29 research outputs found
Enzymatic synthesis of oligo- and polysaccharide fatty acid esters
No full textAmphiphilic oligo- and polysaccharides (e.g. polysaccharide alkyl or alkyl-aryl esters) form a new class of polymers with exceptional properties. They function as polymeric surfactants, whilst maintaining most of the properties of the starting polymeric material such as emulsifying, gelling, and film forming properties combined with partial water solubility or permeability. At present carbohydrate fatty acid esters are generally obtained by chemical methods using toxic solvents and organic and inorganic catalysts that leave residual traces in the final products. Enzymatic reactions offer an attractive alternative route for the synthesis of polysaccharide esters. In this review the state of the art of enzymatic synthesis of oligo- and polysaccharides fatty esters has been described
Modelling of the oxygen decomposition process of silage
No full textAnalizowano wpływ wybranych warunków początkowych na zmiany stężenia tlenu i koncentracji drożdży w odkrytej warstwie kiszonki bezpośrednio po otwarciu silosu. W tym celu wykorzystano prosty model matematyczny tlenowego rozkładu kiszonek, który uwzględnia zmiany przestrzenno-czasowe tlenu i temperatury opisane równaniami dyfuzji.The impact of selected initial conditions on changes in oxygen concentration and yeast concentration in open silage layer immediately after opening the silo was analyzed. A simple mathematical model of oxygen decomposition of silage was used for this purpose, taking into account spatial and temporal changes of oxygen and temperature, described by using diffusion equations
Mean reduction in weight loss (kg) based on sibutramine and orlistat.
No full text<p>CI, confidence intervals; IV, inverse variance.</p
Localization errors of the stochastic heat equation
No full textIn this thesis, we study the stochastic heat equation (SHE) on bounded domains and on the whole Euclidean space We confirm the intuition that as the bounded domain increases to the whole space, both solutions become arbitrarily close to one another. Both vanishing Dirichlet and Neumann boundary conditions are considered.
We first study the nonlinear SHE in any space dimension with multiplicative correlated noise and bounded initial data. We prove that the solutions to SHE on an increasing sequence of domains converge exponentially fast to the solution to SHE on Uniform convergence on compact set is obtained for all -moments. The conditions that need to be imposed on the noise are the same as those required to ensure existence of a random field solution. A Gronwall-type iteration argument is used together with uniform bounds on the solutions, which are surprisingly valid for the entire sequence of increasing domains.
We then study SHE in space dimension with additive white noise and bounded initial data. Even though both solutions need to be considered as distributions, their difference is proved to be smooth. If fact, the order of smoothness depends only on the regularity of the boundary of the increasing sequence of domains. We prove that the Fourier transform, in the sense of distributions, of the solution to SHE on do not have any locally mean-square integrable representative. Therefore, convergence is studied in local versions of Sobolev spaces. Again, exponential rate is obtained.
Finally, we study the Anderson model for SHE with correlated noise and initial data given by a measure. We obtain a special expression for the second moment of the difference of the solution on with that on a bounded domain. The contribution of the initial condition is made explicit. For example, exponentially fast convergence on compact sets is obtained for any initial condition with polynomial growth. More interestingly, from a given convergence rate, we can decide whether some initial data is admissible.PRO
DataSheet1_A Systematic Review Comparing Animal and Human Scarring Models.docx
No full textIntroductionA reproducible, standardised model for cutaneous scar tissue to assess therapeutics is crucial to the progress of the field. A systematic review was performed to critically evaluate scarring models in both animal and human research.MethodAll studies in which cutaneous scars are modelling in animals or humans were included. Models that were focused on the wound healing process or those in humans with scars from an existing injury were excluded. Ovid Medline® was searched on 25 February 2019 to perform two near identical searches; one aimed at animals and the other aimed at humans. Two reviewers independently screened the titles and abstracts for study selection. Full texts of potentially suitable studies were then obtained for analysis.ResultsThe animal kingdom search yielded 818 results, of which 71 were included in the review. Animals utilised included rabbits, mice, pigs, dogs and primates. Methods used for creating scar tissue included sharp excision, dermatome injury, thermal injury and injection of fibrotic substances. The search for scar assessment in humans yielded 287 results, of which 9 met the inclusion criteria. In all human studies, sharp incision was used to create scar tissue. Some studies focused on patients before or after elective surgery, including bilateral breast reduction, knee replacement or midline sternotomy.DiscussionThe rabbit ear scar model was the most popular tool for scar research, although pigs produce scar tissue which most closely resembles that of humans. Immunodeficient mouse models allow for in vivo engraftment and study of human scar tissue, however, there are limitations relating to the systemic response to these xenografts. Factors that determine the use of animals include cost of housing requirements, genetic traceability, and ethical concerns. In humans, surgical patients are often studied for scarring responses and outcomes, but reproducibility and patient factors that impact healing can limit interpretation. Human tissue use in vitro may serve as a good basis to rapidly screen and assess treatments prior to clinical use, with the advantage of reduced cost and setup requirements.</p
Fragmento del Credo
No full textIglesia Mayor de Nuestra Señora de la AnunciaciónFondo de Recuperación Next Generation E
