1,721,178 research outputs found
Nurses, shift work, and diabetes: should late chronotype be considered as a risk factor?
Shan and colleagues show that duration of rotating night shift work and unhealthy lifestyle are independently and jointly associated with a higher risk of type 2 diabetes in nurses.1 Among the possible determinants of an unhealthy lifestyle, however, they don’t mention disruption of circadian rhythms and chronotype (individual circadian preference)
Is Takotsubo Syndrome Still a Benign Disease? Complications (and Gender) Make the Difference
No abstract availabl
Off-Hours and In-Hospital Mortality: Lower Resources or Higher Severity?
Discussion lette
Heat Stress and Cardiovascular Mortality in Immigrant Workers: Can We Do Something More?
No abstract availabl
Letter by Manfredini et al Regarding Article, "Ambulance Density and Outcomes After Out-of-Hospital Cardiac Arrest: Insights From the Paris Sudden Death Expertise Center Registry"
No abstract availabl
Venous Doppler flow patterns, venous congestion, heart disease and renal dysfunction: A complex liaison
The World Journal of Cardiology published an article written by Kuwahara et al that we take the pleasure to comment on. We focused our attention on venous congestion. In intensive care settings, it is now widely accepted that venous congestion is an important clinical feature worthy of investigation. Evaluating venous Doppler profile abnormalities at multiple sites could suggest adequate treatment and monitor its efficacy. Renal dysfunction could trigger or worsen fluid overload in heart disease, and cardio-renal syndrome is a well-characterized spectrum of disorders describing the complex interactions between heart and kidney diseases. Fluid overload and venous congestion, including renal venous hypertension, are major determinants of acute and chronic renal dysfunction arising in heart disease. Organ congestion from venous hypertension could be involved in the development of organ injury in several clinical situations, such as critical diseases, congestive heart failure, and chronic kidney disease. Ultrasonography and abnormal Doppler flow patterns diagnose clinically significant systemic venous congestion. Cardiologists and nephrologists might use this valuable, non-invasive, bedside diagnostic tool to establish fluid status and guide clinical choices
Acute cholestasis as uncommon onset of Kawasaki disease: a case report
Background: Kawasaki disease (KD) or mucocutaneous lymph node syndrome is a vasculitis that mostly occurs in young children. Adult-onset KD (AKD) is rare and often misdiagnosed. Here we report a rare case of KD with cholestasis as principal symptom.
Case presentation: A 43-year-old caucasian man was admitted to our hospital for high fever, lack of appetite related to nausea and vomiting, headache and significant malaise. Physical examination highlighted fever, increasing jaundice, bilateral laterocervical lymph nodes, erythema of the palms, and strikingly red lips and conjunctiva. The clinical course was complicated by arterial hypotension, tachycardia, decreasing haemoglobin, increasing acute phase reactants tests, and multiorgan failure. Due to cardiovascular instability the patient was admitted to the local Intensive Care Unit. Chest X-ray, abdominal ultrasound, chest and abdominal CT and Colangio Magnetic Resonance were normal. Jaundice was investigated and infections, autoimmune diseases or drugs adverse reactions, were excluded. Also coronary artery computed tomography was carried out excluding coronary artery aneurysms. Broad-spectrum antibiotics were not effective. After exclusion other possible conditions, diagnosis of KD was set. He was treated with high doses of corticosteroids and acetylsalicylic acid and clinical conditions as well as laboratory exams improved.
Conclusions: This report dealing with an adult onset of atypical KD may be of benefit to physicians of various specialties, including primary care doctors, hospital internists, intensivists and gastroenterologists due to its peculiarities. It demonstrates that a case of prolonged fever unresponsive to antibiotics and related to cholestatic jaundice, oedema or erythema of the extremity associated with desquamation of feet and hands, and red eyes, may suggest atypical form of KD
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