146 research outputs found

    Hollow core waveguides for optical chemical sensing

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    Hollow core waveguides employing anti-resonance principle have the capability to confine the optical field in a low index medium. This characteristic can be effectively employed to build very sensitive optical sensors for biochemical and environmental applications. In this paper, a micrometer guiding structure in silicon technology is investigated, providing modal analysis and sensitivity analysis. All the results are obtained by Finite Element Method numerical simulations

    Focal Epilepsy Associated with Glioneuronal Tumors

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    Glioneuronal tumors are an increasingly recognized cause of partial seizures that occur primarily in children and young adults. Focal epilepsy associated with glioneuronal tumors is often resistant to pharmacological treatment. The cellular mechanisms underlying the epileptogenicity of glioneuronal tumors remain largely unknown. The involved mechanisms are certain to be multifactorial and depend on specific tumor histology, integrity of the blood-brain barrier, characteristics of the peritumoral environment, circuit abnormalities, or cellular and molecular defects. Glioneuronal tumors presenting with epilepsy were observed to have relatively benign biological behavior. The completeness of the tumor resection is of paramount importance in avoiding tumor progression and malignant transformation, which are rare in cases of epileptogenic glioneuronal tumors. An evolving understanding of the various mechanisms of tumor-related epileptogenicity may also lead to a more defined surgical objective and effective therapeutic strategies, including antiepileptogenic treatments, to prevent epilepsy in at-risk patients.</jats:p

    A Virtual Hospital for Medical English: Multimodal sequence-based text studies

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    This volume brings together three research strands in the field of Medical English. Over the last 20 years in Italy, courses in English in degree courses in the Faculty of Medicine have continued to grow as have the levels of competence achieved by students. The result has been a dearth of text-based studies that are suitable for the training of students engaged with various aspects of biomedical science. This volume brings together the author’s reflections on aspects that have tended to be neglected in the medical context such as translation and improvements to the organization syntactic structures in biomedical English. The study also embraces analysis of new digital texts and genres that are modifying the medical education landscape with profound effects. The unifying framework is Virtual Hospital, a hypertext template being developed by the author. One part of this is the film medical education training film ForWard which has already been produced by the author in collaboration with others. The volume describes the medical and discourse objectives achievable by integrating ForWard and other texts belonging to various multimodal genres in the Virtual Hospital template

    GEOLOGICAL MAP OF THE GORGOGLIONE BASIN (EASTERN SECTOR)

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    In this paper we report new stratigraphic data related to a new geological map of the Miocene Gorgoglione Basin of southern Italy, traditionally considered as a piggy-back or wedge-top basin filled by a turbidite-like succession. Well exposed outcrops in the study area (eastern sector of the basin) show four unconformities in the Castelmezzano-Pietrapertosa area. Two of these unconformities pass to paraconformities southeastward, in the Cirigliano-Gorgoglione area. Based on new stratigraphic data the “succession of the Gorgoglione Flysch” can be divided into different informal units: Val Miletta formation and Gorgoglione supersynthem. The latter can be subdivided into the Cirigliano and Castelmezzano synthems. The previously established Cirigliano synthem is here divided into three subsynthems. The lowermost sediments of the Gorgoglione Flysch on the eastern sectors correspond to a complex unit (Val Miletta formation) including Numidian-like quartzarenites, Gorgoglionelike sandstones, and, at the top of the formation, an olistostrome of varicoloured clays, belonging to the Argille Variegate Group. The stratigraphic analyses and the biostratigraphic results based on calcareous plankton assemblage, improve the reconstruction of the geometries of the sedimentary bodies and the time-space facies evolution of the synthems. Sedimentologic and petrographic characters of the upper part of the Castelmezzano synthem show a clear fining and thinning upward trend. Medium- and fine-grained arenites, varying in composition from quartz sandstones to siltstones and shales, are locally marked by abundant planktonic foraminifera and are interpreted as contourites. Moreover, the relationships between tectonics and sedimentation are analyzed. The data are used to propose a scheme of the Burdigalian to Tortonian tectono-stratigrafiphic evolution of the eastern sector of the basin

    Design of Bragg Grating Sensors Based on Sub-Micrometer Optical Rib Waveguides in SOI

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    A submicrometer integrated optical sensor based on Bragg gratings in silicon-on-insulator technology is theoretically proposed in this paper. The grating analysis is performed using a mixed numerical approach based on the finite-element method and coupled mode theory. The possibility to use third-order instead of first-order grating is discussed and performances compared, thus overcoming fabrication problems associated to submicrometer scale features. A detection limit of approximately 10 4 refractive index unit has been calculated for a 173- m-long grating. Strategies to further improve this value have been discussed too. Finally, fabrication tolerances influence on optimized gratings has been investigated
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