiformes, que reúne 37 especies de aves marinas. En el Mar Patagónico se alimentan aproximadamente 23 especies de petreles, pero solo el petrel gigante del sur (Macronectes giganteus) se reproduce en las costas patagónicas. En las Islas Malvinas se reproducen 7 especies, entre ellas el petrel negro (Procellaria aequinoctialis). En las Islas Georgias del Sur se reproduce el petrel gigante del norte (Macronectes halli), visitante frecuente del Mar Patagónico.(Macronectes giganteus) se reproduce en las costas patagónicas. En las Islas Malvinas se reproducen 7 especies, entre ellas el petrel negro (Procellaria aequinoctialis). En las Islas Georgias del Sur se reproduce el petrel gigante del norte (Macronectes halli), visitante frecuente del Mar Patagónico.(Procellaria aequinoctialis). En las Islas Georgias del Sur se reproduce el petrel gigante del norte (Macronectes halli), visitante frecuente del Mar Patagónico.. En las Islas Georgias del Sur se reproduce el petrel gigante del norte (Macronectes halli), visitante frecuente del Mar Patagónico.Fil: Quintana, Flavio Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Nacional Patagónico; Argentina. Wildlife Conservation Society; Estados UnidosFil: Croxall, John. BirdLife International; RusiaFil: González Solís, Jacob. British Antarctic Survey; RusiaFil: Phillips, Richard. British Antarctic Survey; RusiaFil: Trathan, P.. British Antarctic Survey; RusiaFil: Falabella, Valeria. Wildlife Conservation Society; Estados Unido
Caratterizzazione molecolare di un gene del polydnavirus di Cardiochiles nigriceps (CnPDV) espresso in ospiti parassitizzati.
Bioconverter insects: A good example of circular economy, the study case of hermetia illucens
The production cycle based on extraction, transformation, production, consumption and waste has not been sustainable for years. The goal is to have production cycles capable of self-regeneration, and therefore to identify a new way of managing byproducts is needed, one that would turn them into a resource. In the production cycle of the food industry, losses and waste account for about 1,3 billion of tons a year, and thus around 1/3 of world production for human consumption. Insects can represent a valid solution to the reuse and valorization of food industry by-products. In environmental and economic fields, an innovative application is offered by the capacity of some insects to bioconvert waste material into valuable products. Bioconverter insects can valorize organic waste from the agrifood industry through bioconversion. This process allows to obtain numerous products of high biological and economic value: proteins and lipids of animal origin, chitin and residues from the bioconversion process (frass of insect and partially digested organic material, rich in in uric acid and chitin, comparable to soil conditioner for agriculture and therefore usable for crop fertilization). Proteins and lipids deriving from some insect species could be used for feed production, and lipids can be exploited for the production of biodiesel or could find application in cosmetics field. Moreover, insect's chitin and its derivative chitosan can find many possible applications in agricultural, biomedical, pharmaceutical and industrial fields as well as in wastewater treatment. The breeding of insects for animal feed and as an alternative source of energy could represent one of the solutions to be adopted in the future. To date, in Europe the larval biomass obtained from bioconversion process can be marketed for the feeding of game animals, reptiles, fur animals and other insectivorous species (EU Reg. 68/2013, EU Reg. 142/2011); they can also be transformed into processed animal proteins (PAP) and then in flours with high nutritional content, to replace or supplement the protein and lipid quotas present in conventional feeds. The specific conditions of processing, production, storage, transport and use of insect flour for aquaculture (fish farming) has been governed by the European Regulation 2017/893 that allows the use of proteins for fish feed derived only from seven species, including the dipteran Hermetia illlucens. In the present paper, we describe the sustainable use of H. illucens to bioconvert agrifood by-products and produce proteins, lipids, chitin and its derivatives; furthermore, we shall outline their applications in the view of a zero-waste circular economy
Interazioni ospite-parassitoide negli insetti: strategie di colonizzazione dell’ospite e ruolo dei fattori parassitari
Integrador : Falabella S. A.
Tesis (Contador Auditor)Falabella invertirá US 353 millones para el año 2021, completando US 443 millones.
La presente crisis sanitaria ha provocado un aumento sostenido en el aumento de compras a través de plataformas digitales, por lo que los resultados del primer trimestre de 2021, en comparación del mismo período en 2020 tiene los siguientes resultados:
• Aumento del 10,7% en ingresos.
• Aumento en 17,5% en beneficio bruto, con un margen del 36,1%.
• Aumento del EBITDA en 66,5%.
• Aumento del beneficio neto del 713,8%, lo que corresponde a US $137,3 millones.
Grupo Falabella es el primer retail chileno en ingresar al Índice de Sostenibilidad Dow Jones para Mercados Emergentes, estando en la categoría Bronze, que reconoce a las empresas que se encuentran entre el 5 y 10% mejor de su industria según el estudio anual “Sustainability Yearbook 2020” realizado por RobecoSAM, principal evaluador de inversiones sostenibles del mundo.
Falabella es reconocida a nivel mundial y el único retail de Chile en obtener el “Premio al Liderazgo 2021” otorgado este mes por el U.S. Green Building Council (USGBC), organización internacional que promueve y estimula la construcción y el desarrollo sustentable.
Según Bice Inversiones, en su informe de carteras recomendadas del 07 de julio de 2021, las acciones de Falabella se encuentran en una tendencia alcista, con recomendaciones de Compra, ya que la acción se encuentra transando por debajo de su promedio histórico de 20 x P/U.
Falabella ha sido capaz de sacar ventaja del actual cambio en la economía mundial, mejorando rápidamente su plataforma de e-commerce, agilizando su logística, medios de pago a través de su billetera digital, adaptando rápidamente medidas de seguridad sanitaria siempre enfocada en el beneficio de la experiencia de compra de sus clientes
Host regulation by the aphid parasitoid Aphidius ervi: the role of teratocytes
The biochemical profile and metabolism of Acyrthosiphon pisum (Harris) (Homoptera, Aphididae) are markedly altered and redirected in response to parasitization by the endophagous braconid Aphidius ervi Haliday (Hymenoptera, Braconidae). In the present study, the role played in the host regulation process by teratocytes, cells deriving from the dissociation of the embryonic membrane of the parasitoid, is taken into consideration. The protein synthesis activity of these cells of embryonic origin is analysed in vitro and an essential characterization of those proteins de novo synthesized and released in the incubation medium is provided. Teratocytes, obtained by dissecting parasitized host aphids, 3, 4 and 5 days after parasitoid oviposition, were incubated in vitro and, at the end of the incubation period, were separated from the medium for SDS-PAGE analysis of both cellular and secreted proteins. Various cellular proteins were more abundant as the time between parasitization and teratocyte collection increased. Furthermore, two proteins, showing an approximate molecular mass of 15 kD (p15) and 45 kD (p45) respectively, were abundantly secreted in the incubation medium by 5 day-old teratocytes. Incubations in presence of S-35 radiolabelled amino acids indicated that p15 and p45 are both synthesized by A. ervi teratocytes. The amino acid composition of these two proteins was similar to that reported for other insect proteins with a demonstrated nutritional function. The p45 protein was found to be glycosylated. A tentative physiological model describing the host regulation role played by different parasitoid-derived factors is proposed
Regulation of Heliothis virescens prothoracic glands by Cardiochiles nigriceps polydnavirus (CnPDV)
Heliothis virescens (F.) larvae parasitized by the endophagous braconid Cardiochiles nigriceps Viereck fail to attain the pupal stage. This developmental alteration is caused by both an inactivation of prothoracic glands of last-instar larvae and an altered ecdysone metabolism. Decrease in ecdysteroidogenesis in vitro was already evident in glands explanted from larvae tl lat have attained the early cell formation stage (day 4 of fifth instar), 6 h after parasitoid oviposition. Ecdysteroidogenesis nearly ceased by 24 h after parasitoid oviposition. The degree of this biosynthetic depression increased as the time between parasitization and gland dissection increased. A time-course study allowed us to determine if both the degree of phosphorylation of regulatory target proteins. the rate of general protein synthesis and ecdysteroidogenesis decreased in concert over time. The results provide further evidence in support of the hypothesis that these cellular activities in prothoracic gland cells are functionally correlated in steroidogenic responses. Treatment with calyx fluid and venom of C. nigriceps duplicates the parasitism-induced inactivation of host prothoracic glands. A 6-h conditioning in vitro of pupally committed host prothoracic glands with these parasitoid female reproductive secretions resulted in a significant depression of their ecdysteroid production. However, glands lost their sensitivity to calyx fluid and venom treatment when explanted from hosts that had already attained the cell formation stage. This was further supported by the fact that nearly all the host larvae parasitized on day 4 of fifth instar (cell formation stage) pupated, while parasitization on day 3 resulted in only 11% pupation. The coupled trioxsalen/UV irradiation treatment of C. nigriceps calyx fluid and venom eliminated their negative effect on biosynthetic activity in vitro by host prothoracic glands. This result indirectly demonstrates that C. nigriceps polydnavirus is the major regulating factor involved in the host prothoracic gland inactivation. (C) 1998 Wiley-Liss, Inc
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