73,063 research outputs found
Needles in M Fabian box
No full textDark blue box with white and gold label reading "M Fabian medical supplies" containing needles 11. </p
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A letter and attached resume from Fabian Garcia to Dr. Hector P. Garcia regarding a letter of recommendation.
No full textA letter and attached resume from Fabian Garcia to Dr. Hector P. Garcia regarding a letter of recommendation
From self assembled monolayers to clickable gold nanoparticles
Get PDFThe aim of the present PhD thesis was the investigation of the behavior of gold nanoparticle stabilizing oligo thioether ligands on gold surfaces and further on to develop a protocol for the directed assembly of mono functionalized gold nanoparticle into defined oligomer structures.
Outline
The present cumulative PhD thesis consists of the following parts:
In the Introduction the research field of gold nanoparticles is presented with to point out their unique electronic and physical properties. The second focus will be on the controlled interlinking and functionalization of gold nanoparticles using click chemistry and their potential applications, which will be submitted as a review article.
Within Concept and Strategy the goals of the research project are introduced and the concepts and outputs of the resulting publications are presented.
The Publications are accumulated with their respective Supporting Information, in the order in which they were prepared:
“Loops versus Stems: Benzylic Sulfide Oligomers Forming Carpet Type Monolayers“ F. Sander, T. Peterle, N. Ballav, F. Wrochem, M. Zharnikov, M. Mayor J. Phys. Chem. C, 2010, 114, 4118 – 4125.
“Add a Third Hook: S-Acetyl Protected Oligophenylene Pyridine Dithiols as Advanced Precursors for Self-Assembled Monolayers“ F. Sander, J. P. Hermes, M. Mayor, H. Hamoudi, M. Zharnikov PCCP, 2013, 15, 2836 – 2846.
“Dumbbells, Trikes and Quads - Click Gold Nanopartricles together“ F. Sander, U. Fluch, J. P. Hermes and M. Mayor Small 2014, 10, 349 – 359.
“Click Chemistry with Gold Nanoparticles – A Tool for Functionalization, Interlinking and Labeling” Fabian Sander and Marcel Mayor, manuscript prepared for submission.
Finally, within Conclusion and Outlook the main results are briefly summarized and further potential research is proposed
Total synthesis of (-)-pyridovericin and synthetic studies towards aetheramide B
Get PDFIn this thesis, two projects involving the total synthesis of natural products are presented.
The first part gives an overview on neurodegenerative diseases and introduces the
neuritogenic pyridopolyene natural product (–)-pyridovericin. The enantioselective total
synthesis of (–)-pyridovericin is presented. The key steps were an enantioselective,
iridium-catalyzed hydrogenation of an enoate and an E-selective Horner-Wadsworth-
Emmons reaction. The complex pyridopolyene structure was then truncated and the
neuritogenic core structure identified. Truncated natural product analogs were
synthesized and successfully implemented in a neuritogenic surface material.
The second part reviews the current state of research on HIV and AIDS. Our efforts
towards the total synthesis of the recently isolated HIV-inhibitory natural product
aetheramide B are reported. Three advanced building blocks were synthesized
enantioselectively in good yields. The key steps involved the enantioselective
hydrogenation of an enamide to form an amino ester, the diastereoselective alkynylation
of a homobenzylic aldehyde and the enantioselective reduction of a bromoenone. The
building blocks were then successfully coupled to form the macrocyclic depsipeptide
core structure. The macrocyclic core of aetheramide B was then synthesized in a
macrolactonization reaction
A 2 h periodic variation in the low-mass X-ray binary Ser X-1
No full textSpectroscopy of the low-mass X-ray binary Ser X-1 using the Gran Telescopio Canarias have revealed a ?2 h periodic variability that is present in the three strongest emission lines. We tentatively interpret this variability as due to orbital motion, making it the first indication of the orbital period of Ser X-1. Together with the fact that the emission lines are remarkably narrow, but still resolved, we show that a main-sequence K dwarf together with a canonical 1.4 M? neutron star gives a good description of the system. In this scenario, the most likely place for the emission lines to arise is the accretion disc, instead of a localized region in the binary (such as the irradiated surface or the stream-impact point), and their narrowness is due instead to the low inclination (?10°) of Ser X-1
Stable voters in an unstable party environment : continuity and change in Italian electoral behaviour
Get PDFM.24981-1999 Paolo Segatti, Paolo Bellucci and Marco Maraffi. 30 cm. A previous version of this paper was presented at a symposium on Political Parties : Changing Roles in Contemporary Democracies, held at the Center for Advanced Study in the Social Sciences of the Juan March Institute, Madrid, December 15-17, 1994. -- P.1. Includes bibliographical references (p. 56-59
Jahrbuch für direkte Demokratie 2020
Get PDFBand 10 des Jahrbuchs für direkte Demokratie umfasst vier Abhandlungen. Diese befassen sich mit der direkten Demokratie aus kulturphilosophischer Sicht, mit der Beteiligung bei umweltrelevanten Vorhaben in Deutschland, mit den Entwicklungen der Europäischen Bürgerinitiative und mit der Transparenz in der Politikfinanzierung in der Schweiz. In zwei weiteren Beiträgen wird über die jüngsten Entwicklungen in der Schweiz und in Deutschland berichtet. Die Übersicht zur Rechtsprechung umfasst zentrale Entscheidungen zur direkten Demokratie. Zwei Dokumentationen, ein Verzeichnis neuer Literatur sowie eine Rezension runden das Jahrbuch ab. Mit Beiträgen von Prof. Dr. Odile Ammann; Prof. Dr. Nadja Braun Binder, MBA; Prof. Dr. Dr. h.c. Lars P. Feld; Prof. Dr. Peter M. Huber; Prof. Dr. Matthias Knauff; Eliane Kunz; Liliane Obrecht; Prof. Dr. Arne Pautsch; Prof. Dr. Klaus Poier; Dipl.-pol. Frank Rehmet; Prof. Dr. Andreas Urs Sommer; Prof. Dr. Axel Tschentscher; Prof. Dr. Daniela Winkler und Prof. Dr. Fabian Wittreck
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