1,720,997 research outputs found
Disease eradication in hairy cell leukemia patients treated with 2-chlorodeoxyadenosine.
Interleukin-8 induces the accumulation of B-cell chronic lymphocytic leukemia cells by prolonging survival in an autocrine fashion.
Molecular evaluation of clonal remission in hairy cell leukemia patients treated with 2-chlorodeoxyadenosine.
Microsatellite instability is associated with the histological features of the tumor in nonfamilal colorectal cancer.
Immunoglobulin light chain restriction and clonal rearrangement in nodular paragranuloma.
Phenotypic and genotypic switch in philadelphia positive, bcr positive blast crisis of chronic myeloid leukaemia.
Acute lymphoblastic leukemia with the 4;11 translocation exhibiting early T-cell features.
We describe a case of ALL with the t(4;11) (q21;q23) translocation in which both surface markers and molecular analyses suggest an unusual early T cell involvement. While the morphologic and cytochemical studies showed an undifferentiated pattern, immunophenotypic data were suggestive of a very immature cell population which stained only for TdT and CD7. Moreover, in contrast to previous reports but in agreement with the immunologic findings, the IgH gene region retained a germline configuration. T cell receptor beta and gamma chain gene loci also showed a germline pattern, in accordance with the expansion of immature CD7+, TdT+ T cells
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