263,173 research outputs found

    Myathropa florea

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    <p> <i>Myathropa florea</i> (Linnaeus, 1758).</p> <p>Regions: UC, GO, SS, CA, CK, CL, DR, MU, CS, LC, SA.</p> <p> Reference: Scopoli (1763) (as <i>Conops floreus</i>), Strobl (1893a, 1893b, 1910), Glumac (1956) (as <i>Myathropa florea</i> var. <i>flavofemorata</i>, <i>Myathropa florea</i> var. <i>florea</i> and <i>Myathropa florea</i> var. <i>nigrotarsata</i>), Coe (1960), Lambeck (1968), Glumac (1972), de Groot (2004), de Groot & Govedič (2008), Van Steenis <i>et al</i>. (2013).</p>Published as part of <i>Kočić, Anja, Vujić, Ante, Tot, Tamara, Milosavljević, Marina Janković & Groot, Maarten De, 2023, An updated checklist of the hoverflies (Diptera: Syrphidae) of Slovenia, pp. 189-227 in Zootaxa 5297 (2)</i> on page 204, DOI: 10.11646/zootaxa.5297.2.2, <a href="http://zenodo.org/record/7993180">http://zenodo.org/record/7993180</a&gt

    Apis florea Fabricius 1787

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    Apis florea FABRICIUS,1787 Apis florea FABRICIUS, 1787: STEINER 2017: (biol., Camp Lemonnier). D i s t r i b u t i o n:CampLemonnier. Apis florea, which is widely distributed in the Oriental region, is also known from the Afrotropical (Djibouti, Ethiopia, Sudan) and Palaearctic regions.Published as part of Madl, Michael, 2018, A preliminary catalogue of the Hymenoptera (Insecta) of the Republic of Djibouti, pp. 907-967 in Linzer biologische Beiträge 50 (2) on page 933, DOI: 10.5281/zenodo.377645

    Florea Shelley 1996

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    Genus <i>Florea</i> Shelley, 1996 <p> <i>Florea</i> Shelley, 1996:46; 2002a:106. Hoffman, 1999:205. Shelley et al. 2000:58. Stoev et al, 2008:38.</p> <p> <b>Type-species</b>. <i>F. sinuata</i> Shelley, 1996, by original designation.</p> <p> <b>Diagnosis</b> (adapted from that in Shelley [1996]). Transition to full number of dorsal carinae on segment 8. Telopodal stem long, slender, and strongly sinuate, without true prefemoral process; division point apical and with basal lobe, with three apical or slightly subapical projections directed generally horizontally, subperpendicular to stem. Tibiotarsus directed subcaudad, moderately long, subequal in length to solenomere branch; latter directed subanteriad, not redivided and thus constituting the solenomere itself, process ‘A’ absent; process ‘B’, apparently representing relocated prefemoral process, subapical, shorter than other projections, directed generally horizontally but curving ventrad near midlength.</p> <p> <b>Species</b>. One.</p> <p> <b>Distribution</b>. Known definitely only from the Trabuco Ranger District, Cleveland Nat. For., Orange Co., California; it probably also occurs near the San Juan Guard Station in this forest (Shelley 1996, 2002a; Hoffman 1999; Shelley et al. 2000; Stoev et al. 2008).</p>Published as part of <i>Shelley, Rowland M. & Richart, Casey H., 2014, Tynommatidae, n. stat., a family of western North American millipeds: Hypotheses on origins and affinities; tribal elevations; rediagnoses of Diactis Loomis, 1937, and Florea and Caliactis, both Shelley, 1996; and description of D. hedini, n. sp. (Callipodida: Schizopetalidea), pp. 1-19 in Insecta Mundi 2014 (340)</i> on page 7, DOI: <a href="http://zenodo.org/record/5178595">10.5281/zenodo.5178595</a&gt

    Summary of gene family classification among four species, <i>S. endius</i>, <i>N. vitripennis</i>, <i>A. florea</i> and <i>D. melanogaster</i>.

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    <p>Summary of gene family classification among four species, <i>S. endius</i>, <i>N. vitripennis</i>, <i>A. florea</i> and <i>D. melanogaster</i>.</p

    Lu AA21004, a multimodal psychotropic agent, in the prevention of relapse in adult patients with generalized anxiety disorder

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    The purpose of this study was to investigate the long-term maintenance of the efficacy of Lu AA21004 5 or 10 mg/day in the prevention of relapse in patients with generalized anxiety disorder (GAD). Patients (n = 687) with a primary diagnosis of GAD (DSM-IV criteria) and a baseline Hamilton Anxiety (HAM-A) total score of at least 20 underwent a 20-week, open-label Lu AA21004 treatment. In all, 459 patients responded and were randomized to 24-56 weeks of a double-blind treatment with Lu AA21004 (n = 229) or placebo (n = 230). The predefined primary efficacy endpoint was time to relapse (HAM-A total score ? 15) using a Cox model; the key secondary efficacy endpoint under multiplicity control was time to relapse for patients responding to treatment for at least 12 weeks. The primary analysis showed a statistically significant effect of Lu AA21004 relative to the placebo on the time to relapse of GAD, with a hazard ratio of 2.71 (P &lt; 0.001). There was a statistically significant effect of Lu AA21004 in the stable responders (hazard ratio = 3.06, P &lt; 0.001). Lu AA21004 was well tolerated, with withdrawal rates due to adverse events of 9% (open-label) and 3% (placebo) and 4% (Lu AA21004) in the double-blind period. In this study, Lu AA21004 5 or 10 mg/day was efficacious in preventing relapse and was well tolerated in the maintenance treatment of GAD.<br/

    Effect of a variable hepatic insulin clearance on the postprandial insulin profile : insights from a model simulation study

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    The liver plays a pivotal role in determining postprandial insulin levels because it is responsible for the extraction of a large (approximately 50%) fraction of the newly secreted insulin by the pancreas. Evidence exists that hepatic insulin extraction is not constant during a meal, but is inhibited because of saturable receptor-mediated mechanisms and/or increase in hepatic blood flow. The aim of the present study was to exploit the ability of mathematical model simulation to shed light on the role of a variable hepatic insulin extraction during a meal. Mathematical models of insulin secretion and kinetics were coupled to provide predictions for the concentration of insulin in plasma following a meal under the assumptions of either a constant or a time-varying hepatic insulin clearance. Our results indicate that a 20% inhibition in hepatic clearance is able to remarkably enhance the plasma insulin level following a meal. These results emphasise the need for simple and accurate methods to measure the time course of hepatic insulin extraction under nonsteady-state conditions

    Vortioxetine (Lu AA21004) in the long-term open-label treatment of major depressive disorder

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    OBJECTIVE: The primary objective of this study was to evaluate the safety and tolerability of the investigational drug vortioxetine (Lu AA21004) in the long-term treatment of patients with major depressive disorder.METHODS: Patients entered this 52-week, open-label extension study after completing an 8-week lead-in study. Safety and tolerability were evaluated at regular intervals on the basis of spontaneously reported adverse events (AEs), clinical safety laboratory tests, vital signs, ECG and physical examination. Effectiveness of treatment was assessed using the Montgomery-Åsberg Depression Rating Scale (MADRS) total score.RESULTS: A total of 535 patients were treated and 61.3% (n?=?328) completed the study, resulting in 393 patient years of exposure to vortioxetine. AEs reported by ?10% of patients were nausea, headache, and nasopharyngitis. Taken together, six patients had eight AEs related to sexual dysfunction. There were no clinically significant safety findings with respect to mean changes of vital signs, weight, ECG parameters, or clinical laboratory values. Patients entered the extension study with a mean MADRS total score of 13.5?±?8.7. The mean MADRS total score decreased (improved) by approximately 8 points to 5.5?±?6.0 at Week 52 (OC). By the end of the study, the proportion of responders had increased from 63% to 94% (OC), as had the proportion in remission (MADRS ?10), increasing from 42% to 83% (OC). Patients in remission (n?=?226) at the start of this study had a relapse rate (MADRS ?22) of 9.7%.CONCLUSIONS: As with all open-label studies, the conclusions that can be drawn are limited by the lack of a placebo control, making it difficult to assess causality of any changes in outcome measures. However, on the basis of these findings, vortioxetine (2.5, 5, 10?mg/day) demonstrated a favourable safety and tolerability profile and maintained effectiveness over 12 months of treatment.<br/

    Aşezarea dacică de la Copăcel, jud. Braşov / La station dace de Copăcel, dép. de Braşov

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    Costea Florea. Aşezarea dacică de la Copăcel, jud. Braşov / La station dace de Copăcel, dép. de Braşov. In: Materiale şi cercetări arheologice, N°17 1992. A XVII-A sesiune anuală de rapoarte, Ploiești 1983 (Partea I) pp. 141-143

    Andrena (Poliandrena) florea Fabricius 1793

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    &lt;i&gt;Andrena&lt;/i&gt; (&lt;i&gt;Poliandrena&lt;/i&gt;) &lt;i&gt;florea&lt;/i&gt; Fabricius, 1793 &lt;p&gt;Global distribution: West-Palearctic&lt;/p&gt; &lt;p&gt;Regional distribution: Casablanca-Settat; Guelmim-Oued Noun; Marrakech-Safi; Rabat-Sal&eacute;-K&eacute;nitra; Souss-Massa&lt;/p&gt; &lt;p&gt; References: Warncke (1974); Gusenleitner &amp; Schwarz (2002); Rasmont &lt;i&gt;et al.&lt;/i&gt; (2013)&lt;/p&gt;Published as part of &lt;i&gt;Lhomme, Patrick, 2020, The wild bees (Hymenoptera: Apoidea) of Morocco, pp. 1-159 in Zootaxa 4892 (1)&lt;/i&gt; on page 17, DOI: 10.11646/zootaxa.4892.1.1, &lt;a href="http://zenodo.org/record/4309281"&gt;http://zenodo.org/record/4309281&lt;/a&gt

    OPPORTUNITY COST OF EDUCATIONAL HUMAN CAPITAL INVESTMENT. APPLICATION FOR THE POSITION OF BENEFICIARY-INVESTOR

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    The present paper focuses on providing a model of applying the opportunitycost concept on investments in human educational capital. In the first part we haveshown that the real costs of educational capital investment does not involve direct andindirect educational costs only but also the opportunity costs, i.e. the earnings that arelost by choosing to invest in education (and not in something else). From our researchthere results the fact that the share of the opportunity cost within the total of theinvestment in educational capital is 60% that is a great share in rapport with other typesof investments. Further on, we have shown that the recovery of the investment isdetermined by two main factors: money and time. The first factor is the growth of revenuethat the skills acquired through higher education bring into relation with the situation"without education" and the second is the duration measured in years, in order that thequestion of revenue growth, investment are fully recovered and bring additional revenue(similar profit). The main conclusion of the present paper is that investment in educationhas a significant positive effect on the dynamics of the relationship between age andearnings, which weakens or even undoes the effect of the high level of opportunity cost ofthis type of investment. The argument for investment in human capital and education plus"non-market income" or "non-monetary effects" of education relates mainly to the rolethat education has on the quality of life. As a long term investment, education brings apermanent increased certainty of a better situation and it increases social developmentand social promotion.opportunity cost, educational human capital, investment in education
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